Course Information

BVGE061 Genetics

Extent and Intensity

1/0/0. 2 credit(s). Type of Completion: zk (examination).
Taught in person.

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Jan Kučera, Ph.D. (lecturer)
Mgr. Peter Lenárt, Ph.D. (lecturer)
Mgr. Jana Fialová Kučerová, Ph.D. (lecturer)
Mgr. Lucie Štrublová (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine

Timetable

Mon 19. 2. 9:00–11:30 A18/208, Mon 26. 2. 9:00–11:30 A18/208, Mon 4. 3. 9:00–11:30 A18/208, Mon 25. 3. 9:00–11:30 A18/208

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 15.

BVGE061 Genetics

Extent and Intensity

1/0/0. 2 credit(s). Type of Completion: zk (examination).
Taught in person.

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Jan Kučera, Ph.D. (lecturer)
Mgr. Jana Fialová Kučerová, Ph.D. (lecturer)
Mgr. Lucie Štrublová (lecturer)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine

Timetable

Mon 20. 3. 9:00–11:30 A19/118, Mon 27. 3. 9:00–11:30 A19/118, Mon 3. 4. 9:00–11:30 A19/118, Mon 17. 4. 9:00–11:30 A19/118

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 15.

BVGE061 Genetics

Extent and Intensity

1/0/0. 2 credit(s). Type of Completion: zk (examination).
Taught in person.

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Jan Kučera, Ph.D. (lecturer)
Mgr. Peter Lenárt, Ph.D. (lecturer)
Mgr. Jana Fialová Kučerová, Ph.D. (lecturer)
Mgr. Lucie Štrublová (lecturer)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine

Timetable

Mon 14. 2. 9:00–11:30 C15/333, Mon 21. 2. 9:00–11:30 C15/333, Mon 28. 2. 9:00–11:30 C15/333, Mon 7. 3. 9:00–11:30 C15/333, Mon 14. 3. 9:00–11:30 C15/333

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 15.

BVGE061 Genetics

Extent and Intensity

1/0/0. 2 credit(s). Type of Completion: zk (examination).
Taught online.

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Markéta Grulichová, Ph.D. (lecturer)
Mgr. Pavel Hruška, Ph.D. (lecturer)
Mgr. Jan Kučera, Ph.D. (lecturer)
Mgr. Peter Lenárt, Ph.D. (lecturer)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine

Timetable

Mon 1. 3. 9:00–11:30 C15/333, Mon 8. 3. 9:00–11:30 C15/333, Mon 15. 3. 9:00–11:30 C15/333, Mon 22. 3. 9:00–11:30 C15/333, Mon 29. 3. 9:00–11:30 C15/333

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 15.

BVGE061 Genetics

Extent and Intensity

1/0/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Markéta Grulichová, Ph.D. (lecturer)
Mgr. Pavel Hruška, Ph.D. (lecturer)
Mgr. Jan Kučera, Ph.D. (lecturer)
Mgr. Peter Lenárt, Ph.D. (lecturer)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine

Timetable

Mon 17. 2. 9:00–11:30 B11/327, Mon 24. 2. 9:00–11:30 B11/327, Mon 2. 3. 9:00–11:30 B11/327, Mon 9. 3. 9:00–11:30 B11/327, Mon 16. 3. 9:00–11:30 B11/327

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 15.

BVGE061 Genetics

Extent and Intensity

1/0/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Markéta Grulichová, Ph.D. (lecturer)
Mgr. Pavel Hruška, Ph.D. (lecturer)
Mgr. Jan Kučera, Ph.D. (lecturer)
Mgr. Peter Lenárt, Ph.D. (lecturer)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Public Health – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Public Health – Theoretical Departments – Faculty of Medicine

Timetable

Mon 18. 2. 9:00–11:30 C15/333, Mon 25. 2. 9:00–11:30 C15/333, Mon 4. 3. 9:00–11:30 C15/333, Mon 11. 3. 9:00–11:30 C15/333, Mon 18. 3. 9:00–11:30 C15/333

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 15.

BVGE061 Genetics

Extent and Intensity

1/0/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Pavel Hruška, Ph.D. (lecturer)
Mgr. Markéta Grulichová, Ph.D. (lecturer)
Mgr. Jan Kučera, Ph.D. (lecturer)
Mgr. Peter Lenárt, Ph.D. (lecturer)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Public Health – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Public Health – Theoretical Departments – Faculty of Medicine

Timetable

Mon 19. 2. to Fri 23. 3. Mon 8:30–11:00 B09/324

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Markéta Grulichová, Ph.D. (lecturer)
Mgr. Martin Hořák, Ph.D. (lecturer)
Mgr. Pavel Hruška (lecturer)
Mgr. Jan Kučera, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Public Health – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Public Health – Theoretical Departments – Faculty of Medicine

Timetable

Mon 20. 2. to Fri 24. 3. Mon 8:30–11:00 B09/324

Prerequisites

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture
Biology, Pathological physiology, Nutrition in prevention and health promotion

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After finishing the course, the student will be able to: 1) explain the basics of transmission of genetic information in various organisms including humans 2) explain the basic mechanism of machinery of gene expression 3) explain the relationship between gene expression and nutrition and explain involvement of gene expression in nutritionally-driven diseases 4) give basic examples of gene and chromosomal disorders in humans 5) give basic examples of genetic diseases driven by nutrition and explain the therapeutic strategy in these diseases 6) explain the concept of personalised nutrition including critical evaluation

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

required literature
• Genetika ve výživě - skripta pro nutriční terapeuty, Julie Bienertová-Vašků a kol. 2014

not specified
• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Zbyněk Šplíchal, Ph.D. (lecturer)
Mgr. Jolana Lipková, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Public Health – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Public Health – Theoretical Departments – Faculty of Medicine

Timetable

Mon 22. 2. to Fri 25. 3. Mon 9:10–11:40 B11/327

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
Mgr. Zbyněk Šplíchal, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Public Health – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Public Health – Theoretical Departments – Faculty of Medicine

Timetable

Mon 16. 2. to Tue 17. 3. Mon 9:10–11:40 B11/327

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Preventive Medicine – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Preventive Medicine – Theoretical Departments – Faculty of Medicine

Timetable

Mon 17. 2. to Fri 21. 3. Mon 9:10–11:40 B11/327

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine

Timetable

Mon 18. 2. to Sun 24. 3. Mon 9:30–12:00 B11/234

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

Study Materials
The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine

Timetable

Mon 20. 2. to Fri 23. 3. Fri 8:00–10:30 B11/234

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová

Timetable

Mon 21. 2. to Sat 26. 3. Fri 8:00–10:30 B11/234

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MVDr. Halina Matějová (assistant)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová

Timetable

Fri 12:30–15:00 N02113a

Prerequisites (in Czech)

BKBI011 Biology && BVPF0422p Pathophysiol II - lect && BVVP0533p Nutrition in health promotion and public health III - lecture

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)

Guaranteed by

prof. MUDr. Julie Dobrovolná, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: MVDr. Halina Matějová

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Assessment methods

lecture, semester paper, examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in autumn 2023

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in autumn 2022

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in autumn 2021

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in autumn 2020

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in autumn 2019

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)
• Dietitian (programme LF, B-NUT)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in autumn 2018

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in Autumn 2017

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Learning outcomes

After completion of the course, the students will be able to: 1) explain briefly the basics of mendelian as well as non-mendelian inheritance 2) discuss the basic monogenous diseases that can be modified by diet 3) discuss the basic multigenous diseases that can be modified by diet 4) discuss the concept of the personalized medicine from the perspective of the genetic background of an individual 5) explain the main relationships between gene expression and diet including examples 6) explain the basics of nutrigenetics and nutrigenomics

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• Nutrition and genomics : issues of ethics, law, regulation, and communication. Edited by David Castle - Nola M. Ries. Boston: Elsevier/Academic Press, 2009, xvi, 293. ISBN 9780123741257. info
• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

oral examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in Autumn 2016

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in Autumn 2015

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in Autumn 2013

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in Autumn 2012

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Guaranteed by

Supplier department: Faculty of Medicine

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in Autumn 2011

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in Autumn 2010

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

BVGE061 Genetics

The course is not taught in Autumn 2009

Extent and Intensity

1/0. 2 credit(s). Type of Completion: zk (examination).

Teacher(s)

MVDr. Halina Matějová (assistant)

Course Enrolment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

fields of study / plans the course is directly associated with

• Nutritive therapist (programme LF, B-SZ)

Course objectives

The aim of this subject is to provide the students with the theoretical background they could benefit from in frame of forthcoming trend of construction of individual dietary programmes intended for different subsets of patients, on the grounds of determinantion of their genetic traits. The students will be introduced to the basic concepts of clinical genetics that relate to the nutritional determinants, as well as to the most frequent diseases, the therapy of which requires individualized nutritional practice.

Syllabus

• Human genome and its structure, reaction to environmental factors. Mitochondrial and nuclear heredity. Gene and non-gene determination of biological characteristics from the nutritional perspective. Mutation types (exon, intron, promoter mutations, point mutations and their effects, insertion-deletion mutations, frameshift mutations). Monogenous and polygenous diseases. Relation of the multigene disease to the environment with respect to the qualitative and quantitative aspects of individual nutrition. Civilization diseases as a special sort of multigene disease. Genetics of obesity, stratification of patients based on conceivable genetic risk. Importance of DNA diagnostics in the practice of a dietitian. Nutritional counselling from the genetics perspective. Nutrigenomics.

Literature

• LUCOCK, Mark. Molecular nutrition and genomics : nutrition and the ascent of humankind. 1st ed. Hoboken: Wiley-Liss, 2007, xii, 140. ISBN 9780470081594. info
• NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
• HATINA, Jiří and Brian D. SYKES. Lékařská genetika : problémy a přístupy. Vyd. 1. Praha: Academia, 1999, 296 s. ISBN 8020007008. info

Teaching methods

lecture, semestral assay

Assessment methods

examination

Language of instruction

Czech

Further Comments

The course is taught annually.
The course is taught: every week.

• Enrolment Statistics (recent)