FaF:FAFO2_13 Medical Forms and Biopharmacy - Course Information

FAFO2_13 Medical Forms and Biopharmacy II

Extent and Intensity

3/6/0. 11 credit(s). Type of Completion: zk (examination).

Teacher(s)

doc. PharmDr. Aleš Franc, Ph.D. (lecturer)
doc. PharmDr. Jan Gajdziok, Ph.D. (lecturer)
doc. PharmDr. Kateřina Kubová, Ph.D. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
PharmDr. Jakub Vysloužil, Ph.D. (lecturer)
doc. PharmDr. Aleš Franc, Ph.D. (seminar tutor)
doc. PharmDr. Jan Gajdziok, Ph.D. (seminar tutor)
doc. PharmDr. Kateřina Kubová, Ph.D. (seminar tutor)
PharmDr. Jakub Vysloužil, Ph.D. (seminar tutor)

Guaranteed by

doc. PharmDr. Kateřina Kubová, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy

Prerequisites

Obligatory subject: DOSAGE FORMS AND BIOPHARMACY
Academic year: 2014/2015, term 8th, year 4th
Extent: 9 hours per week
Form:
Lectures: 3 hours
Practical training: 6 hours
SYLLABUS OF LECTURES
1 Development of new drugs from galenical perspective
lecturer: Dr. Aleš Franc, Ph. D.
2 Validation in pharmaceutical technology
lecturer: Dr. Aleš Franc, Ph.D.
3 Semisolid dosage forms - creams, gels, pastes
lecturer: Dr. Martina Kejdušová, Ph.D.
4 Dosage forms for rectal application.
lecturer: Dr. Kateřina Dvořáčková, Ph.D.
5 Dosage forms for vaginal application.
lecturer: Dr. Kateřina Dvořáčková, Ph.D.
6 Pharmaceutical incompatibilities in dosage forms.
lecturer: Dr. Martina Kejdušová, Ph.D.
7 Tablets, their production, and evaluation.
lecturer: Dr. Aleš Franc, Ph.D.
8 Coated products, their production and evaluation.
lecturer: Dr. Jan Gajdziok, Ph.D
9 Capsules, their production and evaluation.
lecturer: Dr. Kateřina Dvořáčková, Ph.D.
10 Oral dosage forms with controlled drug release.
lecturer: Dr. Martina Kejdušová, Ph.D.
11 Regulatory authorities evaluation of dosage forms
lecturer: Ass. Prof. David Vetchý, Ph.D.
12 Transdermal preparations, their production and evaluation.
lecturer: Dr. Kateřina Dvořáčková, Ph.D.
13 Pharmaceutical aerodispersions.
lecturer: Dr. Jan Gajdziok, Ph.D

PRACTICAL TRAINING
1. Ointments. Preparation and evaluation.
2. Creams. Preparation and evaluation.
3. Pastes and gels. Preparation and evaluation
4. Rectal suppositories. Determination of base replacement coefficient, calculations, preparation of suppositories with known base replacement coefficient.
5. Rectal suppositories. Experimental determination of base replacement
coefficient. Preparation of suppositories with unknown base replacement coefficient.
6. Vaginal dosage forms. Preparation and evaluation.
7. Incompatibilities in liquid, semisolid and solid dosage forms.
8. Calculations in pharmaceutical technology.Technological processes in preparation of difficult prescriptions.
9. Alternative training.
10. Tablets preparation by direct compression.
11. Fluid bed granulation method.
12. Wet and melt granulations.
13. Evaluation of solid dosage forms.
14. Test and check training.

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Pharmacy (programme FaF, M-FARMA)

Course objectives

One of the main obligatory pharmaceutical disciplines dealing with preparation, manufacturing and quality control of medicaments including technological procedures, equiment, excipients and appropriate analytical devices. It covers the influence of the application form on drug bioavailability.

Syllabus

• SYLLABUS OF LECTURES
  1. Semisolid dosage forms - ointments lecturer: Dr. Jakub Vysloužil, Ph.D.
  2. Semisolid dosage forms - creams, gels, pastes lecturer: Dr. Jakub Vysloužil, Ph.D.
  3. Dosage forms for rectal application.lecturer: Associate prof. Dr. Kateřina Kubová, Ph.D.
  4. Dosage forms for vaginal application. lecturer: Associate prof. Dr. Kateřina Kubová, Ph.D.
  5. Pharmaceutical incompatibilities in dosage forms. lecturer: Associate prof. Dr. Kateřina Kubová, Ph.D.
  6. ---------------
  7. Granules, granulation methods. Evaluation of powders and granules.lecturer: Associated prof. Dr Jan Gajdziok, Ph.D
  8. Tablets, their production, and evaluation.lecturer: Associated prof. Aleš Franc, Ph.D.
  9. Coated products, their production and evaluation.lecturer: Associate prof. Dr. Jan Gajdziok, Ph.D
  10. Oral dosage forms with controlled drug release.lecturer: Dr. Jakub Vysloužil, Ph.D.
  11. Pharmaceutical aerodispersions.lecturer: Associate prof. Dr. Jan Gajdziok, Ph.D
  12. Validation in pharmaceutical technology lecturer: Dr. Aleš Franc, Ph.D.
  13. Regulatory authorities evaluation of dosage forms lecturer: Associate prof. Dr. et Mgr. David Vetchý, Ph.D.
  14. Development of new drugs from galenical perspectivelecturer: Associated prof Aleš Franc, Ph. D.
  SYLLABUS OF LABORATORY PRACTICE
  1. Ointments. Preparation and evaluation.
  2. Creams. Preparation and evaluation.
  3. Pastes and gels. Preparation and evaluation.
  4. Rectal suppositories. Determination of base replacement coefficient, calculations, preparation of suppositories with known base replacement coefficient.
  5. Rectal suppositories. Experimental determination of base replacement coefficient. Preparation of suppositories with unknown base replacement. coefficient.
  6. Alternative training.
  7. Vaginal dosage forms. Preparation and evaluation.
  8. Incompatibilities in liquid, semisolid and solid dosage forms. Calculations in pharmaceutical technology.
  9. Technological processes in preparation of difficult prescriptions.
  10. Wet and melt granulations.
  11. Tablets preparation by direct compression.
  12. Evaluation of solid dosage forms.
  13. Fluid bed granulation method.
  14. Test and check training.
  
  

Literature

recommended literature
• European Pharmacopoeia 9. Online info
• The texts which are available during the lectures.. Online info
• Handbook of Pharmaceutical Excipients. Online. Great Britain, 2006. ISBN 1-58212-058-7. [citováno 2024-04-24] info

Language of instruction

English

Further comments (probably available only in Czech)

The course can also be completed outside the examination period.

Teacher's information

Lectures are recommended due to the lack of appropriate literature.
Practical training - compulsory.
oral examination

• Enrolment Statistics (Spring 2020, recent)
  
• Permalink: https://is.muni.cz/course/pharm/spring2020/FAFO2_13