EMEM0933p Embryology

Faculty of Medicine
autumn 2024

The course is not taught in autumn 2024

Extent and Intensity
2/0/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. MVDr. Aleš Hampl, CSc. (lecturer)
PharmDr. Zuzana Holubcová, Ph.D. (lecturer)
MUDr. Eva Mecová (seminar tutor)
Drahomíra Kyjovská (assistant)
Guaranteed by
doc. MVDr. Aleš Hampl, CSc.
Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine
Prerequisites
EMEM0832p
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of this course is for students to gain a thorough understanding of the biology of peri- and post-implantation development, including factors influencing the course of pregnancy.
Learning outcomes
Graduates of the course will: - - - have a comprehensive and thorough overview of the biology of implantation and post-implantation development - - be able to critically analyse and interpret scientific findings and also assess their relevance to clinical practice - - be able to statistically analyse scientific and clinical data and assess the quality of statistical evaluation.
Syllabus
  • - embryonic hatching, formation of multiple gestation, endocrine and paracrine signaling during implantation, embryo and endometrium interaction, role of immunological tolerance - - hormonal control of the menstrual cycle, cyclic endometrial changes, decidualization and vascularization, implantation window - - trophoblast invasion, placental formation and function, pathology of implantation, trophoblastic disease, molar pregnancy - - endometrial receptivity and selectivity, implantation failure and early pregnancy loss, ectopic pregnancy, chimerism and microchimerism, first trimester risk factors - -gastrulation, differentiation of the three germ layers, review of organogenesis, causes of miscarriage - -experimental models of peri- and post-implantation development, ex-utero organogenesis - - clinical reproductive immunology - importance, types of investigations, effect of autoimmune diseases on fertility - - reproductive endocrinology - effect of endocrine conditions on fertility and course of pregnancy - - hematology of reproduction - pre-eclampsia, HELLP syndrome, thrombotic complications of pregnancy - - endometriosis - - interspecies reproductive differences, use of assisted reproductive techniques in veterinary medicine - - biostatistics - study design, data analysis, advanced statistical analysis of clinical data
Literature
    recommended literature
  • Dekner HW, Aplin J: Trofoblast Invasion and Endomerial Receptivity. 1st ed. New York 1990.
  • Critchley H, Cameron I, Smith S: Implantation and Early Development. 1st ed. London 2005.
Teaching methods
lecture + seminars The condition for admission to the exam is participation in 1) lectures by external lecturers and 2) the course of biostatistics
Assessment methods
written exam
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
Information on the extent and intensity of the course: 30.
  • Permalink: https://is.muni.cz/course/med/autumn2024/EMEM0933p