EMBI0121s Biologie I - seminář

Faculty of Medicine
autumn 2021
Extent and Intensity
1/0/0. 3 credit(s). Type of Completion: z (credit).
Taught in person.
Teacher(s)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
Mgr. Kateřina Francová, Ph.D. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (assistant)
Jana Růžičková (assistant)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Francová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Thu 14. 10. to Tue 2. 11. Tue 10:00–10:50 B11/234, Tue 16. 11. to Tue 14. 12. Tue 10:00–10:50 B11/234; and Tue 14. 9. 10:00–10:50 F01B1/122, Tue 21. 9. 10:00–10:50 B11/234, Tue 5. 10. 10:00–10:50 F01B1/309, Tue 9. 11. 10:00–10:50 F01B1/309
Prerequisites
Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_CZ.qwarp) or similar, and knowledge of all previous lectures of the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recommended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding of cellular and molecular biology with a special focus on the potential application of acquired knowledge in clinical medicine
Learning outcomes
After completing the course the student will be able to: • - describe and explain the organization of prokaryotic and eukaryotic genome, DNA replication • - explain elementary processes taking place in cells (gene expression, inter- and intra-cellular communication, cell differentiation, cell division, cell death) and their purposes • - explain the relationship between malfunctioning of cellular processes and development of diseases • - explain how gene mutations and chromosome aberrations cause human diseases, and illustrate it with examples
Syllabus
  • Introduction to the Medical Biology
  • Chemical nature of life – chemical components of cells, protein structure and function
  • Architecture and function of eukaryotic cell I – structure and function of biomembranes, organelles
  • Architecture and function of eukaryotic cell II – nucleus, cytoskeleton
  • Genome organization - nucleic acids, chromosome structure, DNA replication
  • Genome stability and instability – DNA damage, mutations, DNA repair and defects in DNA repair
  • Gene expression I - central dogma of molecular biology, gene structure, transcription, genetic code, translation
  • Gene expression II – regulation of gene expression, cell differentiation
  • Cellular Communication – General Principles of Cell Signalling, Receptors, Signalling Pathways
  • Cell Cycle and Principles of its Regulation
  • Cell Divison – Mitosis and Meiosis
  • Cell Death
  • Cells and Tissue – Cell Junctions, Adhesive Molecules and Extracellular Matrix
Literature
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing. xxvi, 630. ISBN 8090290620. 2004. info
  • D. Peter Snustad Michael J. Simmons. Genetika. Brno. ISBN 9788021086135. 2017. info
Teaching methods
seminar every week
Assessment methods
Credit will be awarded at the end of autumn semester (based on full attendance; one excused absence is allowed). Biology I is continued with Biology II which is completed with an test.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Information on the extent and intensity of the course: 15.
Teacher's information
https://is.muni.cz/auth/el/med/podzim2021/EMBI0121s/index_sgzlw.qwarp
Seminars take place every week and are compulsory. We recommend to follow the Interactive syllabus of the course where students can find all relevant information (schedule, substitutions, public holidays etc.), and also corresponding study literature for each week, and links to animations and videos relevant to the topic (https://is.muni.cz/auth/el/1411/podzim2021/EMBI0121p/index.qwarp)


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