Information System of Masaryk University 

Course Information

C8140 Bioenergetics

Faculty of Science
Spring 2008 - for the purpose of the accreditation

Extent and Intensity

2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Alternate Types of Completion: k (colloquium).

Teacher(s)

prof. RNDr. Igor Kučera, DrSc. (lecturer)

Supervisor

prof. RNDr. Igor Kučera, DrSc.
Department of Biochemistry - Chemistry Section - Faculty of Science
Contact Person: prof. RNDr. Igor Kučera, DrSc.

Prerequisites

C4182 Biochemistry II || C3580 Biochemistry
Basic courses in biochemistry and physical chemistry are recommended.

Course Enrollment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

Fields of study the course is directly associated with

there are 20 fields of study the course is directly associated with, display

Course objectives

An advanced lecture. Energy conservation in living organisms - overview and thermodynamics. Stucture and function of membrane enzymes. Electron transport in respiratory chains and during photosynthesis. Evolution of bioenergetic processes. Bioenergetics and ecology.

Syllabus

• 1) History and the present status of bioenergetics. Energy conversions in living organisms: an overview and thermodynamic description. 2) Macroergic compounds. Mechanisms of substrate-level energy conservation. 3) Biomembranes: lipids, proteins and their mutual interactions. Determination of the structure of membrane-bound proteins. 4) Mechanisms of membrane transport. Transporters, channels, ionophores. Membrane-bound transport ATPases. Rotational catalysis in the proton-translocating ATPase. 5) Enzymes, prosthetic groups and electron carriers involved in important redox reactions. 6) Membrane-bound electron-transport chains. Approaches to the study of the electron-transport chains. Artificial electron donors and acceptors. The coupling of redox reaction with proton gradient formation. 7) Isolation, ultrastructure and metabolic activities of mitochondria. Transport of proteins, inorganic ions and metabolites across the mitochondrial membrane. 8) Mitochondrial respiration and oxidative phosphorylation. 9) Aerobic respiration in chemoorganotrophic and chemolithotrophic bacteria. 10) Anaerobic respiration. Regulation mechanisms in facultative anaerobes. 11) Bacteriorhodopsin-based photosynthesis. Anoxygenic and oxygenic photosynthesis dependent on (bacterio)chlorophyll, cooperation of two photosystems in oxygenic photosynthesis. 12) Metabolic cooperation of mitochondria, chloroplasts and cytoplasm. 13) Mechanochemical energy conversions. Thermogenesis in brown fat tissue. Bioluminiscence. Bioenergetics of sodium ion. 14) Evolution of bioenergetic processes. Bioenergetics and the cycles of biogenic elements in the nature.

Literature

• DADÁK, Vladimír and Igor KUČERA. Nové poznatky z bioenergetiky (Recent advances in bioenergetics). Praha: Státní pedagogické nakladatelství, 1988. 128 pp. skriptum. info
• PEUSNER, Leonardo. Základy bioenergetiky. 1. vyd. Bratislava: Alfa, 1984. 277 s. info
• FERGUSON, Stuart J. and David G. NICHOLS. Bioenergetics 2. 1st ed. pub. London: Academic Press, 1992. 255 s. ISBN 0-12-518124-8. info
• KUČERA, Igor. Řešené úlohy z bioenergetiky (Solved problems from bioenergetics). Praha: Státní pedagogické nakladatelství, 1985. 151 pp. info

Assessment methods (v češtině)

Jde o jednosemestrovou přednášku s výukou 2 hod týdne. U zkoušky (kolokvia) si student vylosuje trojici otázek, z nichž jedna je zaměřena na kvantitativní aspekty předmětu. Nejprve má vyhrazenu 1 hod na zpracování písemné přípravy, pak následuje pohovor.

Further comments (probably available only v češtině)

The course is taught annually.
The course is taught: every week.

Listed among pre-requisites of other courses

• C8150 Bioenergetics - seminar
  NOW(C8140)  

Teacher's information

Student by měl získat ucelenou představu o hlavních typech energetických přeměn v živých buňkách, s důrazem na mechanismy spřažení chemických, resp. fotochemických procesů s transportem přes biologické membrány. Měl by být rovněž schopen zdůvodnit volbu experimentální metody vhodné ke studiu konkretního bioenergetického problému.

The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2002, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, spring 2012, spring 2012 - acreditation, spring 2013, spring 2014.

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• Enrollment Statistics (Spring 2008 - for the purpose of the accreditation, recent)
  
• Permalink: https://is.muni.cz/course/sci/spring2008-forthepurposeoftheaccreditation/C8140

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