The course is offered to students of any study field.
The concept of this course is introduction into the very complex science like vaccinology and related disciplines. The aim of this course is to obtain basic information and general knowledge about application fields of immunology for prevention and treatment of infectious diseases and cancer. The stress is put on showing the main connection between various scientific disciplines like e.g. immunology, biochemistry, genetics, molecular biology, chemistry and physical-chemistry, material sciences, pharmacology, human and veterinary medicine, etc. Some sociological, historical and political aspects of vaccination are introduced to complete the view of this field.
At the end of the course students should be able to understand and explain principles of various types of vaccines and immunotherapeutical aproaches, apply information on pathogen and its interaction with the host for suggestion of efficient strategy for development of particular vaccine or immunotherapy.
Historical, social, legislative and ethic aspects of immunotherapy and vaccination, vaccination strategies, anti-vaccination movement.
Literature – books and journals.
Veterinary and human vaccination campaign, vaccination programs. Epizootology and transfer of pathogens, examples of human and veterinary diseases. Mucosal immunity and its relation to vaccination
Antimicrobial peptides of natural and synthetic origin, antiviral drugs.
Mechanisms of immune response towards antigens.
Vaccines – live and attenuated, recombinant, subunit and genetic vaccines, adjuvans, nano- and microcarriers (polymers, liposomes, dendrimers, microbubles).
Cell therapy and cell-based vaccines.
Immunogenetics, immunopharmacology, neuroimmunology.
KREJSEK, Jan and Otakar KOPECKÝ. Klinická imunologie. 1. vyd. Hradec Králové: NUCLEUS HK, 2004. 941 s. ISBN 80-86225-50-X. info
Veterinární imunologie. Edited by Miroslav Toman. 1. vyd. Praha: Grada, 2000. 413 s. ISBN 80-7169-727-3. info
HOŘEJŠÍ, Václav and Jiřina BARTŮŇKOVÁ. Základy imunologie. 3. vyd. Praha: Triton, 2005. 279 s. ISBN 80-7254-686-4. info
JANEWAY, Charles A. Immunobiology :the immune system in health and disease. 6th ed. New York, N.Y.: Garland Science, Taylor & Francis Group, 2005. xxiii, 823. ISBN 0-8153-4101-6. info
Lectures and presentations by Czech specialists.
The stress is put on preparation of short lecture (10-15 min, Power-Point) on complex immunological/pharmaceutical/medicinal topics, clear and well focussed presentation (Czech, English and Slovak languages are acceptabel) and short discussion.