Bi7071 Bioanalytics II - Laboratory medicine

Faculty of Science
Spring 2009
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
Teacher(s)
doc. Mgr. Jan Havliš, Dr. (lecturer)
Guaranteed by
doc. Mgr. Jan Havliš, Dr.
Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites
basic knowledge of biochemistry, of analytical, organic and inorganic chemistry are pre-requisited.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 9 fields of study the course is directly associated with, display
Course objectives
main objectives of lecture: introduction into laboratory diagnostics; defining relation between bioanalysis and illness diagnosis; acquainting respective approaches through method selection, analyte determination to results presentation; introduction of basic methodical approaches and common instrumental techniques.
Syllabus
  • 1. introduction, samples - preanalytical phase
  • 2. instrumentation - analysers; organisation, integration and miniaturisation of analyses
  • 3. quality in clinical analysis - check and control
  • 4. analytical methods - selection and optimisation
  • 5. analytical sets; analytical result - its presentation; selected instrumental methods
  • 6. colourness - physical phenomenon and its utilisation in bioanalysis; medical microbiology
  • 7. clinical immunoanalysis
  • 8. clinical aspects of protein analysis
  • 9. clinical aspects of DNA analysis
  • 10. case study - development of a method for clinical diagnostics; role of buffers in bioanalysis
  • 11. selected analytes 1 - inorganic
  • 12. selected analytes 2 - organic and macromolecules
Literature
  • Tietz fundamentals of clinical chemistry. Edited by Carl A. Burtis - Edward R. Ashwood - David E. Bruns - Barbara G. Sawye. 6th ed. St. Louis, Mo.: Saunders/Elsevier, 2008, xx, 952. ISBN 9780721638652. info
  • Clinical laboratory diagnostics : use and assessment of clinical laboratory results. Edited by Lothar Thomas. 1st ed. Frankfurt am Main: TH-Books, 1998, 1527 s. ISBN 3980521540. info
Assessment methods
the lecture is based on ppt presentation and its explication, presentation its-self will be available as a study material (black-and-white printable pdf with high resolution and restricted access rights). it is recommended to attend the lecture, because of the explication, which extends the presentation.
oral examination; students are required to understand and be familiar with the principles and its applications; enumerations, listing of facts and suchs would not be required.
Language of instruction
English
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2010, Spring 2011, spring 2012 - acreditation.
  • Enrolment Statistics (Spring 2009, recent)
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