PřF:C8967 <sup>15</sup>N NMR - Course Information

C8967 ¹⁵N NMR Spectroscopy

Faculty of Science
spring 2018

Extent and Intensity

1/0/0. 1 credit(s) (plus 1 credit for an exam). Type of Completion: k (colloquium).

Teacher(s)

prof. RNDr. Radek Marek, Ph.D. (lecturer)

Guaranteed by

Prerequisites (in Czech)

Target group: advanced undergraduates and Ph.D. students Prerequisites: basic knowledge of high-resolution NMR spectroscopy

Course Enrolment Limitations

The course is offered to students of any study field.

Syllabus (in Czech)

1.-2. Basics of NMR spectroscopy: general considerations, ¹⁴N vs. ¹⁵N, natural abundance, line shape, relaxation, NOE, polarization transfer, ¹H-¹⁵N correlation experiments 3.-4. NMR in solution: ¹⁵N NMR chemical shift, X-¹⁵N coupling constants, magnetic field gradients, optimization of experiments, probeheads 5.-6. Solid-state NMR: ¹⁵N chemical shift tensor (CST), chemical shift anisotropy, principal components of CST, ¹⁵N CP/MAS, ¹H-¹⁵N dipolar couplings, interatomic distances 7.-8. Quantum chemical calculations of ¹⁵N NMR parameters: geometry, chemical shielding, indirect spin-spin couplings 9.-10. Structural problems: regioisomerism, rotational isomerism, tautomerism, protonation, complexation, N-oxidation 11.-14: Applications: Interpretation of high-resolution ¹H-¹⁵N NMR spectra, practical aspects

Language of instruction

English

Further Comments

The course is taught once in two years.
The course is taught: in blocks.

Teacher's information