FDAAF_FAF Solid Phase Analysis

Faculty of Pharmacy
Spring 2020
Extent and Intensity
1/1/0. 25 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Jiří Dohnal, CSc., MBA (lecturer)
Guaranteed by
doc. Ing. Jiří Dohnal, CSc., MBA
Faculty of Pharmacy
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
By mastering methods and techniques of solid phase analysis and follow-up case studies, the student should have a solid base for solving real problems that can occur during the life cycle management in the pharmaceutical practice.
Syllabus
  • Solid State Analysis - is the latest pharmaceutical analysis discipline without which it would not be possible to determine the parameters of drug substances and, above all, solid pharmaceutical forms. Selection of the optimum solid form is a critical aspect of the development of active pharmaceutical ingredients and finished solid dosage forms.
    According to the principles of analytical techniques, attention is paid to spectral methods (near and middle infrared spectroscopy in the setup of DRIFT or ATR, SS NMR, etc.), diffraction methods (powder X-ray diffraction, laser diffraction, dynamic light scattering, Raman scattering), thermal methods (DSC, TGA, TSC), microscopic methods (optical microscopy and image analysis, electron microscopy) and surface study methods (porosimetry, IGC and DVS).
Literature
    required literature
  • Richard A. Storey, Ingvar Ymén. Solid State Characterization of Pharmaceuticals. 2011. ISBN 9781405134941. info
    recommended literature
  • DOHNAL, Jiří a BRUSOVÁ, Hana a GRAFNETTEROVÁ, Taťjana a GRÜNWALD. Moderní přístupy k farmaceutické analýze: 3. Farmaceutická analýza v pevné fázi. VFU Brno, 2009. ISBN 978-80-7305-075-7. info
    not specified
  • Zakrzewski, M. Zakrzewski. Solid State Characterization of Pharmaceuticals. Danbury, 2006. ISBN 1405134941. info
Teaching methods (in Czech)
Dialogická (diskuze, rozhovor, brainstorming)
Metody práce s textem (učebnicí, knihou)
Assessment methods (in Czech)
Ústní zkouška
Rozhovor
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
Teaching takes place through personal consultations and other educational activities recommended by the guarantor of the subject.
ActivityDifficulty [h]
Domácí příprava na výuku25
Domácí příprava na výuku25
Summary50

  • Enrolment Statistics (recent)
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