Ist Institute of Pathology – Stomatology General Pathology incl. General Oncology 1. Methods of pathology: Biopsy, cytology incl. clinical implications 2. Methods of pathology: Autopsy 3. Histological and other special techniques 4. Disease and its causes 5. Death and postmortal changes 6. Necrosis, apoptosis 7. Atrophy 8. Agenesis/aplasia, atresia, hypoplasia, ectopia including examples. Chromosomal abnormalities and single gene alterations including examples. 9. Cystic fibrosis/mucoviscidosis. Inborn storage disorders. 10. Amyloidosis. 11. Pathology of pigments and pigmentations, incl. icterus 12. Pathologic calcifications, stones 13. Pathology of nutrition. Consequences of malnutrition and obesity. 14. Hypertrophy, hyperplasia 15. Regeneration, reparation 16. Metaplasia, dysplasia 17. Oedema 18. Hyperemia, venous congestion 19. Focal disorders of blood supply, ischemia, infarction 20. Haemorrhage. 21. Thrombosis, embolism 22. Shock 23. Heart failure - types, causes, complications 24. Causes and course of inflammation 25. Inflammation – general microscopic and macroscopic changes 26. Classification and morphologic patterns of inflammation 27. Granulomatous inflammation 28. Immune system and its functions 29. Immune reactions 30. Transplantation 31. Primary and secondary immunodeficiency incl. HIV 32. Autoimmune diseases 33. Mechanisms of bacteria and virus-induced injury 34. Skin infections 35. Respiratory system infections 36. Gastrointestinal system infections 37. Genitourinary system infections 38. Nervous system infections 39. Injury by physical and chemical agents, incl. environmental pollution 40. Ageing and death 41. Definitions, preneoplastic lesions, pseudotumors 42. Classification of tumors, grading and staging of tumors 43. Structure, growth of tumors, invasion and metastases 44. Intraepithelial neoplasia, carcinoma in situ 45. Carcinogenesis, etiology of tumors 46. Effects of tumor on host 47. Mesenchymal tumors excl. haematopoietic neoplasms 48. Neoplastic disorders of bone marrow 49. Malignant lymphomas 50. Tumors of the superficial epithelium 51. Tumors of the glandular epithelium 52. Neuroendocrine tumors 53. Neuroectodermal tumors of the NS 54. Tumors of melanocytes 55. Mixed tumors, germinal tumors 56. Choriocarcinoma, mesothelioma II. Systematic Pathology incl. Systematic Oncology 1. Congenital and acquired heart diseases 2. Pericardial diseases, endocarditis 3. Myocardial diseases incl. ischemic heart disease 4. Hypertension 5. Atherosclerosis and other arterial regressive changes 6. Vascular diseases incl. inflammatory 7. Pathology of the veins and lymphatic vessels. 8. Tumors of the heart + vessels. Pathology of the spleen and the thymus incl. tumors 9. Non-neoplastic lymphadenopathy 10. Anaemia 11. Disorders of blood coagulation and haemostasis 12. Pathology of the upper respiratory tract incl. tumors 13. Vascular disease of the lungs 14. Obstructive airways disease 15. Interstitial lung diesease 16. Infections of the lower respiratory tract 17. Lung tumors 18. Pathology of the pleura incl. tumors 19. Pathology of the esophagus incl. tumors 20. Pathology of the stomach incl. tumors 21. Developmental and vascular intestinal disorders, malabsorption 22. Inflammatory intestinal diseases incl. infections 23. Pathology of the peritoneum, obstructive disease, ileus 24. Neoplasms of the small and large intestine 25. Metabolic and circulatory disorders of the liver 26. Acute a chronic liver disease 27. Liver cirrhosis, tumors of the liver 28. Pathology of the extrahepatic biliary tract incl. tumors 29. Pathology of exocrine pancreas incl. tumors 30. Kidney – congenital and vascular diseases, cysts 31. Glomerular diseases 32. Tubulointerstitial disorders incl. nephritis 33. Pathology of the urinary tract 34. Tumors of the kidney and urinary tract 35. Pathology of the male genital tract incl. tumors 36. Pathology of the external female genital tract incl. tumors 37. Pathology of the uterine corpus incl. tumors 38. Pathology of the fallopian tubes and ovaries incl. tumors 39. Pathology of the pregnancy 40. Inflammations, proliferative disorders and benign tumors of the breast 41. Malignant tumors of the breast 42. Cerebrovascular disease, CNS trauma 43. Congenital defects, age related defects, degenerative disorders incl. dementia. 44. CNS infections, demyelinating and metabolic disorders 45. Intracranial tumors 46. Pathology of the peripheral nervous system, the eye and the ear, incl. tumors 47. Pathology of the pituitary, diffuse endocrine system (incl. neuroendocrine neoplasias/carcinoids) 48. Pathology of the thyroid and parathyroid glands, incl. tumors 49. Pathology of the endocrine pancreas and adrenal glands, incl. tumors 50. Pathology of the bone incl. tumors 51. Pathology of the joints 52. Pathology of the connective tissue and muscle incl. tumors 53. Infections and non-infectious inflammatory lesions of the skin 54. Eczema/dermatitis, bullous disorders, ulcers. Pathology of the skin adnexa 55. Skin tumors and pseudotumorous lesions III. Oral Pathology: 1. Disorders of development of teeth (number, size, form). 2. Disorders of development of teeth (structure) and cranofacial anomalies 3. Non-odontogenic cysts of the jaws and oral soft tissues, including developmental cysts 4. Odontogenic cysts 5. Postnatal and acquired abnormalities of teeth 6. Dental caries – aetiology and immunology 7. Dental caries - pathology 8. Disorders of dental pulp 9. Periapical diseases 10. Periodontal diseases 11. Physical and chemical injuries of the oral mucosa. 12. Bacterial, protozoal infections of the oral mucosa 13. Fungal, viral infections of the oral mucosa 14. Oral ulceration, vesiculobullous and dermatologic diseases 15. Oral manifestation of systemic diseases and other disorders of oral mucosa 16. Hematologic disorders, allergic and immunologic diseases 17. Hyperplastic disorders of oral mucosa; melanocytic lesions and malignant melanoma 18. Keratoses and precancerous (or premalignant) lesions and conditions 19. Oral epithelial tumors 20. Salivary gland pathology excl. tumors 21. Salivary gland tumors 22. Odontogenic tumors 23. Soft tissue tumors and lesions 24. Non-neoplastic bone pathology 25. Bone tumors 26. Diseases of the temporomandibular joints; neuromuscular diseases