Biochemistry I
VSBC021s, ZLBC021s


               Spring 2009

SEMINARY CLASSES                   2nd Semester 2009


Week

Date


1

16. 2. – 20. 2.

Introduction into the metabolism of cells (differences between prokatyotic and eukaryotic cell,
compartmentation of metabolic processes, enzyme markers of cell fractions, non-covalent
interactions in the cell and their significance).


2

23. 2. – 27. 2.


Structure of haemoglobin and its relationship to the function. Hb types in the blood    of healthy
subjects, HbCO and MetHb, abnormal Hb types.


3

2. – 6. 3.


Enzymes - reaction rate, progress curve, the Michaelis plot and K[m], enzyme inhibition.


4

9. – 13. 3.


Coenzymes, their relationship to vitamins.

5

16. – 20. 3.


Written test I (Biochemical methods, haemoglobin, enzymology, coenzymes.)

Membrane structure and assembly. Transport across membranes.


6

6.týden

23. – 27. 3.


Metabolism of glucose: Glycolysis under anaerobic and aerobic conditions and the oxidation of
pyruvate. Gluconeogenesis. Glycogenesis and glycogenolysis.


7

30. 3.  – 3. 4.


Metabolism of proteins. Common features of amino acid conversion.

The synthesis of urea. Nitrogen balance.


8

6. – 10. 4.


Important reactions in amino acid catabolism.

9

14. – 20. 4.


Written test II (Membranes, transport across membranes, metabolism of saccharides and amino acids.)

Biosynthesis and desaturation of fatty acids. The sources of essential fatty acids. Metabolism of
triacylglycerols.


10

10.týden

21. – 27. 4.


Metabolism of phospholipids. Biosynthesis of eicosanoids. Peroxidation of lipids.

11

28. 4. – 4. 5.


Written test III (Metabolism of lipids.)

The citric acid cycle.


12

5. – 11. 5.


The respiratory chain and oxidative phosphorylation.


13

12. - 18. 5.




Credit test for the students who did not reach the required result in preceding tests.

14

19. – 25. 5.

Compensatory lessons, consultation. Credits.

15

25. 5. – 29. 5.

(Anatomical dissection course.)


Students are expected to come to the seminary room at least 5 minutes before the start of the
lesson.

Attendance in seminars is obligatory.

All absences must be justified through the Department of study affairs up to 5 days.  Illness is
usually the only acceptable excuse for absence from class and must be officially confirmed. After
being absent the student must make up for the study materials from the given seminar according to
the teachers instructions.


Neglected lessons have to be made up by 19. 6.  2009.


Conditions for giving the course-unit credit


The first condition is full (100%) attendance in the all seminars.

Three short tests are written during the semester. Students that will obtain 70% points or more
during the semester are not obliged to write the credit test.

The other students will write the credit test with the 30 questions in the last week of the
semester. The limit for passing the credit test is 12 points. Students that will not fulfill this
limit will be allowed to repeat the test once. Remedial dates for writing the credit test will be
scheduled till 19.6.2009. Students that will not fulfill this requirement will not be given the
course-unit credit.


Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to
the examination of Biochemistry I.