C3070 Organic Chemistry for Biologists - laboratory course

Faculty of Science
Autumn 2008
Extent and Intensity
0/3/0. 3 credit(s). Type of Completion: z (credit).
Teacher(s)
Ing. Alena Pálková (seminar tutor)
prof. RNDr. Milan Potáček, CSc. (lecturer)
RNDr. Slávka Janků, Ph.D. (seminar tutor)
Ing. Viktor Kolman, Ph.D. (seminar tutor)
Mgr. Zdeněk Moravec, Ph.D. (assistant)
Guaranteed by
prof. RNDr. Milan Potáček, CSc.
Department of Chemistry – Chemistry Section – Faculty of Science
Timetable of Seminar Groups
C3070/01: Thu 11:00–16:50 C10/109, S. Janků
C3070/02: Thu 11:00–16:50 C10/109, S. Janků
C3070/03: Thu 11:00–16:50 C10/109, V. Kolman
Prerequisites
C1620 General and Inorg.Chem.-lab.
C2021, C1080 Successful computer based test is condition for laboratory entrance.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Fundamental laboratory methods of organic chemistry for synthesis (heating, stirring, cooling, introduction of gases, working with decrease of pressure, drying) and separation of organic compounds (filtering, crystallization, distillation, extraction). The methods are trained an the compounds synthesis of important types of organic reactions. The products are characterized by melting point, thin-layer chromathography, refractive index, and infra-red spectroscopy. The aim of the course is to teach students the basic methods of laboratory technique of organic chemistry with the aim to bring them to knowledge to synthesize compounds according with the literature information.
Syllabus
  • 1. Phenole nitration(SEAr mechanism, steam distillation, recrystallization) 2. Ethyl 3-oxobutanoate ethylenacetale(AN mechanism to C=O, azeotropic and vacuum distillation, work with rotary evaporator) 3. Benzoic acid(AN to C=O, work with anhydrous solvents, praparation of Grignard reagent, extraction, sublimation) 4. Anthranilic acid (Hofmannovo odbourávání amide, recrystallization) 5. Ethyl-acetate (esterifikace, distillation) 6. 2-Hydroxy-5-methyl-2'-nitroazobenzene (diazotization and diazonium coupling, recrystallization, TLC)
Literature
  • NOVÁČEK, Eduard and Milan POTÁČEK. Laboratorní technika ke cvičení z metod organické chemie. Edited by Slávka Janků. 1. vyd. Brno: Masarykova univerzita, 1997, 91 s. ISBN 8021015004. info
Assessment methods
Preparation for the ability to enter laboratory before every laboratory course is tested by computer managed tests on methods of laboratory technique, knowledge of reaction mechanism as well as safety regulations connected with the certain synthesis. The course is closed by graded credits.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
General note: Vyučují učitelé katedry organické chemie.
Information on course enrolment limitations: NOW(C3022)
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2009.
  • Enrolment Statistics (Autumn 2008, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2008/C3070