Bi6000 Biomaterials and their interaction with cells and tissues

Faculty of Science
Spring 2025
Extent and Intensity
1/0/0. 1 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
Prof. Ing. Petr Humpolíček, Ph.D. (lecturer)
Mgr. Jiří Pacherník, Ph.D. (lecturer)
Guaranteed by
Mgr. Jiří Pacherník, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The students will acquaint with basic types of biomaterials, especially polymeric, and their interactions with living organisms. Emphasis will be put on the knowledge of factors influencing the interaction of the biomaterials with cells and the possibilities of modification of the key material properties. Using case studies, students will get an overview of methodical approaches of problem solving and overview of current state of knowledge in the field of biomaterial development and testing.
Learning outcomes
Students will be able to:
- define biomaterials and describe their interaction with living organism
- describe and understand biocompatibility tests
- suggest properties and application of biomaterials
Syllabus
  • Part 1: Examples of biomaterials and their use, definition of key concepts, types of biomaterials, surface and volume properties of biomaterials. Part 2: Biocompatibility testing methods, cellular mechanisms and key structures for targeted interaction with biomaterials, methods of material adjustments. Part 3: Case studies of research and development of biomaterials and their applications.
Literature
  • ROSEN, Yitzhak a Noel ELMAN. Biomaterials science: an integrated clinical and engineering approach. Boca Raton: CRC Press, c2012, 1 online zdroj (xii, 301, 4 s.). ISBN 978-1-4398-0405-6. Dostupné také z: http://search.ebscohost.com/login.aspx?direct=true
  • RUYS, Andrew J. Biomimetic biomaterials: structure and applications. Oxford: Woodhead Publishing, 2013, xxvi, 308. Woodhead Publishing series in biomaterials. ISBN 978-0-85709-416-2.
  • RATNER, B. D. Biomaterials science: an introduction to materials in medicine. 3rd ed. Amsterdam: Elsevier/Academic Press, 2013, xxii, 1519 s. ISBN 978-0-12-374626-9.
  • HOLLINGER, Jeffrey O. An introduction to biomaterials. 2nd ed. Boca Raton: CRC Press/Taylor & Francis, c2012, xix, 624 s. The biomedical engineering series. ISBN 978-1-4398-1256-3.
Teaching methods
lectures
Assessment methods
oral exam
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught once in two years.
Information on the per-term frequency of the course: Předmět je vypisován pouze v lichých letech.
The course is taught: in blocks.
Information on the extent and intensity of the course: 3 bloky po 4 hodinách.
The course is also listed under the following terms Spring 2017, Spring 2019, Spring 2021, Spring 2023.
  • Enrolment Statistics (Spring 2025, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2025/Bi6000