LF:aZLPF0622p Pathophysiology II - lecture - Course Information
aZLPF0622p Pathological Physiology II - lecture
Faculty of Medicinespring 2025
- Extent and Intensity
- 2/0/0. 3 credit(s). Type of Completion: zk (examination).
- Teacher(s)
- prof. MUDr. Anna Vašků, CSc. (lecturer)
prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MUDr. Michal Jurajda, Ph.D. (lecturer)
prof. MUDr. Kateřina Kaňková, Ph.D. (lecturer)
prof. RNDr. Michal Masařík, Ph.D. (lecturer)
prof. RNDr. Monika Pávková Goldbergová, Ph.D. (lecturer)
Bc. Lenka Hladíková (assistant)
prof. MUDr. Lydie Izakovičová Hollá, Ph.D. (assistant) - Guaranteed by
- prof. MUDr. Anna Vašků, CSc.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: prof. MUDr. Anna Vašků, CSc.
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine - Prerequisites (in Czech)
- aZLPF0521c Pathophysiol. I - practice && aZLBC0422p Biochemistry II - lecture && aZLFY0422p Physiology II - lecture
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Dentistry (programme LF, M-DENT)
- Dentistry (eng.) (programme LF, M-ZL)
- Course objectives
- The aim of the subject is to train students in dynamic thinking about etiology and pathogenesis of diseases focused on special pathophysiology themes:
Pathophysiology of cardiovascular system.
Pathophysiology of digestive system, nutrition deficits.
Pathophysiology of endocrine system, metabolic diseases.
Pathophysiology of hemopoietic system, neoplasias.
Rheumatic diseases. Immunologically conditioned diseases.
Pathophysiology of respiratory tract.
Pathofphysiology of kidneys, disturbances in metabolism of water and ions.
Pathophysiology of nervous system.
Pathophysiology of muscles and sensory organs. - Learning outcomes
- Student will be able:
- to explain the pharmacological options affecting the secretion of gastric juice in the context of experimentally induced gastric ulcer in experimental animal model (inhibition of proton pump, H2 receptor blockade);
- to explain the pharmacological options affecting the secretion of gastric juice in the context of experimentally induced gastric ulcer in experimental animal model (inhibition of proton pump, H2 receptor blockade);
- to demonstrate the principle of load test (oGTT) in an animal model of experimentally induced diabetes (alloxan);
- to identify clinically relevant parameters describe nutritional status (calorimetry, BMI, WHR index, the weight, the skin-fold thickness, bioimpedance, DEXA) ;
- todemnostrate the examination of the quality of the skin barrier, through the examination of resistance and conductivity of the skin or a chemical (Burckhardt´s) examination with regard to the composition of the skin barrier;
- to demonstrate onset of obstruction icterus induced by ligation of ductus choledochus. He understands etiopathogenesis of other types of icterus (hemolytic, hepatic) and diagnostics of them using heme metabolites in urine, blood and stool using mitochondrial/cytoplasmatic membranes liver enzymes;
- to describe etiopathogenesis of venous thrombosis using data from experimental animal model;
- to explain the importance and principles of DNA d iagnostics to detect I/D polymorphism using PCR methodology ACE - Literature
- required literature
- NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003, s. 381-760. ISBN 9788024606743. info
- NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003, 379 s. ISBN 9788024606750. info
- NEČAS, Emanuel a spol. Obecná patologická fyziologie. 1. vyd. Praha: Karolinum, 2000, 377 pp. ISBN 80-246-0051-X. info
- Teaching methods
- Lecture.
- Assessment methods
- Oral exam. The final exam is oral; student will answer 4 questions selected by lot from general, special pathophysiology, practicals and lectures. Individual evaluation from practicals (described by assistant) is taken into account.
- Language of instruction
- English
- Further comments (probably available only in Czech)
- The course is taught each semester.
The course is taught: every week.
Information on the extent and intensity of the course: 30. - Listed among pre-requisites of other courses
- aVLKB091 Clinical Biochemistry
aVLPF0622p ||aZLPF0622p - aZLDL0821p Pediatric Dentistry I - lecture
(aZLED061p || aZLKED061p) && (aZLES0711c ||aZLKZL072p) && aZLFA0722c && aZLOR0742c && aZLPL0764c && aZLPD0732c && aZLOC0754c && (aZLKZ051p || aZLKZL051p) && aZLOP0622p && aZLPA0622p && aZLPF0622p - aZLFT0811c Physiotherapy and Exercise Therapy Programme - practice
aZLPA0622p && aZLPF0622p && aZLLM0522p && aZLIP061p && aZLFA0722c - aZLFT0811p Physiotherapy and Exercise Therapy Programme - lecture
aZLPA0622p && aZLPF0622p && aZLLM0522p && aZLIP061p && aZLFA0722c - aZLKG0911s Bases of Clinical Genetics - seminar
aZLGE061p && aZLOR0843c && aZLPF0622p && aZLLM0522p && aZLPD0833c && aZLSP03X - aZLNE0811c Neurology - practice
aZLPA0622p && aZLPF0622p && aZLLM0522p && aZLIP061p && aZLFA0722c - aZLNE0811p Neurology - lecture
aZLPA0622p && aZLPF0622p && aZLLM0522p && aZLIP061p && aZLFA0722c - aZLOL0811c Ophthalmology - practice
aZLPA0622p && aZLPF0622p && aZLLM0522p && aZLIP061p && aZLFA0722c - aZLPY0911c Psychiatry - practice
aZLPF0622p && aZLFA0722c && aZLNE0811c && aZLCH0833c && aZLIP061p && aZLSP03X
- aVLKB091 Clinical Biochemistry
- Enrolment Statistics (spring 2025, recent)
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