Bi5220 Immunology

Faculty of Science
Autumn 2002
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
MVDr. Mgr. Monika Dušková, Ph.D. (lecturer)
doc. RNDr. Alena Žákovská, Ph.D. (lecturer)
Guaranteed by
doc. RNDr. Alena Žákovská, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: doc. RNDr. Alena Žákovská, Ph.D.
Prerequisites
Lecture involves the following program: Immune system: 1.Cells and organs of the immunity 2.Immune response: antigens, structure, chemical properties, classification, presentation MHC structure, function, regulation, immunogenetics: genes displacement, polymorphism, genesis of diversity Antibodies: structure, chemical properties, functions, classes of antibodies, isotypes, allotypes, idiotypes 3.Model system of immunity Nonspecific immunity: complement: structure and function, accute phasis reactants, inflammation Phagocytosis: phases, cooperation of the phagocytosis with other components of the immune system 4.The mechanism of the hypersensitivity: 5.Cytokine and immunomodulators: 6.Immunoregulation: 7.Immunology of transplantation 8.Immunity and cancer 9.Immunotoxicology 10.Reactions of the antigens and antibodies
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Syllabus Immune system: 1.Cells and organs of the immunity - ontogenesis, phenotype, structure, function and activacion, signals receptors: 2.Immune response: antigens, structure, chemical properties, classification, presentation MHC structure, function, regulation, immunogenetics: genes displacement, polymorphism, genesis of diversity Antibodies: structure, chemical properties, functions, classes of antibodies, isotypes, allotypes, idiotypes T-cell receptors: structure, function and antigen binding, interaction of receptors with ligands: adhesive molecules, complement receptors, Fc receptors, transfer of signals Nonspecific immunity: complement: structure and function, accute phasis reactans, inflammation Phagocytosis: phases, cooperation of the phagocytosis with other components of the immune system 3.Model mechanism of immune reaction 4.The mechanism of the hypersensitivity: IgE mediated : early and late response IgG, IgA and IgM : mediated, opsonisation, complement binding Immune complexes: mediated Cells mediated: Others NK cells, killer cells after the lymphokine activation, skin basophile hypersensitivity 5.Cytokine and immunomodulators: cytokine : origin, structure, effect, receptor-place of effect, metabolism, regulation and gene activation inflammation regulators: origin, structure, effect, receptor-place of effect, metabolism and regulation 6.Immunoregulation: Toleration, clonal selection, inhibition, antigenic paralytic intracellular - interaction: help and inhibition (suprese) Idiotype network: inhibition and simulation Mechanism of auto-immunity 7.Immunology of transplantation 8.Immunity and cancer 9.Immunotoxicology 10.Immunomodulation Methods of immune system Literature review
Syllabus
  • Specifické a nespecifické mechanismy imunity Anatomie a buněčné prvky imunitního systému Imunitní odpověď Mechanizmy přecitlivělosti Cytokiny a imunomodulátory Imunoregulace Transplantační imunologie Imunologie nádorů Imunoterapie Základní metody imunologie přehled literatury pro bc. studium
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (Autumn 2002, recent)
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