FaF:F1FO1_13 Dosage Forms and Biopharmacy - Course Information
F1FO1_13 Dosage Forms and Biopharmacy I
Faculty of PharmacyAutumn 2023
- Extent and Intensity
- 3/6/0. 5 credit(s). Type of Completion: z (credit).
Taught in person. - Teacher(s)
- doc. PharmDr. Aleš Franc, Ph.D. (lecturer)
doc. PharmDr. Kateřina Kubová, Ph.D. (lecturer)
doc. PharmDr. Ruta Masteiková, CSc. (lecturer)
PharmDr. Kateřina Tenorová, Ph.D. (seminar tutor)
doc. PharmDr. Jan Gajdziok, Ph.D. (lecturer)
PharmDr. Miroslava Pavelková, Ph.D. (lecturer)
PharmDr. Jakub Vysloužil, Ph.D. (lecturer)
Mgr. Dagmar Blaháčková (seminar tutor)
Mgr. Daniela Hlavatá (seminar tutor)
Mgr. Gabriela Koutná (seminar tutor)
PharmDr. Andrea Peštálová (seminar tutor)
Mgr. Lucie Pizúrová (seminar tutor)
Mgr. Veronika Podkalská (seminar tutor)
PharmDr. Lucie Sedláčková (seminar tutor)
Mgr. Martin Veselý (seminar tutor)
PharmDr. Jiří Zeman, Ph.D. (seminar tutor) - Guaranteed by
- doc. PharmDr. Kateřina Kubová, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Contact Person: doc. PharmDr. Kateřina Kubová, Ph.D.
Supplier department: Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy - Timetable
- Thu 12:50–15:20 44–056
- Timetable of Seminar Groups:
F1FO1_13/02: Mon 13:00–14:40 18-122, Mon 14:40–18:00 18-107, K. Kubová, L. Sedláčková
F1FO1_13/03: Tue 7:30–9:10 18-122, Tue 9:10–12:30 18-138, L. Pizúrová, J. Vysloužil
F1FO1_13/05: Tue 13:00–14:40 18-122, Tue 14:40–18:00 18-138, J. Gajdziok, M. Veselý
F1FO1_13/06: Tue 13:00–18:00 18-107, A. Peštálová
F1FO1_13/07: Wed 7:30–9:10 18-122, Wed 9:10–12:30 18-138, V. Podkalská, K. Tenorová
F1FO1_13/08: Wed 7:30–12:30 18-107, D. Hlavatá, J. Zeman
F1FO1_13/09: Wed 13:00–14:40 18-122, Wed 14:40–18:00 18-138, A. Franc
F1FO1_13/10: Wed 13:00–18:00 18-107, D. Blaháčková - Prerequisites (in Czech)
- FAKULTA ( FaF ) || OBOR ( MUSFaF )
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
The capacity limit for the course is 160 student(s).
Current registration and enrolment status: enrolled: 97/160, only registered: 0/160 - fields of study / plans the course is directly associated with
- Pharmacy (programme FaF, M-FARM)
- Multidisciplinary studies at Faculty of Pharmacy (programme CST, KOS)
- Vzdělávání v jednotlivých předmětech (programme FaF, C-CV)
- Course objectives
- Pharmaceutical technology is a fundamental discipline within the pharmaceutical field. The course aims to introduce students to compounding, industrial production, and quality control of medications, including excipients, technological procedures, equipment, and appropriate analytical devices. Additionally, it covers the impact of the drug's application form on its bioavailability within the organism.
- Learning outcomes
- Upon successful completion of the course, students will be able to:
- theoretically know the classification, requirements, excipients, technological procedure of preparation and production of liquid dosage forms and their evaluation (solutions, emulsions, suspensions)
- theoretically know the classification, requirements, excipients, and technological procedure for the preparation and manufacture of ophthalmic, nasal, and ear preparations and their evaluation
- theoretically know the classification, requirements, excipients, and technological procedure for the preparation and manufacture of parenteral preparations and their evaluation
- theoretically know the classification, requirements, excipients, and technological procedure for the preparation and manufacture of semi-solid dosage forms and their evaluation (ointments, pastes, creams, gels)
- to determine the basic aspects of dosage forms in relation to the bioavailability of the drug
- to perform essential calculations (concentrations, doses, mixing equations, ratios, etc.)
- to check the doses of a drug in a medicinal product according to the prescription of the product according to Pharmacopoeia
- to prepare both pharmacopoeial and non-pharmacopoeial solutions, syrups, aromatic waters, suspensions, emulsions, eye drops, nasal drops, and ear drops skillfully
- to detect fundamental incompatibilities in the composition of individually formulated medicinal products
- to determine the shelf life of individually formulated medicinal products
- to select suitable packaging options for individually formulated medicinal products
- to estimate the optimal storage conditions required for individually formulated medicinal products - Syllabus
- SYLLABUS OF LECTURES
1. Introduction into Medical Forms and Biopharmacy. Solutions: basic methods of preparation, quality evaluation.
2. Public holiday
3. Sterilization techniques. Requirements for the preparation of sterile medications.br>4. Ophthalmic preparations - definition, classification, preparation, quality evaluation, the bioavailability of drugs from ophthalmic products.
5. Preparations intended for nasal and ear application.
6. Pharmaceutical emulsions - definition, classification, preparation, quality evaluation. Physical aspects of emulsions.
7.Pharmaceutical suspensions - definition, classification, preparation, quality evaluation.
8. Incompatibilities in liquid dosage forms.
9.Excipients for preparation of liquid dosage forms (solutions). Water for pharmaceutical purposes.
10. Herbal drug preparations - definition, classification, preparation and production, quality assessment.
11. Parenteral dosage forms.
12. Topical semisolid preparations: definition, classification, properties, excipients.
13. Topical semisolid preparations: preparation and quality evaluation.
PRACTICAL TRAINING
1. Introduction to the practical training. Pharmaceutical calculations.
2. Medicinal solutions: preparation at room and higher temperature, evaluation.
3. Medicinal solutions: preparation by solubilization and chemical reaction, evaluation. Test - Pharmaceutical calculations.
4. Aromatic waters and spirits. Syrups. Infusions and decoctions. Mucilagines. Preparation and evaluation.
5. Eye drops. Preparation and evaluation.
6. Nasal and ear drops. Preparation and evaluation.
7. Consultation exercise on liquid dosage forms.
8.Emulsions. Preparation and evaluation. Test - calculations for eye and nasal medicinal products.
9. Suspensions. Preparation and evaluation. Test - emulsifiers.
10. Preparation of liquid dosage forms according to prescriptions.
11. Alternative training.
12. Credit test and testing of laboratory skills.
13. Awarding credits.
- SYLLABUS OF LECTURES
- Literature
- Teaching methods
- Lectures
Lab training
Homework - Assessment methods
- Intermediate tests in laboratory classes (3 tests, two retakes are possible)
Systematic observation of the student during laboratory classes, preparation of reports following the teacher's instructions
Credit test (credit test has two parts, part 1 - pharmaceutical calculations (limit for passing 75%), part 2 - test - closed and open questions (especially opened) from knowledge from lectures and laboratory classes (limit for passing - 60%).
Practical testing is conducted to evaluate students' skills as part of the credit assessment. (preparation of the medicinal product - detection of incompatibilities, control of dosage, selection of the correct procedure, selection of appropriate packaging, correct labelling of the product - shelf life, storage conditions). - Language of instruction
- Czech
- Follow-Up Courses
- Further comments (probably available only in Czech)
- The course can also be completed outside the examination period.
- Listed among pre-requisites of other courses
- Teacher's information
- Lectures are recommended due to lack of suitable literature.
Laboratory classes are obligatory (100 %).
Credit for courses will only be awarded where a student will:
- participate in 100% of lab part of the course (maximum in two cases, individual laboratory classes can be done later - alternative class according to syllabus)
- complete successfully three tests during semester
- complete successfully credit test in the end of the course
- complete successfully testing of laboratory skill in the end of the course.
- Enrolment Statistics (recent)
- Permalink: https://is.muni.cz/course/pharm/autumn2023/F1FO1_13