BLLC0111p Medical Chemistry-lecture

Faculty of Medicine
autumn 2020
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Taught online.
Teacher(s)
doc. RNDr. Jiří Dostál, CSc. (lecturer)
prof. RNDr. Eva Táborská, CSc. (lecturer)
doc. RNDr. Josef Tomandl, Ph.D. (lecturer)
MUDr. Michaela Králíková, Ph.D. (assistant)
RNDr. Hana Paulová, CSc. (assistant)
Mgr. Jiří Slanina, Ph.D. (assistant)
Mgr. Marie Tomandlová, Ph.D. (assistant)
Guaranteed by
doc. RNDr. Josef Tomandl, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable
Mon 13:00–14:50 B11/334
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of the course students have knowledge that is necessary for understanding of chemical principles applied in further study subjects, especially in biochemistry.He/she understand solution properties and basic physico-chemical laws. Describes the properties of elements and inorganic compounds important for medicine, nutrition and toxicology. Discuses the structure of compounds and reactions taking part in metabolism and organic compounds that have importance in toxicology.
Learning outcomes
Students will be able to:
- understand basics of general, inorganic and organic chemistry to the extent necessary for the further study of biochemistry.
- apply general physicochemical laws to processes in living organisms.
- describe the chemical properties of the most important biogenic elements and essential compounds of importance in medicine, nutrition and toxicology.
- describe and discuss the properties and reactions of organic and bioorganic compounds important for the understanding of biochemical processes
Syllabus
  • Dispersion systems. Coligative properties. Osmotic pressure. Colloid solutions. Surfactants.
  • Electrolytes, activity of ions, ionic strength. Acid-base reactions, pH, hydrolysis of salts, buffers.
  • Chemical thermodynamics, bioenergetics. Chemical kinetics.
  • Redox reactions, redox potentail, relation to Gibbs energy. Biochemially important redox systems. Solubility of salts, precipitacion reactions.
  • Biologically important elements and their compounds.
  • Biological important reactions of organic compounds (alcohols, citrate cycle, transaminations).
  • Biologically important heterocyclic compounds.
  • Structure and properties of monosaccharides, disaccharides.
  • Homopolysaccharides. Heteropolysaccharides.
  • Fatty acids, triacylglycerols, phospholipids, glycolipids.
  • Steroids. Steroid hormones. Calciols. Eicosanoids.
  • Amino acids, polarity, biochemicalké conversions.
  • Proteins, structure. Examples of globular, fibrous, membrane proteins. Glycoproteins, hemoproteins.
  • Nucleosides. Nucleotides. Nucleis acids.
Literature
Teaching methods
Lectures.
Assessment methods
Written examination consisting of two parts.
  • The first part is solved electronically: calculations of concentration, pH, osmotic pressure / osmolarity, simple questions requiring one-word answers or selection from the offered answers, recognition / naming of the mentioned compounds.
  • The second part is written: active drawing of structural formulas and equations, active answers to three thematic areas (general and inorganic chemistry, organic chemistry, static biochemistry). The questions concern the relevant chemical principles and their understanding.
    • Language of instruction
    Czech
    Follow-Up Courses
    Further comments (probably available only in Czech)
    Information on completion of the course: přistoupení ke zkoušce je podmíněno úspěšným ukončením předmětů BLLC0111s a BLLC0111c.
    The course is taught annually.
    Information on the extent and intensity of the course: 30.
    Listed among pre-requisites of other courses
    The course is also listed under the following terms Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2021, autumn 2022, autumn 2023.
    • Enrolment Statistics (autumn 2020, recent)
    • Permalink: https://is.muni.cz/course/med/autumn2020/BLLC0111p