FaF:FAFT1_14 Pharmacology I - Course Information
FAFT1_14 Pharmacology I
Faculty of PharmacySpring 2021
- Extent and Intensity
- 3/3/0. 7 credit(s). Type of Completion: z (credit).
Taught online. - Teacher(s)
- doc. PharmDr. Peter Kollár, Ph.D. (lecturer)
PharmDr. Tereza Kauerová, Ph.D. (seminar tutor)
doc. PharmDr. Peter Kollár, Ph.D. (seminar tutor) - Guaranteed by
- doc. PharmDr. Peter Kollár, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy - Timetable
- each odd Monday 9:00–10:30 44-249, each odd Monday 16:00–17:30 44-249, each odd Monday 17:30–19:30 44-249
- Timetable of Seminar Groups:
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
The capacity limit for the course is 24 student(s).
Current registration and enrolment status: enrolled: 1/24, only registered: 0/24 - fields of study / plans the course is directly associated with
- Multidisciplinary studies at Faculty of Pharmacy (programme CST, KOS)
- Pharmacy (programme FaF, M-FARMA)
- Course objectives
- Pharmacology is a science that studies interactions of medical substances and organisms on various morphological and physiological levels. It focuses on mechanisms and time progress of medicines in organisms (pharmacokinetics), and on medicines impact mechanisms on an organism (pharmacodynamics). Certain toxicology sections (science on toxins) constitute a part of the pharmacology in the area of undesirable effects as well.
Course contents: The course is divided into general pharmacological principles and special pharmacology, i.e. into drug groups classified according to their influence on the functional systems of the organism (pharmacodynamic agents). - Learning outcomes
- After completing the course the student is able to clarify the basic general rules regarding the fate of the drug in the body and the mechanisms of the drug's effect on the human body. Student can also define and characterize the properties of specific drugs - mechanisms of action, pharmacological effects, pharmacokinetic properties, side effects and interactions. The student will be able to apply the acquired knowledge about the properties of drugs in a safe and effective pharmacotherapy.
- Syllabus
- General pharmacology
Pharmacokinetics
- Types of drug transport (translocation) in organism
- Absorption of drugs, influencing factors
- Distribution of drugs in organism, influencing factors
- Distribution - physiological barriers
- Metabolism of drugs, influencing factors
- Mechanisms of drugs excretion, influencing factors
- Basic pharmacokinetic parameters, calculation, practical significance in pharmacotherapy
- Factors influencing pharmacokinetics
Pharmacodynamics
- Mechanisms of drugs action
- Quantitative (graded) and quantal (population) dose (concentration)- response relationships.
- Therapeutic index
- Drugs interactions
- Adverse and toxic effects of drugs
- Drug dependence, basic types
- Preclinical testing of drugs
- Clinical testing of drugs
- Pharmacology and human genome (pharmacogenomics, gene therapy)
Special Pharmacology
Pharmacology of the peripheral nervous system
- Autonomic nervous system - muscarinic agonists (parasympathomimetics). Inhibitors of cholinesterase
- Autonomic nervous system - muscarinic antagonists (parasympatholytics)
- Autonomic nervous system - adrenoceptor agonists (sympathomimetics)
- Autonomic nervous system - adrenoceptor antagonists (sympatholytics)
- Neuromuscular-blocking drugs
- Local anaesthetics
Pharmacology of cardiovascular system
- Pharmacotherapy of chronic heart failure
- Antidysrhythmic drugs
- Pharmacotherapy of coronary heart disease: Therapy of angina pectoris. Overview of therapy of acute myocardial infarction
- Vasoactive drugs
- Inhibitors of angiotensin-converting enzyme. Antagonists of angiotensin receptors AT1
- Pharmacotherapy of arterial hypertension
- Pharmacology of the kidney
- Diuretics
- Atherosclerosis and lipoprotein metabolism
- Atherosclerosis risk factors, pharmacological and non-pharmacological prevention
- Pharmacotherapy of dyslipidaemias
- Drugs acting on haemostasis and fibrinolysis
- Drugs acting on the haemopoietic system: Treatment of anaemia by iron, folic acid and vitamin B12. Overview of haemopoietic growth factors
- General pharmacology
- Literature
- Teaching methods
- lectures, seminars
- Assessment methods
- The criterion for passing the course is to fulfill the attendance requirement at seminars and then to pass the credit test. The condition for passing the credit test is to achieve at least 55% of the maximum possible number of points.
- Language of instruction
- English
- Further comments (probably available only in Czech)
- The course can also be completed outside the examination period.
- Listed among pre-requisites of other courses
- FAFT2_14 Pharmacology II
(fakulta(FaF) || obor(MUSFaF)) && FAFT1_14
- FAFT2_14 Pharmacology II
- Teacher's information
- Conditions for successful completion of the course and obtaining credits are as follows: 1. Complete all seminars (100% Attendance is necessary) (according to Article 9, Paragraph 6 of the MU Study and Examination Regulations). In the case of excused absence – compensation for the absence from seminars would be in the form of a seminar paper (range 2–3 pages of A4 format) on a topic identical to the topic of the seminar, which a student could not attend. In the case of a long-term serious absence, it will be dealt with individually. 2. To score at least 55% to pass the credit test.
- Enrolment Statistics (Spring 2021, recent)
- Permalink: https://is.muni.cz/course/pharm/spring2021/FAFT1_14