FAFO2_13 Dosage Forms and Biopharmacy II

Faculty of Pharmacy
Spring 2023
Extent and Intensity
3/6/0. 11 credit(s). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
doc. PharmDr. Aleš Franc, Ph.D. (lecturer)
doc. PharmDr. Jan Gajdziok, Ph.D. (lecturer)
doc. PharmDr. Kateřina Kubová, Ph.D. (lecturer)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
PharmDr. Jakub Vysloužil, Ph.D. (lecturer)
doc. PharmDr. Aleš Franc, Ph.D. (seminar tutor)
doc. PharmDr. Jan Gajdziok, Ph.D. (seminar tutor)
doc. PharmDr. Kateřina Kubová, Ph.D. (seminar tutor)
PharmDr. Jakub Vysloužil, Ph.D. (seminar tutor)
PharmDr. Miroslava Pavelková, Ph.D. (seminar tutor)
PharmDr. Kateřina Tenorová, Ph.D. (seminar tutor)
PharmDr. Jiří Zeman, Ph.D. (seminar tutor)
Guaranteed by
doc. PharmDr. Kateřina Kubová, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Timetable
Thu 9:15–11:45 18-122
  • Timetable of Seminar Groups:
FAFO2_13/01: Thu 12:30–14:00 18-122, Thu 14:00–17:30 18-107, A. Franc, J. Gajdziok, K. Kubová, M. Pavelková, K. Tenorová, J. Vysloužil, J. Zeman
FAFO2_13/02: No timetable has been entered into IS.
Prerequisites
FAFO1_13 Dosage Forms and Biopharmacy
Dosage Forms and Biopharmacy I
Students can study this course only after completing the course Dosage Forms and Biopharmacy I
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 20 student(s).
Current registration and enrolment status: enrolled: 4/20, only registered: 0/20
fields of study / plans the course is directly associated with
Course objectives
One of the main obligatory pharmaceutical disciplines dealing with preparation, manufacturing and quality control of medicaments including technological procedures, equiment, excipients and appropriate analytical devices. It covers the influence of the application form on drug bioavailability.
Learning outcomes
After completing the course, student will: - theoretically know the classification, requirements, excipients, technological process of preparation and production of solid dosage forms, including their evaluation; - theoretically know the classification, requirements, excipients, technological process of preparation and production of dosage forms with controlled drug release, including their evaluation; - know the basic aspects of dosage forms in relation to the drug bioavailability - practically know the preparation of semisolid and solid dosage forms in pharmacy conditions;
Syllabus
  • Topic of lecture

    Granules, granulation methods. Evaluation of powders and granules
    Dosage forms for rectal application
    Dosage forms for vaginal application
    Tablets, their production, and evaluation
    Coated products, their production and evaluation
    Pharmaceutical incompatibilities in dosage forms
    Dosage forms with controlled drug release
    Pharmaceutical aerodispersions
    Transdermal preparations
    Validation in pharmaceutical technology
    Regulatory authorities evaluation of dosage forms
    Development of new drugs from galenical perspective
    Good manufacturing practice in pharmacy

    Practical labs

    Semisolid dosage forms - ointments
    Semisolid dosage forms - creams
    Semisolid dosage forms - pastes, gels
    Rectal and vaginal dosage forms - theoretical aspect of preparation, calibration coefficient
    Preparation of rectal suppositories
    Preparation of vaginal globules
    Incompatibilities in liquid, semisolid and solid dosage forms - theoretical aspect of preparation
    Technological processes in preparation of difficult prescriptions
    Alternative training
    Wet and melt granulations
    Tablets preparation by direct compression
    Evaluation of solid dosage forms
    Fluid bed granulation
    Credit test
Literature
    required literature
  • The texts which are available during the lectures. info
  • KUBOVÁ, Kateřina, Aleš FRANC, Jan GAJDZIOK, Martina KEJDUŠOVÁ and David VETCHÝ. Medical forms and biopharmacy - II. Solid Dosage Forms. Brno: Farmaceutická fakulta Veterinární a farmaceutické univerzity, 2014, 87 pp. skripta. ISBN 978-80-7305-757-2. URL info
    recommended literature
  • European Pharmacopoeia 9. info
  • Handbook of Pharmaceutical Excipients. Great Britain, 2006. ISBN 1-58212-058-7. info
Teaching methods

1Lectures
2Lab training
3 Homework
Assessment methods

1.Written credit test
2.Systematic observation of student during lab training
3.Practical test of student skills
3.Oral examination
Language of instruction
English
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
Lectures are recommended due to the lack of suitable literature. Students can study this course only after completing the course Dosage Forms and Biopharmacy I
All study materials are available in IS MU.
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2022, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2023, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2023/FAFO2_13