Bi7042 Immunology of viral infections

Faculty of Science
Spring 2025
Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
RNDr. Jiří Salát, Ph.D. (lecturer)
prof. RNDr. Daniel Růžek, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Daniel Růžek, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: Mgr. et Mgr. Michal Dvořák
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites
Bi5420 General virology && Bi5220 Immunology
The lectures are suitable for students of biological disciplines interested in virology.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of the course is to gain information about immune response during viral infections. The lectures contain also information about methodical procedures for immune mechanisms assessment and abut vaccines against viral infections.
Learning outcomes
Students will be able describe and discuss following topics: Immune processes during viral infections, Methods for immune mechanisms description, Vaccines against viruses.
Syllabus
  • Immune mechanisms (summary introduction);
  • Recognition of viruses on molecular level (extracellular and intracellular mechanisms of recognition);
  • Cell-intrinsic defences (role of apoptosis, necrosis, autophagy);
  • Interferon system and antiviral action; Innate immunity and viral infection;
  • Adaptive immunity (cell mediated) and viral infection;
  • Adaptive immunity (humoral) and viral infection;
  • Selected methods for description of immune response against viral infection;
  • Modulation of immune response by viruses;
  • Vaccines against viruses;
  • Tick borne encephalitis virus - study of immune response and development of vaccines.
Literature
    recommended literature
  • BRAMHACHARI, P.V. Dynamics of Immune Activation in Viral Diseases. Springer Singapore, 2020. ISBN 978-981-15-1045-8. info
  • FLINT, J. Principles of Virology. American Society for Microbiology, 2020. ISBN 1-68367-284-4. info
  • MAK, Tak W. and Mary E. SAUNDERS. The immune response : basic and clinical principles. Amsterdam: Elsevier, 2006, xx, 1194. ISBN 0120884518. URL info
Teaching methods
Lectures with presentation projection.
Assessment methods
Written test and oral exam.
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
  • Permalink: https://is.muni.cz/course/sci/spring2025/Bi7042