VSAT081 Fundamentals of Antimicrobial Therapy

Faculty of Medicine
Spring 2013
Extent and Intensity
2/0. 3 credit(s). Type of Completion: k (colloquium).
Teacher(s)
MUDr. Lenka Černohorská, Ph.D. (lecturer)
MUDr. Renata Tejkalová (lecturer)
Ing. Veronika Holá, Ph.D. (seminar tutor)
MUDr. Ondřej Zahradníček (assistant)
Supervisor
prof. MUDr. Miroslav Votava, CSc.
Department of Microbiology - Institutions shared with St. Anne's Faculty Hospital - Faculty of Medicine
Contact Person: MUDr. Renata Tejkalová
Dodavatelské pracoviště: Department of Microbiology - Institutions shared with St. Anne's Faculty Hospital - Faculty of Medicine
Timetable
Mon 25. 2. to Fri 31. 5. Tue 16:50–18:30 N02011
Prerequisites
( VLLM0421c Med.Microbiol. && VLLM0522c Medical Microbiology II-pract. ) || ( STLM0421c Medical Microbiology - practice && STLM0522c Medical Microbiology II-prac. )
Subject is recommended for 4th and 5th year students, mostly after having exam from farmacology.
Course Enrollment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
Fields of study the course is directly associated with
Course objectives
The subject gives gives larger knowledge of antibiotics and their use in medical microbiology. Main objectives can be summarized as follows:
* to review a survey of medically important antimicrobial drugs, to get more practical information concerning individual groups of antibiotics (mostly from the point of view of a general practicioner)
* to have survey of factors of resistance of bacteria, and to know, what are the multiresistant strains of bacteria and what is their importance (MRSA, producents of ESBL, VRE etc.) * to get some information concerning basic guidelines for treatment of infections of respiratory ways, gastrointestinal tract, urinary system, genital system, bloodstream, tissues; hospital infections
* to understand basically treatment of immunocompromised persons, pregnant and lactating females, newborns and small babies
Syllabus
  • I. Theoretical basis of action of antimicrobial drugs
  • 1. Classification of antimicrobial agents, comparison with decontamination methods. Term "antibiotic", primarilly bactericidal and bacteriostatical antibiotics.
  • 2. Individual groups of antibiotics according to chemical simillarity and effect mechanism - I Betalaktam antibiotics, penicillins, cephalosporins, monobactams, carbapenems, polypeptides, quinolones
  • 3. Individual groups of antibiotics according to chemical simillarity and effect mechanism - II Aminoglykosides, amphenicols, tetracyclins, macrolides (including azalides and ketolides), lincosamids, sulphonamids, glycopeptids, ansamycins, other atbs
  • 4. Survey of main mechanisms or resistance. Resistance to beta-lactam antibiotics: beta-lactamases, PBP alteration, decrease of permeability. Betalaktamases globally. In vitro testing of susceptibility and resistance.
  • 5. Epidemiologically important factors of resistance. ESBL. MRSA and MRSCN. Resistance to glycopeptides, VRE, VISA and VRSA. Note about other important resistance factors (to aminoglycosides, to macrolides, mostly MLS type in streptococci and staphylococci). Importance of nosocomial strains with factors of increased rezistence, Their surveillance and measures when they occur. Detection of individual resistance factors
  • II. Treatment of infections of individual organ systems in practice
  • 6. Basics of antibiotic treatment of bloodstream infections, proper blood culture sampling, interpretation of finding in relation to therapy
  • 7. Basics of treatment of locomotor system, pyogene and anaerobic infections. Penetration of individual antibiotic groups to the tissues. Basics of antibiotic treatment of neural system and eye
  • 8. Antibiotic treatment in gastrointestinal infections, including stomatological problems. Basics of antibiotic treatmnt of respiratory infections and otitis.
  • 9. Basics of antibiotic therapy of urinary, genital and skin infections. 10. Basics of use of antivirotics, antimycotics and antiparasital drugs in various infections
  • III. Treatment of special cases. Basics of proper practice, treatment economics
  • 11. Treatment of neutropenic patients.
  • 12. Basic rules for treatment in liver and kidney problems, in pregnancy, lactation and in children
  • 13. Basics of proper antibiotic practice, antibiotic centers, prescription limits, economy of antimicrobial treatment.
  • 14. Theme reserved
Literature
  • Powerpointové prezentace, dostupné ve studijních materiálech. - Powerpoint slideshows, available in Study materials
Assessment methods
Time schedule: Subject has the form of two-lesson seminars.
To get the coloquium, students have to be succesful at the coloquial test, and also to participate on the lessons (max. 3 absences, partially may be substituted by a referate, more info on the first lesson).
Further comments (probably available only v češtině)
Study Materials
The course is taught only once.
Information on the extent and intensity of the course: 14 x 2 hodiny.
Listed among pre-requisites of other courses
Teacher's information
Na jaře 2010 je předmět vyučován v úterý 16.50 až 18.30 v posluchárně I. patologického ústavu, budova H, FN u sv. Anny. E-mailový a telefonický kontakt - E-mail and phone contact:

MUDr. Renata Tejkalová: renata.tejkalova@fnusa.cz, TEL 543 183 096 (popřípadě 543 183 109, 543 183 097)

Doc. MUDr. Filip Růžička, PhD: fruzic@fnusa.cz, TEL 543 183 090 (přednosta ústavu/head)

prof. MUDr. Miroslav Votava, CSc.: miroslav.votava@fnusa.cz, TEL 543 183 117

as. MUDr. Ondřej Zahradníček: zahradnicek@fnusa.cz, TEL 543 183 113

odb. as. MUDr. Lenka Černohorská, PhD.: lenka.cernohorska@fnusa.cz, TEL 543 183 097

odb. as. Mgr. Monika Dvořáková Heroldová, PhD: monika.heroldova@fnusa.cz

as. Mgr. Barbora Žaloudiková: barzal@cktch.cz

as. Mgr. Martina Mahelová: 150878@mail.muni.cz

Předmět převážně vyučuje dr. Tejkalová, vedoucí antibiotického střediska Mikrobiologického ústavu LF MU a FN u sv. Anny v Brně. (Dr. Tejkalová je převážně zaměstnankyní fakultní nemocnice, proto ji nenajdete v seznamu kmenových učitelů ústavu.)

The course is also listed under the following terms Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2014.
  • Enrollment Statistics (recent)
  • Permalink: https://is.muni.cz/course/med/spring2013/VSAT081

Other references: 

Go to top | Current date and time: 24. 5. 2013 00:30, Week 21 (odd)

Contact: istech(zavináč/atsign)fi(tečka/dot)muni(tečka/dot)cz, Office for Studies, access rights administrators, is-technicians, e-technicians, IT support | learn more about Information System