FAOB1_14 Biology

Faculty of Pharmacy
Autumn 2024
Extent and Intensity
2/2/0. 5 credit(s). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
MVDr. Jana Hložková, Ph.D. (lecturer)
MVDr. Jana Hložková, Ph.D. (seminar tutor)
doc. RNDr. Ladislava Bartošová, Ph.D. (lecturer)
doc. RNDr. Jan Hošek, Ph.D. (lecturer)
Mgr. Martina Dvořáková (seminar tutor)
PharmDr. Tomáš Hammer (seminar tutor)
Mgr. Jana Melicharová (seminar tutor)
MVDr. Lada Tlučhořová (seminar tutor)
Guaranteed by
doc. RNDr. Jan Hošek, Ph.D.
Department of Molecular Pharmacy – Departments – Faculty of Pharmacy
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy (50,00 %), Department of Molecular Pharmacy – Departments – Faculty of Pharmacy (50,00 %)
Prerequisites
FAKULTA ( FaF ) || OBOR ( MUSFaF )
No prerequisites are required.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of study is to extend the knowledge of biology and genetics obtained at secondary schools so that the students might obtain the necessary fundamentals for both the contents and terminology of these disciplines, on whose basis they could continue the study of applied biological disciplines taught at the Pharmaceutical Faculty. The study is aimed at the general, molecular and cellular aspects of biology, at evolutionary biology and at the fundamentals of genetics.
Learning outcomes
The output of the course is mastering the basic concepts, orientation in the basic topics of biology and mastering the basic techniques in practical exercises
Syllabus
  • Biology introduction to the subject, definition of the field, history, fields of biology, taxonomy, cell types Possibilities of imaging and imaging techniques in biology Membranes membrane structure (general features + viruses, prokaryotes, eukaryotes), transport across membranes diffusion, osmosis, transport proteins, ion channels and membrane potential, clinically important membranes Organelles, ER, GA, endosomes, lysosomes, peroxisomes, mechanisms of protein transfer into organelles, clinically important organelopathy General principles of intercellular communication in unicellular and multicellular organisms, signaling molecules, receptors associated with ion channels, G-proteins, enzymes, diseases of intercellular communication disorders Cell division - cell cycle (G1, S, G2, M), mitosis (prophase, prometaphase, metaphase, anaphase, telophase, cytokinesis), meiosis, cell cycle regulation Reproduction of organisms asexual reproduction (binary division, gemiparia, fisiparia, vegetative reproduction), sexual reproduction (spermiogenesis, oogenesis, fertilization), gametopathy Introduction to genetics gene, genome, genotype, phenotype, Mendelian genetics, non-Mendelian genetics, epigenetics, transcription, translation, prokaryotic genome, eukaryotic genome, genetic diagnostic tests in medicine (present history) Biology of the immune system (IS) - phylo and ontogenesis of IS, nonspecific and specific immunity, antigen, antibody, opsonization, MHC system, medically important immune disorders, transplant immunity, Interactions of living systems symbiosis, commensalism, infections (prions, viruses, bacteria, parasites) and the environment (ecotoxicology, environmental stress, GMO) Current topics in biomedical fields Credit procedure Practical excercises I. Microscopic technique 1. Work safety. 2. Organization of teaching, keeping protocols, conditions for granting credits 3. Working with a light microscope 4. Prokaryotic and eukaryotic cell structure. 5. Plant and animal cell structure. II. Prokaryota and protozoa 1. Prokaryota 2. Bacterial smear, Gram staining 3.Sacharomyces smear, staining. 4. Protozoa hay infusion, native preparation 5. Types of movements ciliary, amoeboid, flagellar 6. Staining and morphology of lactic acid bacteria, fixed preparation III. Mitosis 1. Preparation of mitotic preparation, staining 2. Mitotic index 3. Chromosomes of karyotype assembly IV. Meiosis 1. Spermatogenesis 2.Histology of seed-forming epithelium 3. Sperm morphology species differences 4. Oogenesis 5. Ovarian histology 6. Sex chromosomes 7. Detection of Bar's body, preparation of the specimen, staining V. Body structure of mammals 1. Anatomical body structure of a rodent autopsy, video 2. Histological structure of tissues and organs VI. Credit procedure 1. Substitute exercises. 2. Checking protocols. 3. Granting of credits.
Literature
    recommended literature
  • Bártová. BIOLOGY AND GENETICS THEORY FOR PRACTICALS. info
  • Gartner LP, Hiatt JL. Cell biology and histology 7th. ISBN 978-1-4511-8951-3. info
  • Alberts et al. Essential Cell Biology. GS Garland Science, Taylor and Francis Group, Ne. ISBN 0-8153-3481-8. info
  • Janisch R. Overview of general biology 3. Brno, 2015. ISBN 978-80-210-7927-4. info
Teaching methods
Lectures, discussion, practical lectures, demonstatration, Protocols
Assessment methods
Full participation in exercises is obligatory. This subject will be terminated by written test. In the case of failure the test students complete the subject by oral examination. Submission of all protocols is required
Language of instruction
English
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
Pass compulsory practicals, be successful in writing two tests during semester, to have in good order protocols, to obtain credit and be successful in final exam.
Activity Difficulty [h]
Domácí příprava na výuku 50
Příprava na zkoušku 50
Summary 100
The course is also listed under the following terms Autumn 2020, Autumn 2021, Autumn 2022, Autumn 2023.
  • Enrolment Statistics (Autumn 2024, recent)
  • Permalink: https://is.muni.cz/course/pharm/autumn2024/FAOB1_14