LF:VLBI0222c Biology II-pract. - Course Information

VLBI0222c Biology II - practice

Faculty of Medicine
spring 2020

Extent and Intensity

0/3/0. 3 credit(s). Type of Completion: z (credit).

Teacher(s)

Guaranteed by

prof. MUDr. David Šmajs, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

VLBI0222c/01: Mon 17. 2. to Mon 11. 5. Mon 12:30–13:00 B07/205a, Mon 13:00–14:30 B07/217, Mon 13:00–14:30 B07/205a, Mon 14:30–15:00 B07/205a
VLBI0222c/02: Mon 17. 2. to Mon 11. 5. Mon 12:30–13:00 B07/205a, Mon 13:00–14:30 B07/217, Mon 13:00–14:30 B07/205a, Mon 14:30–15:00 B07/205a
VLBI0222c/03: Mon 17. 2. to Tue 12. 5. Tue 8:30–9:00 B07/205a, Tue 9:00–10:30 B07/217, Tue 9:00–10:30 B07/205a, Tue 10:30–11:00 B07/205a
VLBI0222c/04: Mon 17. 2. to Tue 12. 5. Tue 8:30–9:00 B07/205a, Tue 9:00–10:30 B07/217, Tue 9:00–10:30 B07/205a, Tue 10:30–11:00 B07/205a
VLBI0222c/05: Mon 17. 2. to Wed 13. 5. Wed 11:30–12:00 B07/205a, Wed 12:00–13:30 B07/205a, Wed 12:00–13:30 B07/217, Wed 13:30–14:00 B07/205a
VLBI0222c/06: Mon 17. 2. to Wed 13. 5. Wed 11:30–12:00 B07/205a, Wed 12:00–13:30 B07/205a, Wed 12:00–13:30 B07/217, Wed 13:30–14:00 B07/205a
VLBI0222c/07: Mon 17. 2. to Thu 14. 5. Thu 11:00–11:30 B07/205a, Thu 11:30–13:00 B07/217, Thu 11:30–13:00 B07/205a, Thu 13:00–13:30 B07/205a
VLBI0222c/08: Mon 17. 2. to Thu 14. 5. Thu 11:00–11:30 B07/205a, Thu 11:30–13:00 B07/217, Thu 11:30–13:00 B07/205a, Thu 13:00–13:30 B07/205a
VLBI0222c/09: Mon 17. 2. to Wed 13. 5. Wed 14:30–15:00 B07/205a, Wed 15:00–16:30 B07/205a, Wed 15:00–16:30 B07/217, Wed 16:30–17:00 B07/205a
VLBI0222c/10: Mon 17. 2. to Wed 13. 5. Wed 14:30–15:00 B07/205a, Wed 15:00–16:30 B07/217, Wed 15:00–16:30 B07/205a, Wed 16:30–17:00 B07/205a
VLBI0222c/11: Mon 17. 2. to Mon 11. 5. Mon 15:30–16:00 B07/205a, Mon 16:00–17:30 B07/205a, Mon 16:00–17:30 B07/217, Mon 17:30–18:00 B07/205a
VLBI0222c/12: Mon 17. 2. to Mon 11. 5. Mon 15:30–16:00 B07/205a, Mon 16:00–17:30 B07/217, Mon 16:00–17:30 B07/205a, Mon 17:30–18:00 B07/205a
VLBI0222c/13: Mon 17. 2. to Thu 14. 5. Thu 14:00–14:30 B07/205a, Thu 14:30–16:00 B07/205a, Thu 14:30–16:00 B07/217, Thu 16:00–16:30 B07/205a
VLBI0222c/14: Mon 17. 2. to Thu 14. 5. Thu 14:00–14:30 B07/205a, Thu 14:30–16:00 B07/217, Thu 14:30–16:00 B07/205a, Thu 16:00–16:30 B07/205a
VLBI0222c/15: Mon 17. 2. to Fri 15. 5. Fri 9:00–9:30 B07/205a, Fri 9:30–11:00 B07/217, Fri 9:30–11:00 B07/205a, Fri 11:00–11:30 B07/205a
VLBI0222c/16: Mon 17. 2. to Fri 15. 5. Fri 9:00–9:30 B07/205a, Fri 9:30–11:00 B07/205a, Fri 9:30–11:00 B07/217, Fri 11:00–11:30 B07/205a
VLBI0222c/17: Mon 17. 2. to Thu 14. 5. Thu 8:00–8:30 B07/205a, Thu 8:30–10:00 B07/217, Thu 8:30–10:00 B07/205a, Thu 10:00–10:30 B07/205a
VLBI0222c/18: Mon 17. 2. to Thu 14. 5. Thu 8:00–8:30 B07/205a, Thu 8:30–10:00 B07/205a, Thu 8:30–10:00 B07/217, Thu 10:00–10:30 B07/205a

Prerequisites (in Czech)

VLBI0121c Biology I -pract. && VLBI0121s Biology I - seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

General Medicine (programme LF, M-VL) (2)

Course objectives

The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practising the selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to the selection of appropriate therapy

Learning outcomes

After completing the course the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counselling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene
- explain the basic laboratory tests used in genetic toxicology and the overall use of genetic toxicology, and to interpret the results obtained by selected methods

Syllabus

Week 1: Genetic disorders - gonosomal inheritance
Week 2: Extensions to basic genetics
Week 3: Genetic prognosis and genetic counselling
Week 4: Human population genetics
Week 5: Molecular diagnostics of cancer with respect to treatment options - odd groups; Control test 3 - even groups (knowledge from week 13 of the autumn semester to week 4 of the spring semester - lectures, seminar, practices)
Week 6: Molecular diagnostics of cancer with respect to treatment options - even groups; Control test 3 - odd groups (knowledge from week 13 of the autumn semester to week 4 of the spring semester - lectures, seminar, practices)
Week 7: Gene engineering – production of human proteins in bacterial cells - odd groups
Week 8: Gene engineering – production of human proteins in bacterial cells - even groups
Week 9: Molecular diagnostics of human pathogenic bacteria - odd groups
Week 10: Molecular diagnostics of human pathogenic bacteria - even groups
Week 11: Genetic toxicology
Week 12: substitution practices - substitutions for public holidays
Week 13: Control test 4 (knowledge from week 5 to week 12 of the spring semester - lectures, practices)
Week 14: dissection week – no practices
Week 15: dissection week – no practices

Literature

required literature

Protokoly ke cvičením jsou dostupné v elektronické podobě v Informačním systému MU ve Studijních materiálech předmětu VLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 12 points out of 20 in each test). In case you do not pass one of the control tests and its re-sit, you have to pass the final test (Credit test) based on knowledge of the entire semester lectures and practices. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for a written explanation. At least 10 points out of 20 are needed to pass.
In case of student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS. Bring the essay printed to the teacher who specified the topic, and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In the case of 4 or more unexcused absences, the course-unit credit is not awarded.

Language of instruction

Czech

Follow-Up Courses

Further comments (probably available only in Czech)

The course is taught annually.
Information on the extent and intensity of the course: 45.

Listed among pre-requisites of other courses

AMOLc Introduction into molecular biology and genetics - practice
(!VSBI0222c) && (!VLBI0222c) && (!ZLBI0222c) && !NOWANY(VLBI0222c,ZLBI0222c) && (!PřF:Bi1700c)
VLHE0322c Histology and Embryology II - practice
(VLHE0221c || VSHE0221c) && (VLBI0222c || VSBI0222c)
VLHE0322p Histology and Embryology II - lecture
(VLHE0221c || VSHE0221c) && (VLBI0222c || VSBI0222c)

Teacher's information

Interactive syllabus of the course:
Odd groups: https://is.muni.cz/auth/el/1411/jaro2020/VLBI0222c/index_liche.qwarp
Even groups: https://is.muni.cz/auth/el/1411/jaro2020/VLBI0222c/index_sude.qwarp

What to bring to each practice: printed protocol for the respective practice, your own writing materials. Download the protocol for each practice from the Study materials in the IS, and study it in advance. Lab shoes, lab coats and disposable gloves are not required, but for the tasks with staining, lab coats are recommended.

Substitution of practices: In exceptional cases (illness, appointment at the doctor’s or foreign policy, 1 or 2 times per semester as maximum) student can arrange a substitution with another group. To arrange a substitution, write an e-mail to the contact person of the course at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead. Substitution is only possible on the same teaching week. When the capacity of the group you intended to substitute with is fully used, the substitution does not need to be approved. Repeated substitution with other groups is not allowed.

Complete Biology instructions to be found at the following link: https://is.muni.cz/auth/el/1411/jaro2020/VLBI02020c/op/Pokyny_ke_cvicenim_z_Biologie.pdf

The course is also listed under the following terms Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2021, spring 2022, spring 2023, spring 2024.

Enrolment Statistics (spring 2020, recent)
Permalink: https://is.muni.cz/course/med/spring2020/VLBI0222c

LF:VLBI0222c Biology II-pract. - Course Information

VLBI0222c Biology II - practice

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