C8435 Heterocyclic compounds

Faculty of Science
Spring 2015
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
prof. RNDr. Milan Potáček, CSc. (lecturer)
Guaranteed by
prof. RNDr. Milan Potáček, CSc.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science
Prerequisites
C2021 Organic Chemistry I && C3022 Organic Chemistry II/1
General knowledge of basic Organic Chemistry
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
At the end of the course the student will be able to identify and name all the basic and fused heterocyclic compounds, evaluate their reactivity and find a pathway to their synthesis.
Syllabus
  • Heterocyclic compounds 2014/2015 PS, 2/0/0 1) Nomenklatura of heterocyclic compounds,Hantzsch - Widman rules, nomenclature of fused heterocycles, numbering of the fused systems. 2) Structure of aromatic heterocycles. 3) Substitution reactions at aromatic heterocycles. 4) Chemistry of organometallic heterocycles. 5) Synthesis of aromatic heterocycles. 6) Typical properties and reactivity of azoles (pyrrole, furane, thiophene). 7) Typical properties, reactivity and synthesis of pyridines, quinolines a isoquinolines I. 8) Typical properties, reactivity and synthesis of pyridines, quinolines a isoquinolines II. 9) Pyrylium and benzopyrylium, pyrones and benzopyrones (reactivity and synthesis) I. 10) Pyrylium and benzopyrylium, pyrones and benzopyrones (reactivity and synthesis) II. 11) Diazines (pyridazine, pyrimidine and pyrazine), reactivity and synthesis). 12) 1,2- a 1,3-azoles – structure and properties. 13) Saturated and partially saturated heterocycles. 14) Special heterocyclic compounds.
Literature
    recommended literature
  • SAINSBURY, M. Heterocyclic chemistry. Cambridge, UK: Royal Society of Chemistry, 2001, vi, 142. ISBN 0854046526. info
    not specified
  • KATRITZKY, Alan R. Handbook of heterocyclic chemistry. 3rd ed. Kidlington: Elsevier, 2010, 1004 s. ISBN 9780080958439. info
  • Heterocycles in life and societyan introduction to heterocyclic chemistry, biochemistry and applications. Edited by A. F. Pozharskiæi - Alan R. Katritzky - A. T. Soldatenkov. 2nd ed. Chichester, West Sussex: Wiley, 2011, xi, 382 p. ISBN 9781119998389. info
Teaching methods
Lectures connected with discussion of synthetic methods.
Assessment methods
oral examination
Language of instruction
Czech
The course is also listed under the following terms Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.
  • Enrolment Statistics (Spring 2015, recent)
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