AMOLp Introduction into molecular biology and genetics - lecture

Faculty of Medicine
Spring 2016
Extent and Intensity
2/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 11:10–12:50 B11/334
Prerequisites
(! VSBI0222p Biology II-lect. ) && (! ZLBI0222p Biology II -lect. ) && (! PřF:Bi1700 Cell Biology )
Knowledge of high school biology
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects. Student is also able to apply this knowledge and skills in following subjects.
Syllabus
  • Introduction. Biopolymers I - proteins.
  • Biopolymers II - nucleic acids and DNA replication.
  • Bacteria and viruses.
  • Architecture and function of eukaryotic cell.
  • From gene to protein - expression of genetic information.
  • Principles of intercellular communication and adhesion. Cell differentiation.
  • Mitosis and cytokinesis. Meiosis.
  • Cell cycle and its regulation. Cell death.
  • Malignant transformation of cells.
  • Principles of heredity I.
  • Principles of heredity II. Molecular diagnostics.
  • Gonosomal and multifactorial heredity. Mutations. Mechanisms of DNA repair.
  • Stem cells and strategy of molecular therapy.
  • Human genome and gene engineering. Gene therapy.
Literature
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
    recommended literature
  • NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
Teaching methods
two-hour lecture per week
Assessment methods
The course is completed with a written exam test containing 60 questions. In one ne half of the test questions student choses between yes/no (without negative marking). The other half of the test questions offers 4 possible answers, where 1 to all answers can be correct (negative marking applies for incorrect answers). To pass the exam, 30 points are needed (out of 60). The test is based on knowledge of all topics from lectures and practices.
Succesfull passing of the courses's practice is required for attending the exam.
Attendance at the lectures is optional.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on course enrolment limitations: Student nesmí mít absolvovaný ani současně zapsaný předmět Biologie II na LF, ani předmět Bunečná biologie Bi1700 na PřF.
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2016/AMOLp/index.qwarp
The course is also listed under the following terms Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (Spring 2016, recent)
  • Permalink: https://is.muni.cz/course/med/spring2016/AMOLp