F1VG1_13 Advanced Drug Delivery

Faculty of Pharmacy
Spring 2020
Extent and Intensity
1/2/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. PharmDr. Kateřina Kubová, Ph.D. (lecturer)
doc. PharmDr. Ruta Masteiková, CSc. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
doc. PharmDr. Jan Gajdziok, Ph.D. (seminar tutor)
doc. PharmDr. Kateřina Kubová, Ph.D. (seminar tutor)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (seminar tutor)
PharmDr. Jakub Vysloužil, Ph.D. (seminar tutor)
Guaranteed by
doc. PharmDr. Kateřina Kubová, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Prerequisites (in Czech)
Absolvování předmětu Lékové formy a biofarmacie I
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
This eligible subject introduces sophisticated dosage forms with modified drug release based on the present knowledge in biopharmacy and pharmacokinetics. It deals with special technological approaches of their manufacturing and special control methods ensuring their quality.
Syllabus
  • SYLLABUS OF LECTURES
    1.Introduction in advanced drug delivery. Matrix tablets.
    2.Multiparticular dosage forms: pellets and their production technologies and their use in pharmacotherapy.
    3.Ocular therapeutic systems.
    4. Colonic drug delivery systems.
    5. Implants
    6. Modern vaginal systems.
    7. Modern transdermal systems.
    Syllabus of practical training
    1.Preparation of dosage forms of matrix type and their evaluation.
    2.Preparation of pellets using extrusion/spheronization and their evaluation by dissolution test.
    3. ------------------------
    4. Preparation of pellets using rotoagglomeration and their evaluation.
    5. Preparation of pellets by drug solution layering on inactive pellets. Preparation od reservoir-type dosage form with controlled drug release.
    6. Methods for technological parameters evaluation (microscopic analysis, sieve analysis, density, mechanical properties, dissolution methods for drug release testing, etc.)
    7. The preparation of microparticles and ionic gelation by solvent evaporation.
Literature
    recommended literature
  • Komárek, P., Rabišková, M. Technologie léků. Galén, Praha, 2006. ISBN 80-7262-423-7. info
    not specified
  • Česká a slovenská farmacie. info
  • Praktické lékárenství. info
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
oral examination
pacticipation on all practical trainings required
The course is also listed under the following terms Spring 2021, Spring 2022, Spring 2023.
  • Enrolment Statistics (Spring 2020, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2020/F1VG1_13