BMBS051 Biostatistics - basic course

Faculty of Medicine
Autumn 2013
Extent and Intensity
3/0/0. 2 credit(s) (plus 1 credit for an exam). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Ladislav Dušek, Ph.D. (lecturer)
RNDr. Jiří Jarkovský, Ph.D. (lecturer)
RNDr. Jan Mužík, Ph.D. (assistant)
RNDr. Eva Gelnarová (assistant)
Supervisor
doc. RNDr. Ladislav Dušek, Ph.D.
Institute for Biostatistics and Analyses of the Faculty of Medicine - Other Departments for Educational and Scientific Research Activities - Faculty of Medicine
Contact Person: doc. RNDr. Ladislav Dušek, Ph.D.
Dodavatelské pracoviště: Institute for Biostatistics and Analyses of the Faculty of Medicine - Other Departments for Educational and Scientific Research Activities - Faculty of Medicine
Prerequisites
VLLM0522p Medical Microbiology II - lect && VLIM051p immunology-lecture && ( VSBC041p Biochemistry II -l || VSBC0422p Biochemistry II -l ) && VSIP0622c Clin.exam.in int.med.-pract.
None - basic course.
Course Enrollment Limitations
The course is offered to students of any study field.
Course objectives
Introduction to statistics, testing of hypotheses.
Tables of distribution functions.
Introduction to sampling design.
Distribution of continuous and bivariate variables.
Application of binomial and Poisson distribution in biology.
One sample testing.
Two sample testing.
Application of goodness-of-fit test in biology.
Measures of similarity in ecology.
Analysis of variance (ANOVA).
Simple linear regression. Linear regression.
Experimental design. Non - parametric ANOVA.
Syllabus
  • Introduction to statistics, testing of hypotheses.
  • Tables of distribution functions. Sampling from biological populations, data processing.
  • Introduction to sampling design. Continuous, ordinal and nominal data in biology.
  • Distribution of continuous and bivariate variables - testing of hypotheses, graphical methods.
  • Application of binomial and Poisson distribution in biology.
  • One sample testing: sample mean, median, standard deviation, variance, binomial p and Poisson constant.
  • Two sample testing. Experimental design - randomized and blocked. Parametric and non - parametric methods.
  • Application of goodness-of-fit test in biology, analysis of R x C contingency tables, discrimination of categorical data.
  • Measures of similarity in ecology (covariance, correlation coefficients, similarity coefficients).
  • Analysis of variance (ANOVA): one-way and two-way model.
  • Simple linear regression. Linear regression. Introduction to multivariate linear regression.
  • Experimental design: one-way and two-way models; factorial design, randomized blocks. Laboratory and field trials. Nested design of ANOVA in genetics and ecology. Non - parametric ANOVA.
Literature
  • Zar, J.H. (1994) Biostatistical methods. Prentice Hall, London. 2nd ed.
  • G. W. Snedecor, W. G. Cochran (1971). Statistical methods. Iowa State University Press.
  • Statistika pro biologické a lékařské vědy. Edited by Tomáš Havránek. 1. vyd. Praha: Academia, 1993. 478 s. ISBN 80-200-0080-1. info
  • J. Benedík, L. Duąek (1993) Sbírka příkladů z biostatistiky. Nakladatelství KONVOJ, Brno.
Teaching methods
Theoretical lectures supplemented by commented examples; students are encouraged to ask quaetions about discussed topics.
Assessment methods
Course is finished by written exam aimed on principles, prerequisties and correct selection of methods for solution of practical examples.
Further comments (probably available only v češtině)
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
Teacher's information
http://www.cba.muni.cz/vyuka/
Navazující předměty vyučované na PřF MU: Bi5041 Biostatistický seminář I; Bi5042 Biostatistický seminář II; Bi5043 Biostatistický seminář III; Bi7490 Základy stochastického modelování; Bi8600 Vícerozměrné statistické metody
The course is also listed under the following terms Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012.
  • Enrollment Statistics (Autumn 2013, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2013/BMBS051

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