RV2MP_2GE Genetics 2

Faculty of Education
Spring 2012
Extent and Intensity
1/0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
Mgr. et Mgr. Lenka Falk, Ph.D. (lecturer)
Guaranteed by
prof. MUDr. Bc. Zuzana Derflerová Brázdová, DrSc.
Department of Health Education – Faculty of Education
Contact Person: Michaela Daňková
Supplier department: Department of Health Education – Faculty of Education
Timetable
Thu 8:50–9:35 učebna 20
Prerequisites (in Czech)
RV2BP_5GE Genetics 1
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
At the end of this course, students should be able to: - understand and to interpret bases of cell biology and molecular biology and genetics - interpret a substance of genetic code – redundance, universality, cause of gene transcription and translation - explain nucleosome structure of chromosome - explein mutations and effect of mutations - describe the cell cycle - explain the use of knowledge about the cell cycle in cancer treatment. pharmacogenetics, organ transplantation - interpret therms: telomere, appoptosis, necrosis, cell death.
Syllabus
  • Expression of genetic information – model tasks. Molecular base of genetic, chromosome and genome mutations. News from molecular genetics: human genes for sports performance, for issue of pathological addictions leading to obesity, etc. Types of cells and tissues. Cell in light and electron microscope. Investigation and drawings of chosen histological sections. Fluorescent microscopy – principle, application. Direct and indirect fluorescence. Immunofluorescence. Visualization of microtubules and actin microfilaments by use of fluorescent microscopy. Demonstration of chromosome aberrations by use of fluorescent methods. Types of communication between a cell and a virus. Cell necrosis, cell apoptosis. Destiny of cells in multicellular (human) organism. Demonstrations of practical application of a video during lessons in primary schools with the aim to solve some chosen simple exercises from cytology.
Literature
  • CHALUPOVÁ-KARLOVSKÁ, Vlastimila. Obecná biologie : evoluce, biologie buňky, genetika s 558 řešenými testovými otázkami. 1. vyd. Olomouc: Nakladatelství Olomouc, 2004, 206 s. ISBN 8071821748. info
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
  • Praktická cvičení z biologie. Edited by Milan Hejtmánek. 4. vyd. Olomouc: Univerzita Palackého, 1999, 204 s. ISBN 8024400146. info
  • ROSYPAL, Stanislav. Úvod do molekulární biologie. Díl druhý, (Makromolekulární biologie eukaryot). 3. inovované vyd. Brno: Stanislav Rosypal, 1999, s. 304-600. ISBN 80-902562-1-X. info
  • Buněčné základy životních dějů. Edited by Václav Kubišta. 1. vyd. Praha: Scientia, 1998, 210 s., il. ISBN 80-7183-109-3. info
  • BERGER, Josef. Biologie :učebnice pro gymnázia a střední odborné školy. Vyd. 1. Havlíčkův Brod: TOBIÁŠ, 1996, 167 s. ISBN 80-85808-42-0. info
  • HAVELKOVÁ, Marie. Pravděpodobnost a její význam v dědičnosti. 3. přeprac. vyd. Brno: Univerzita J.E.Purkyně, 1988, 39 s. info
Teaching methods
The whole course is finished by an oral exam consisting of two parts: a) practical part – a student solves and defends a particular genetic model example which he/she has selected from a topic list of 95 items, b) theoretical part– a student answers and explains two theoretical topics from general genetics which he/she has selected from 40 double topics list.
Assessment methods
The whole course is finished by an oral exam consisting of two parts: a) practical part – a student solves and defends a particular genetic model example which he/she has selected from a topic list of 95 items, b) theoretical part– a student answers and explains two theoretical topics from general genetics which he/she has selected from 40 double topics list.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Spring 2008, Spring 2009, Spring 2010, Spring 2011.
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