FaF:FAAC1_15 General and Inorganic Chemistr - Course Information
FAAC1_15 General and Inorganic Chemistry
Faculty of PharmacyAutumn 2021
- Extent and Intensity
- 3/3/0. 8 credit(s). Type of Completion: zk (examination).
Taught in person. - Teacher(s)
- PharmDr. Tomáš Goněc, Ph.D. (lecturer)
Mgr. Aleš Kroutil, Ph.D. (lecturer)
PharmDr. Tomáš Goněc, Ph.D. (seminar tutor)
Mgr. Aleš Kroutil, Ph.D. (seminar tutor) - Guaranteed by
- PharmDr. Tomáš Goněc, Ph.D.
Department of Chemical Drugs – Departments – Faculty of Pharmacy - Timetable
- Mon 14:10–16:40 44-247
- Timetable of Seminar Groups:
- Prerequisites (in Czech)
- FAKULTA ( FaF ) || OBOR ( MUSFaF )
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Multidisciplinary studies at Faculty of Pharmacy (programme CST, KOS)
- Pharmacy (programme FaF, M-FARMA)
- Course objectives
- The students will be acquainted with the subject of chemistry including the basic branches of chemistry and the importance of chemistry for pharmacists. The course will focus on the following items: fundamental chemical terms and laws, equations for calculating the quantity of substance and concentration, atomic structure, radioactivity, models of atomic orbitals, chemical bond including hybridization, physical states of matter, the periodic law and the classification of elements including forms and the division of the periodic system into groups, and the properties of individual elements in the periodic table.
Seminars will concentrate on problems such as calculating the amount of substance, composition of solutions, diluting and mixing solutions, formation of chemical formulas and balancing equations for stoichiometric calculations, and the calculation of the pH. During practical exercises, the students will be acquainted with the basics of laboratory work and will also prepare some inorganic compounds according to calculated equations. The students will elaborate protocols containing the description of the principle of the method and all calculations including the calculation of theoretical yield which will be compared with the practical yield obtained. - Learning outcomes
- After completing the course student will:
-know basic chemical glassware,equipment and apparatus;
-be able to perform basic laboratory operations independently;
-know inorganic compound nomenclature and basic chemical clculations;
-understand the basic principles of general chemistry;
-know basic chemistry of elements - Syllabus
- Lectures:
General Chemistry.
Role of the chemistry in the spectrum of naturae sciences. History of chemistry. Mass, discreetness of particles. Elements, symbols, periodic table, molecule, chemical formula, chemical equation. Structure and electron formula, octet rule, hypervalence, resonance, oxidation state, formal charge. Electronegativity. Definition of element, nuclide, isotope. Atomic number, atomic mass, molecular mass, amount of mass, mol. Atom, nucleus, elemental particles of mass. Moseley rule. Radioactivity, natural and artificial radionuclides, nuclear reactions, decay families.
Quantum and wave theory, wave and particle, interference and difraction. Schrödinger equation. Planetar atom model, electron shell, Bohr model of hydrogen atom, line and continual spectra, therms, hydrogen spectrum. Structure of electron shell, quantum nombers, Pauli rule, Hund rule, stable valence shell configuration, excited state, electron configuration writing. Mendelejev periodic rule. Ionization potential, electron affinity, electronegativity. Atomic orbitals.
Chemical bond, forms of bonding, bonding energy. Covalent bond. Valence bonding theory, simple and multiple bonds. VSEPR. Hybridization.
Molecule orbitals theory (MO) - linear combination of atomic orbitals (LCAO), energetic diagram. MO for: H2, N2, O2 and O3. Delocalized bonds, polarised bond. System of bonds in ethene, ethyne, benzene and allene.
Hydrogen bonds, other weak interactions. Ionization, basic ion properties, ionic bond. Crystals. Metalic bond. Electron conductivity. Donor-acceptor bond, ions of transition metals, coordinational reactions, sorts of ligands and their properties. Coordination bonding theory. Structure, magnetic properties.
Chemical ballance, basic thermodynamical and thermochemical laws, state equations. Entalpy, entropy, free energy, spontaneousness of processes. Floating ballance principle. Basics of chemical kinetics. Speed and order of reaction. Activation energy. Arrhenius equation. Catalysis. Radical reactions. Photochemical reactions.
Base and acid theories, protolytic reactions, neutralisation, salts, strenght of acid and base, pH, indicators, salts hydrolysis, buffers. Lewis theory, electrophiles and nucleophiles. Coagulation. Factor of solubility. Reduction-oxidation reactions. Ballancing of red-ox equations. Electrode processes. Electrochemical potential.
Inorganic chemistry.
Chemistry of hydrogen, water. Alkalic metals, metals of alkaline earths.
P elements,Halogens, Noble gases. Transition elements.
Inorganic compounds important in biosystems and pharmacy.
Practical class
- Introduction to laboratory work
- Purification of benzoic acid
- Distillation and extraction
- Synthesis of trihydrogen boric acid.
- Synthesis of disodium tetrahydroxo pentaoxoborate.
- Synthesis of lead iodide.
- Preparation od copper and ferrous sulphate pentahydrate.
- Preparation of ferric oxide
Seminars
- Nomenclature of inorganic compounds
- Solutions concentration calculations
- Chemical equations, Stoichometry, Acidobasic equilibria
- electron structure, shape of molecules, Lewis formulas
- Lectures:
- Literature
- Teaching methods
- seminars (nomenclature and calculations), laboartory courses, lectures
- Assessment methods
- To obtain credits, it is necessary to meet the following conditions: compulsory participation in seminars and laboratory courses, the obligation to prepare protocols from all practical tasks. Success in continuous tests in nomenclature and calculations at least 60%. Written test exam consist of three parts: nomenclature and calculations, general chemistry and inorganic chemistry. To pass the exam at lest 5O% correct answers is necessary.
- Language of instruction
- English
- Further comments (probably available only in Czech)
- Study Materials
The course can also be completed outside the examination period. - Teacher's information
- How to get the credit and grade for this course:
Students must pass the lab portion of the course in order to pass the entire course.
The requirements for the lab portion:
Attendance of practical class is compulsory. Non-attendance can be compensated at the end of the semester. One or two practicals will be replaced by seminar, which will be focused on calculations based on previous test results. Also these seminars are compulsory.
Requirements for gaining the credit:
- full attendance in all practicals and seminars,
- to hand in all protocols from all practical tasks in accepted form
- at least 60% successfulness in the tests the overall successfulness will be calculated as an average of all tests results,
The exam:
The exam will be written and the test will consist of two parts:
1. Computational problems from general chemistry similar to problems that were
dealt with in the tutorial
For this part are only simple scientific calculators permitted, no mobile phones or any
other material.
2. Questions from general and inorganic chemistry.
To answer this part of the test you may use presentations, textbooks or your notes from the lecture. Using mobile phones or any electronic devices is not allowed.
The duration of each part will be 90 minutes.
Any form of academic dishonesty (e.g., cheating, deception, fabrication, plagiarism,
sabotage, etc.) will result in the test percentage of 0% .
To determine the final grade in this course the percentage will be converted to a letter grade
according to the following grading scheme:
100 90 % A excellent
89 80 % B very good
79 70 % C good
69 60 % D satisfactory
49 50% E sufficient
< 49 % F fail
- Enrolment Statistics (Autumn 2021, recent)
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