PřF:C8858 Biocatalysis - Course Information
C8858 Biocatalysis
Faculty of ScienceAutumn 2008
- Extent and Intensity
- 2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- Teacher(s)
- prof. RNDr. Zbyněk Prokop, Ph.D. (lecturer)
- Guaranteed by
- prof. RNDr. Zbyněk Prokop, Ph.D.
National Centre for Biomolecular Research – Faculty of Science - Prerequisites (in Czech)
- - basic course of biochemistry and organic chemistry recommended - course of microbiology and molecular biology helpful
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- there are 18 fields of study the course is directly associated with, display
- Course objectives
- Biocatalysis is the utilization of natural catalysts, called enzymes, to perform chemical transformations on organic compounds. Biocatalysis is multidisciplinary integration of emerging technologies from life sciences like bioinformatics, protein engineering (rational design and/or in vitro enzyme evolution), medium engineering and immobilization of the biocatalyst for optimum performance and recycling. Biocatalytical application covers the production of fine and bulk chemicals, pharmaceuticals and agrochemicals, environmental application, application in food industry as well as utilisation for analytical processes and diagnostics. The biocatalysis fulfills the concept of sustainable development with minimizing environmental impact (lowering waste production, energy and material consumption). The Biocatalysis course gives basic information about enzyme structure and function, clasification, production and purification of enzymes, enzyme engineering, development of biocatalytical industrial process and outlines the technical and economical potential of enzyme application, giving many examles of industrial processes using enzymes as biocatalyst. At the end of this course, students should be able to: be familiar with the interdisciplinary approach required to utilize the catalytic potential of natural biomolecules, enzymes, or whole cells for the production of useful compounds understand the concept of sustainability and modern, environmentaly acceptable trends in industrial chemistry understand the basic principles of enzymatic reactions and when these catalysts are prefered have overview of reaction types, conditions and method for monitoring of biocatalytic proceses have knowledge how to obtain and optimise/improve enzyme catalysts select optimal biocatalyst (enzyme) for desired reaction design the basic biocatalytic process
- Syllabus
- 1. Opening Lecture 2. Introduction to Enzyme Technology 3. Basics of Enzymes as Biocatalysts 4. Kinetics of Enzyme Catalysed Reaction 5. Principles and Application of Enzyme Selectivity 6. Enzymes in Organic Synthesis I. 7. Enzymes in Organic Synthesis II. 8. Enzyme Production and Purification 9. Engineering of Biocatalysts 10. Immobilization of Enzymes and Cells 11. Reaction Engineering and Process Technology 12. Biotechnology Informatics
- Literature
- Assessment methods
- written test in English
- Language of instruction
- English
- Further Comments
- The course is taught annually.
The course is taught: every week. - Teacher's information
- http://loschmidt.chemi.muni.cz/peg/
- Enrolment Statistics (recent)
- Permalink: https://is.muni.cz/course/sci/autumn2008/C8858