CH2BP_2P8P Organic Chemistry 1

Faculty of Education
Spring 2004
Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. Jiří Šibor, Ph.D. (lecturer)
Guaranteed by
Mgr. Jiří Šibor, Ph.D.
Department of Physics, Chemistry and Vocational Education – Faculty of Education
Contact Person: Alena Vozdecká
Timetable
Mon 13:45–15:20 učebna 5
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The subject of organic chemistry. Nomenclature of organic chemistry. Principles of organic chemistry. General criteria of chemical reaction. Spectral properties of organic compounds. Alkanes and cycloalkanes. Optical activity and symmetry of molecules. Alkenes. Dienes and polyenes. Isoprenoides. Steroids. Pericyclic reactions. Alkynes. Aromatic compounds.
Syllabus
  • The subject of organic chemistry. Nomenclature of organic chemistry. Name of compounds formation. Chemical bonds and bonding in organic molecules. Hybridization of the carbon atom, bonding energy, bond length, polarity of the chemical bond. Inductive and mesomeric effects, conjugation. Steric effects. General criteria of chemical reaction - reaction kinetics, reaction profiles and mechanism. Activation energy and enthalpy of the reaction. Chemical. Acidity and basicity. Arrhenius, Brønsted and Lewis explanation, acids and bases, pKa and pH. Spectral properties of organic compounds. Electronic spectra. Infrared spectroscopy, Nuclear magmetic resonance, mass spectroscopy. Alkanes and cycloalkanes. Chain isomerie, conformation analysis of alkanes and cycloalkanes. Fused cyclic systems. Newmann projection. cis-trans- Isomerism of cycloalkanes. Radical reactions as typical reactions of this system. Summary of radical reactions. Optical activity and symmetry of molecules. Chiral molecules, conditions of chirality. Methods of space objects presentation. Enantiomers, optical activity, specific rotation and its measurement, optical purity, racemic mixture. Molecules with more than one stereocenter. Cahn, Ingold, Prelog rules. Alkenes, stereochemistry of double bond, cis-trans and E-Z nomenclature. Addition reactions, their summary with attention to the stereochemistry and mechanism. Polymerizations. Dienes and polyenes (cumulated, isolated, conjugated). Reactions of conjugated dienes, conditions and mechanism of 1,2- and 1,4-addition. Isoprenoides (monoterpenes, sesquiterpenes, di-, tri- and tetraterpenes, carotenes). Steroids. Pericyclic reactions - electrocyclic reactions, cycloaddition reactions, the rules of their realization, sigmatropic rearrangements. Alkynes and their structure. Properties of the triple bond, addition reactions (electrophilic and nucleophilic additions), acidity of the hydrogen atoms bound on sp- carbon. Aromatic compounds.The phenomenon of aromaticity and its properties. Nonbenzoid aromates (polycyclic aromates, annulenes, aromatic ions.} Mechanism of aromatic electrophilic substitution. Summary of electrophilic reactions, formation of electrophilic reagents. Effect of substituents on the reactivity and orientation. Hammet equation, sigma and rho constants. Ipso substitution. Nucleophilic substitution on the aromatic ring (SN1, SN2, elimination-addition mechanism). Conditions for addition reactions and reactions of oxidation. Substitution a other reactions on fused aromatic compounds.
Literature
  • MCMURRY, John. Fundamentals of organic chemistry. 4th ed. Pacific Grove: Brooks/Cole publishing company, 1998, xxii, 566,. ISBN 0-534-35245-4. info
  • SOLOMONS, T. W. Graham. Organic chemistry. 6th ed. New York: John Wiley & Sons, 1996, xxvii, 121. ISBN 0471013420. info
  • HRNČIAR, Pavol. Organická chémia. 3., preprac. vyd. Bratislava: Slovenské pedagogické nakladateľstvo, 1990, 708 s. ISBN 8008000287. info
  • ČERVINKA, Otakar. Chemie organických sloučenin. Vyd. 1. Praha: Státní nakladatelství technické literatury, 1987, 1052 s. info
  • ČERVINKA, Otakar, Václav DĚDEK and Miloslav FERLES. Organická chemie. 2., přeprac. vyd. Praha: Státní nakladatelství technické literatury, 1980, 791 s. info
  • ČERVINKA, Otakar. Mechanismy organických reakcí. Vyd. 1. Praha: Státní nakladatelství technické literatury, 1976, 483 s. info
Assessment methods (in Czech)
Typ výuky: přednáška
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is also listed under the following terms Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018.
  • Enrolment Statistics (Spring 2004, recent)
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