VLBC0422s Biochemistry II - seminar

Faculty of Medicine
spring 2024
Extent and Intensity
0/3/0. 3 credit(s). Type of Completion: z (credit).
Taught in person.
Teacher(s)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
Mgr. Jana Gregorová, Ph.D. (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
Mgr. Jindra Smutná, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
doc. Mgr. Zdenka Fohlerová, Ph.D. (assistant)
Mgr. David Galuška (assistant)
Mgr. Patrícia Kittová (assistant)
doc. PharmDr. Jiří Kos, Ph.D. (assistant)
PharmDr. Kristýna Šebrlová, Ph.D. (assistant)
MUDr. Mgr. Pavel Šmak (assistant)
Mgr. Jan Víteček, Ph.D. (assistant)
Guaranteed by
doc. RNDr. Josef Tomandl, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: RNDr. Hana Paulová, CSc.
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
VLBC0422s/01: Tue 13:30–16:20 A16/213, E. Táborská
VLBC0422s/02: Tue 13:30–16:20 A16/213, E. Táborská
VLBC0422s/03: Mon 8:00–10:50 A16/215, J. Slanina
VLBC0422s/04: Mon 8:00–10:50 A16/215, J. Slanina
VLBC0422s/05: Thu 22. 2. to Thu 9. 5. Thu 13:30–16:20 A16/215, Thu 23. 5. to Thu 30. 5. Thu 13:30–16:20 A16/215, J. Dostál
VLBC0422s/06: Thu 22. 2. to Thu 9. 5. Thu 13:30–16:20 A16/215, Thu 23. 5. to Thu 30. 5. Thu 13:30–16:20 A16/215, J. Dostál
VLBC0422s/07: Wed 8:00–10:50 A16/215, E. Táborská
VLBC0422s/08: Wed 8:00–10:50 A16/215, E. Táborská
VLBC0422s/09: Wed 8:00–10:50 A16/213, J. Dostál
VLBC0422s/10: Wed 8:00–10:50 A16/213, J. Dostál
VLBC0422s/11: Fri 8:00–10:50 A16/215, M. Králíková
VLBC0422s/12: Fri 8:00–10:50 A16/215, M. Králíková
VLBC0422s/13: Fri 8:00–10:50 A16/213, H. Paulová
VLBC0422s/14: Fri 8:00–10:50 A16/213, H. Paulová
VLBC0422s/15: Mon 14:00–16:50 A16/213, M. Tomandlová
VLBC0422s/16: Mon 14:00–16:50 A16/213, M. Tomandlová
VLBC0422s/17: Mon 11:00–13:50 A16/215, J. Gregorová
VLBC0422s/18: Mon 11:00–13:50 A16/215, J. Gregorová
VLBC0422s/19: Mon 14:00–16:50 A16/215, H. Paulová, J. Smutná
VLBC0422s/20: Mon 14:00–16:50 A16/215, H. Paulová, J. Smutná
Prerequisites (in Czech)
VLBC0321s Biochemistry I - seminar && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Seminars are complementary to Biochemistry II - lecture. The aim of the course is to practise (i) the basic principles of intermediary metabolism and its regulation in various states of the organism at all levels, (ii) the characteristic features of metabolism of individual organs and tissues, (iii) the principles of maintaining homeostasis of the organism, including acid-base balance.
Learning outcomes
The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
Syllabus
  • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry. Analysers, POCT.
  • Blood glucose. Protein metabolism. Proteins in nutrition. Transport forms of ammonia.
  • Lipoproteins and their metabolism. Cholesterol transport and balance.
  • Relationships between major metabolic pathways of essential nutrients in various states. Malnutrition. Obesity. Metabolic syndrome. Metabolism during stress.
  • Liver functions, role in nutrient metabolism. Heme catabolism, hyperbilirubinemia. Role of liver in metabolism of hormones and vitamins. Metabolism of Fe.
  • Biotransformation of xenobiotics. Metabolism of ethanol.
  • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volemia.
  • Acid-base balance, parameters, regulation, disorders. Buffer bases. Transport of O2 a CO2.
  • Major functions of kidneys. Glomerular filtration. Tubular resorption and secretion.
  • Neurotransmitters and hormone receptors. The most common signal pathways.
  • Steroid and thyroid hormones.
  • Biochemistry of muscle work. Effect of NO. Energetics of muscle work.
  • Metabolism of Ca, Mg, P, F, I.
  • Extracellular matrix. Metabolism of connective tissue and skin, bone biomarkers.
Literature
    required literature
  • Studijní podklady a materiály k předmětu dostupné v IS MUNI.
  • MURRAY, Robert K., David A. BENDER, Kathleen M. BOTHAM, Peter J. KENNELLY, Victor W. RODWELL and P. Anthony WEIL. Harperova ilustrovaná biochemie. Translated by Bohuslav Matouš. Páté české vydání, prv. Praha: Galén, 2012, xii, 730. ISBN 9788072629077. info
    recommended literature
  • KOOLMAN, Jan and Klaus-Heinrich RÖHM. Barevný atlas biochemie. Translated by Vladimír Benda - Martin Vejražka - Jiří Jonák. 1. české vydání. Praha: Grada, 2012, xiv, 498. ISBN 9788024729770. info
  • Doporučovaná literatura z lékařské fyziologie v předmětu VLFY0422p
Teaching methods
Seminary course. Class discussions on assigned topics.
Assessment methods
Credit. Conditions for giving the course-unit credit:
1) completion of all seminars and 2) completion of in-term tests.
Failure to meet the requirements of in-term tests requires a resit test, which may be repeated only once. All absences must be made up before a resit test.
Detailed conditions are published in Study materials posted under the course/Interactive Syllabus.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
General note: Úspěšné ukončení předmětu je podmínkou přístupu ke zkoušce v předmětu VLBC0422p.
Information on the extent and intensity of the course: 45.
Teacher's information
https://is.muni.cz/auth/el/1411/jaro2024/VLBC0422s/
Information to seminars, the conditions for giving the course-unit credit and the syllabus are available in the IS MUNI in the Course-related instructions.
Consultations are possible after a personal arrangement with the teacher.
The course is also listed under the following terms Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023.

VLBC0422s Biochemistry II - seminar

Faculty of Medicine
spring 2023
Extent and Intensity
0/3/0. 3 credit(s). Type of Completion: z (credit).
Taught in person.
Teacher(s)
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
Mgr. Jana Gregorová, Ph.D. (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
Mgr. Jindra Smutná, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
Mgr. David Galuška (assistant)
Mgr. Patrícia Kittová (assistant)
doc. PharmDr. Jiří Kos, Ph.D. (assistant)
PharmDr. Kristýna Šebrlová, Ph.D. (assistant)
Bc. Ivana Ševčíková (assistant)
MUDr. Mgr. Pavel Šmak (assistant)
Mgr. Jan Víteček, Ph.D. (assistant)
Guaranteed by
doc. RNDr. Josef Tomandl, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: RNDr. Hana Paulová, CSc.
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Timetable of Seminar Groups
VLBC0422s/01: Mon 8:00–10:30 A16/215, J. Slanina
VLBC0422s/02: Mon 8:00–10:30 A16/215, J. Slanina
VLBC0422s/03: Mon 13. 2. to Thu 4. 5. Thu 15:00–17:30 A16/213; and Thu 18. 5. 15:00–17:30 A16/213, Thu 25. 5. 15:00–17:30 A16/213, H. Paulová
VLBC0422s/04: Mon 13. 2. to Thu 4. 5. Thu 15:00–17:30 A16/213; and Thu 18. 5. 15:00–17:30 A16/213, Thu 25. 5. 15:00–17:30 A16/213, H. Paulová
VLBC0422s/05: Mon 11:00–13:30 A16/213, M. Králíková
VLBC0422s/06: Mon 11:00–13:30 A16/213, M. Králíková
VLBC0422s/07: Mon 13. 2. to Thu 4. 5. Thu 8:00–10:30 A16/213; and Thu 18. 5. 8:00–10:30 A16/213, Thu 25. 5. 8:00–10:30 A16/213, J. Dostál
VLBC0422s/08: Mon 13. 2. to Thu 4. 5. Thu 8:00–10:30 A16/213; and Thu 18. 5. 8:00–10:30 A16/213, Thu 25. 5. 8:00–10:30 A16/213, J. Dostál
VLBC0422s/09: Mon 11:00–13:30 A16/215, M. Tomandlová
VLBC0422s/10: Mon 11:00–13:30 A16/215, M. Tomandlová
VLBC0422s/11: Mon 14:00–16:30 A16/215, J. Dostál
VLBC0422s/12: Mon 14:00–16:30 A16/215, J. Dostál
VLBC0422s/13: Mon 14:00–16:30 A16/213, H. Paulová, J. Slanina
VLBC0422s/14: Mon 14:00–16:30 A16/213, H. Paulová, J. Slanina
VLBC0422s/15: Fri 8:00–10:30 A16/215, J. Smutná, E. Táborská
VLBC0422s/16: Fri 8:00–10:30 A16/215, J. Smutná, E. Táborská
VLBC0422s/17: Tue 14:00–16:30 A16/213, E. Táborská
VLBC0422s/18: Tue 14:00–16:30 A16/213, E. Táborská
VLBC0422s/19: Tue 14:00–16:30 A16/215, O. Peš
VLBC0422s/20: Tue 14:00–16:30 A16/215, O. Peš
Prerequisites (in Czech)
VLBC0321s Biochemistry I - seminar && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Seminars are complementary to Biochemistry II - lecture. The aim of the course is to practise (i) the basic principles of intermediary metabolism and its regulation in various states of the organism at all levels, (ii) the characteristic features of metabolism of individual organs and tissues, (iii) the principles of maintaining homeostasis of the organism, including acid-base balance.
Learning outcomes
The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
Syllabus
  • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry. Analysers, POCT.
  • Blood glucose. Protein metabolism. Proteins in nutrition. Transport forms of ammonia.
  • Lipoproteins and their metabolism. Cholesterol transport and balance.
  • Relationships between major metabolic pathways of essential nutrients in various states. Malnutrition. Obesity. Metabolic syndrome. Metabolism during stress.
  • Liver functions, role in nutrient metabolism. Heme catabolism, hyperbilirubinemia. Role of liver in metabolism of hormones and vitamins. Metabolism of Fe.
  • Biotransformation of xenobiotics. Metabolism of ethanol.
  • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volemia.
  • Acid-base balance, parameters, regulation, disorders. Buffer bases. Transport of O2 a CO2.
  • Major functions of kidneys. Glomerular filtration. Tubular resorption and secretion.
  • Neurotransmitters and hormone receptors. The most common signal pathways.
  • Steroid and thyroid hormones.
  • Biochemistry of muscle work. Effect of NO. Energetics of muscle work.
  • Metabolism of Ca, Mg, P, F, I.
  • Extracellular matrix. Metabolism of connective tissue and skin, bone biomarkers.
Literature
    required literature
  • Studijní podklady a materiály k předmětu dostupné v IS MUNI.
  • MURRAY, Robert K., David A. BENDER, Kathleen M. BOTHAM, Peter J. KENNELLY, Victor W. RODWELL and P. Anthony WEIL. Harperova ilustrovaná biochemie. Translated by Bohuslav Matouš. Páté české vydání, prv. Praha: Galén, 2012, xii, 730. ISBN 9788072629077. info
    recommended literature
  • KOOLMAN, Jan and Klaus-Heinrich RÖHM. Barevný atlas biochemie. Translated by Vladimír Benda - Martin Vejražka - Jiří Jonák. 1. české vydání. Praha: Grada, 2012, xiv, 498. ISBN 9788024729770. info
  • Doporučovaná literatura z lékařské fyziologie v předmětu VLFY0422p
Teaching methods
Seminary course. Class discussions on assigned topics.
Assessment methods
Course-unit credit.
Conditions for giving the course-unit credit (all conditions should be met):
  • completion of all lessons,
  • minimal success rate of 70 % from all revision tests or minimal success rate of 50 % from the credit test. The resit credit test can be taken only once.
    The detailed conditions are posted in IS MUNI (Study materials – Course-related instructions).
    • Language of instruction
    Czech
    Further comments (probably available only in Czech)
    The course is taught annually.
    General note: Úspěšné ukončení předmětu je podmínkou přístupu ke zkoušce v předmětu VLBC0422p.
    Information on the extent and intensity of the course: 45.
    Teacher's information
    https://is.muni.cz/auth/el/1411/jaro2024/VLBC0422s/
    Information to seminars, the conditions for giving the course-unit credit and the syllabus are available in the IS MUNI in the Course-related instructions. The syllabus is also posted on the notice board of the Department of Biochemistry.
    Consultations are possible after a personal arrangement with the teacher.
    The course is also listed under the following terms Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2024.

    VLBC0422s Biochemistry II - seminar

    Faculty of Medicine
    spring 2022
    Extent and Intensity
    0/3/0. 3 credit(s). Type of Completion: z (credit).
    Taught in person.
    Teacher(s)
    doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
    Mgr. Jana Gregorová, Ph.D. (seminar tutor)
    MUDr. Michaela Králíková, Ph.D. (seminar tutor)
    RNDr. Hana Paulová, CSc. (seminar tutor)
    doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
    Mgr. Jiří Slanina, Ph.D. (seminar tutor)
    Mgr. Jindra Smutná, Ph.D. (seminar tutor)
    prof. RNDr. Eva Táborská, CSc. (seminar tutor)
    doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
    Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
    Mgr. David Galuška (assistant)
    doc. PharmDr. Jiří Kos, Ph.D. (assistant)
    Bc. Ivana Ševčíková (assistant)
    MUDr. Mgr. Pavel Šmak (assistant)
    Guaranteed by
    doc. RNDr. Josef Tomandl, Ph.D.
    Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Contact Person: prof. RNDr. Eva Táborská, CSc.
    Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Timetable of Seminar Groups
    VLBC0422s/01: Thu 15:00–17:30 A16/213, M. Králíková
    VLBC0422s/02: Thu 15:00–17:30 A16/213, M. Králíková
    VLBC0422s/03: Thu 15:00–17:30 A16/215, J. Dostál
    VLBC0422s/04: Thu 15:00–17:30 A16/215, J. Dostál
    VLBC0422s/05: Mon 8:00–10:30 A16/213, J. Gregorová
    VLBC0422s/06: Mon 8:00–10:30 A16/213, J. Gregorová
    VLBC0422s/07: Mon 8:00–10:30 A16/215, E. Táborská
    VLBC0422s/08: Mon 8:00–10:30 A16/215, E. Táborská
    VLBC0422s/09: Wed 16:00–18:30 A16/215, H. Paulová, J. Slanina
    VLBC0422s/10: Wed 16:00–18:30 A16/215, H. Paulová, J. Slanina
    VLBC0422s/11: Mon 11:00–13:30 A16/215, M. Králíková
    VLBC0422s/12: Mon 11:00–13:30 A16/215, M. Králíková
    VLBC0422s/13: Mon 14:00–16:30 A16/213, E. Táborská
    VLBC0422s/14: Mon 14:00–16:30 A16/213, E. Táborská
    VLBC0422s/15: Fri 8:00–10:30 A16/213, H. Paulová
    VLBC0422s/16: Fri 8:00–10:30 A16/213, H. Paulová
    VLBC0422s/17: Tue 14:00–16:30 A16/215, M. Tomandlová
    VLBC0422s/18: Tue 14:00–16:30 A16/215, M. Tomandlová
    VLBC0422s/19: Fri 8:00–10:30 A16/215, J. Dostál, M. Tomandlová
    VLBC0422s/20: Fri 8:00–10:30 A16/215, J. Dostál, M. Tomandlová
    Prerequisites (in Czech)
    VLBC0321s Biochemistry I - seminar && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
    Course Enrolment Limitations
    The course is only offered to the students of the study fields the course is directly associated with.
    fields of study / plans the course is directly associated with
    Course objectives
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Learning outcomes
    The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
    Syllabus
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods).
    • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion.
    • Blood glucose (sources, consumption, regulation). Diabetes mellitus.
    • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation.
    • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity.
    • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia.
    • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol.
    • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders.
    • Major functions of the kidney. Glomerular filtration.
    • Tubular resorption and secretion.
    • Neurotransmitters and hormone receptors. The most common signal pathways.
    • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism.
    • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin.
    • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literature
      required literature
    • Podklady k seminářům dostupné v IS MUNI.
    • MURRAY, Robert K., David A. BENDER, Kathleen M. BOTHAM, Peter J. KENNELLY, Victor W. RODWELL and P. Anthony WEIL. Harperova ilustrovaná biochemie. Translated by Bohuslav Matouš. Páté české vydání, prv. Praha: Galén, 2012, xii, 730. ISBN 9788072629077. info
      recommended literature
    • KOOLMAN, Jan and Klaus-Heinrich RÖHM. Barevný atlas biochemie. Translated by Vladimír Benda - Martin Vejražka - Jiří Jonák. 1. české vydání. Praha: Grada, 2012, xiv, 498. ISBN 9788024729770. info
    Teaching methods
    Seminary course. Class discussions on assigned topics.
    Assessment methods
    Course-unit credit.
    Conditions for giving the course-unit credit (all conditions should be met):
  • completion of all lessons,
  • minimal success rate of 70 % from all revision tests or minimal success rate of 50 % from the credit test. The resit credit test can be taken only once.
    The detailed conditions are posted in IS MUNI (Study materials – Course-related instructions).
    • Language of instruction
    Czech
    Further comments (probably available only in Czech)
    The course is taught annually.
    General note: Úspěšné ukončení předmětu je podmínkou přístupu ke zkoušce v předmětu VLBC0422p.
    Information on the extent and intensity of the course: 45.
    Teacher's information
    https://is.muni.cz/auth/el/1411/jaro2022/VLBC0422s/
    Information to seminars, the conditions for giving the course-unit credit and the syllabus are available in the IS MUNI in the Course-related instructions. The syllabus is also posted on the notice board of the Department of Biochemistry.
    Consultations are possible after a personal arrangement with the teacher.
    The course is also listed under the following terms Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2023, spring 2024.

    VLBC0422s Biochemistry I - seminar

    Faculty of Medicine
    spring 2021
    Extent and Intensity
    0/3/0. 2 credit(s). Type of Completion: z (credit).
    Taught online.
    Teacher(s)
    doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
    Mgr. Jana Gregorová, Ph.D. (seminar tutor)
    MUDr. Michaela Králíková, Ph.D. (seminar tutor)
    RNDr. Hana Paulová, CSc. (seminar tutor)
    doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
    Mgr. Jiří Slanina, Ph.D. (seminar tutor)
    prof. RNDr. Eva Táborská, CSc. (seminar tutor)
    doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
    Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
    Mgr. Martina Drabinová (assistant)
    doc. Mgr. Zdenka Fohlerová, Ph.D. (assistant)
    Mgr. David Galuška (assistant)
    MUDr. Lenka Gescheidtová, Ph.D. (assistant)
    MUDr. Miroslava Hlaváčová, Ph.D. (assistant)
    MUDr. RNDr. Michal Řiháček, Ph.D., EuSpLM (assistant)
    Mgr. Jindra Smutná, Ph.D. (assistant)
    Mgr. Jan Víteček, Ph.D. (assistant)
    Guaranteed by
    prof. RNDr. Eva Táborská, CSc.
    Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Timetable of Seminar Groups
    VLBC0422s/01: Mon 11:00–13:30 A16/213, J. Dostál
    VLBC0422s/02: Mon 11:00–13:30 A16/213, J. Dostál
    VLBC0422s/03: Tue 14:00–16:30 A16/215, M. Králíková
    VLBC0422s/04: Tue 14:00–16:30 A16/215, M. Králíková
    VLBC0422s/05: Mon 8:00–10:30 A16/213, J. Slanina
    VLBC0422s/06: Mon 8:00–10:30 A16/213, J. Slanina
    VLBC0422s/07: Wed 11:00–13:30 A16/215, H. Paulová
    VLBC0422s/08: Wed 11:00–13:30 A16/215, H. Paulová
    VLBC0422s/09: Wed 11:00–13:30 A16/213, H. Paulová
    VLBC0422s/10: Wed 11:00–13:30 A16/213, H. Paulová
    VLBC0422s/11: Mon 14:00–16:30 A16/215, E. Táborská
    VLBC0422s/12: Mon 14:00–16:30 A16/215, E. Táborská
    VLBC0422s/13: Mon 11:00–13:30 A16/215, J. Dostál
    VLBC0422s/14: Mon 11:00–13:30 A16/215, J. Dostál
    VLBC0422s/15: Tue 13:00–15:30 A16/213, M. Tomandlová
    VLBC0422s/16: Tue 13:00–15:30 A16/213, M. Tomandlová
    VLBC0422s/17: Mon 14:00–16:30 A16/213, E. Táborská
    VLBC0422s/18: Mon 14:00–16:30 A16/213, E. Táborská
    Prerequisites (in Czech)
    ( VLBI0222p Biology II-lect. || VSBI0222p Biology II-lect. ) && VLBF011p Biophysics-lect. && VLBC0321s Biochemistry I sem && VLBC0321c Biochemistry I && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
    Course Enrolment Limitations
    The course is only offered to the students of the study fields the course is directly associated with.
    fields of study / plans the course is directly associated with
    Course objectives
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Learning outcomes
    The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
    Syllabus
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods).
    • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion.
    • Blood glucose (sources, consumption, regulation). Diabetes mellitus.
    • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation.
    • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity.
    • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia.
    • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol.
    • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders.
    • Major functions of the kidney. Glomerular filtration.
    • Tubular resorption and secretion.
    • Neurotransmitters and hormone receptors. The most common signal pathways.
    • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism.
    • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin.
    • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literature
      required literature
    • Podklady k seminářům v IS.
    Teaching methods
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended text. Complementary materials are available in section Study materials.
    Assessment methods
    Conditions of giving the credits • Submission of all completed protocols with answers to the Homework Vaults in relevant dates. • Required attendance in seminars. • All absences must be made up according to teacher instructions. • Obtaining 52 points or more from continuous revision tests or • Obtaining 14 points from the credit test
    Language of instruction
    Czech
    Further comments (probably available only in Czech)
    The course is taught annually.
    Information on the extent and intensity of the course: 45.
    The course is also listed under the following terms Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2022, spring 2023, spring 2024.

    VLBC0422s Biochemistry I - seminar

    Faculty of Medicine
    spring 2020
    Extent and Intensity
    0/3/0. 2 credit(s). Type of Completion: z (credit).
    Teacher(s)
    doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
    Mgr. Jana Gregorová, Ph.D. (seminar tutor)
    MUDr. Michaela Králíková, Ph.D. (seminar tutor)
    RNDr. Hana Paulová, CSc. (seminar tutor)
    doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
    Mgr. Jiří Slanina, Ph.D. (seminar tutor)
    prof. RNDr. Eva Táborská, CSc. (seminar tutor)
    doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
    Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
    Mgr. Martina Drabinová (assistant)
    MUDr. Lenka Gescheidtová, Ph.D. (assistant)
    MUDr. Miroslava Hlaváčová, Ph.D. (assistant)
    PharmDr. Katarína Kostolanská (assistant)
    RNDr. Marianna Romžová, Ph.D. (assistant)
    MUDr. RNDr. Michal Řiháček, Ph.D., EuSpLM (assistant)
    Mgr. Jindra Smutná, Ph.D. (assistant)
    Guaranteed by
    prof. RNDr. Eva Táborská, CSc.
    Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Contact Person: Monika Šudáková
    Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Timetable of Seminar Groups
    VLBC0422s/01: Mon 11:00–13:30 A16/213, J. Gregorová
    VLBC0422s/02: Mon 11:00–13:30 A16/213, J. Gregorová
    VLBC0422s/03: Tue 13:00–15:30 A16/215, M. Tomandlová
    VLBC0422s/04: Tue 13:00–15:30 A16/215, M. Tomandlová
    VLBC0422s/05: Mon 8:00–10:30 A16/213, J. Slanina
    VLBC0422s/06: Mon 8:00–10:30 A16/213, J. Slanina
    VLBC0422s/07: Thu 12:00–14:30 A16/215, M. Králíková
    VLBC0422s/08: Thu 12:00–14:30 A16/215, M. Králíková
    VLBC0422s/09: Thu 15:00–17:30 A16/215, E. Táborská, J. Tomandl
    VLBC0422s/10: Thu 15:00–17:30 A16/215, E. Táborská, J. Tomandl
    VLBC0422s/11: Thu 13:00–15:30 A16/213, J. Dostál
    VLBC0422s/12: Thu 13:00–15:30 A16/213, J. Dostál
    VLBC0422s/13: Tue 16:00–18:30 A16/213, E. Táborská
    VLBC0422s/14: Tue 16:00–18:30 A16/213, E. Táborská
    VLBC0422s/15: Tue 16:00–18:30 A16/215, H. Paulová
    VLBC0422s/16: Tue 16:00–18:30 A16/215, H. Paulová
    Prerequisites (in Czech)
    ( VLBI0222p Biology II-lect. || VSBI0222p Biology II-lect. ) && VLBF011p Biophysics-lect. && VLBC0321s Biochemistry I sem && VLBC0321c Biochemistry I && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
    Course Enrolment Limitations
    The course is only offered to the students of the study fields the course is directly associated with.
    fields of study / plans the course is directly associated with
    Course objectives
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Learning outcomes
    The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
    Syllabus
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods).
    • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion.
    • Blood glucose (sources, consumption, regulation). Diabetes mellitus.
    • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation.
    • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity.
    • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia.
    • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol.
    • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders.
    • Major functions of the kidney. Glomerular filtration.
    • Tubular resorption and secretion.
    • Neurotransmitters and hormone receptors. The most common signal pathways.
    • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism.
    • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin.
    • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literature
      required literature
    • Podklady k seminářům v IS.
    Teaching methods
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Assessment methods
    course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.
    Language of instruction
    Czech
    Further comments (probably available only in Czech)
    The course is taught annually.
    Information on the extent and intensity of the course: 45.
    The course is also listed under the following terms Spring 2017, Spring 2018, spring 2019, spring 2021, spring 2022, spring 2023, spring 2024.

    VLBC0422s Biochemistry I - seminar

    Faculty of Medicine
    spring 2019
    Extent and Intensity
    0/3/0. 2 credit(s). Type of Completion: z (credit).
    Teacher(s)
    Ing. Martina Čarnecká, Ph.D. (seminar tutor)
    doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
    Mgr. Jana Gregorová, Ph.D. (seminar tutor)
    MUDr. Michaela Králíková, Ph.D. (seminar tutor)
    RNDr. Hana Paulová, CSc. (seminar tutor)
    doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
    Mgr. Jiří Slanina, Ph.D. (seminar tutor)
    prof. RNDr. Eva Táborská, CSc. (seminar tutor)
    doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
    Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
    Mgr. Martina Drabinová (assistant)
    MUDr. Lenka Gescheidtová, Ph.D. (assistant)
    MUDr. Miroslava Hlaváčová, Ph.D. (assistant)
    PharmDr. Katarína Kostolanská (assistant)
    Lenka Nerudová (assistant)
    Mgr. Lucie Novotná (assistant)
    Mgr. Anna Pleskačová, Ph.D. (assistant)
    MUDr. RNDr. Michal Řiháček, Ph.D., EuSpLM (assistant)
    Mgr. Roman Sándor, Ph.D. (assistant)
    Mgr. Jindra Smutná, Ph.D. (assistant)
    Guaranteed by
    prof. RNDr. Eva Táborská, CSc.
    Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Timetable of Seminar Groups
    VLBC0422s/01: Thu 13:00–15:30 A16/213, M. Králíková
    VLBC0422s/02: Thu 16:00–18:30 A16/213, J. Tomandl
    VLBC0422s/03: Thu 13:00–15:30 A16/213, M. Králíková
    VLBC0422s/04: Mon 8:00–10:30 A16/213, J. Slanina
    VLBC0422s/05: Thu 13:00–15:30 A16/215, J. Gregorová
    VLBC0422s/06: Thu 16:00–18:30 A16/213, J. Tomandl
    VLBC0422s/07: Mon 8:00–10:30 A16/213, J. Slanina
    VLBC0422s/08: Thu 16:00–18:30 A16/215, J. Dostál
    VLBC0422s/09: Thu 16:00–18:30 A16/215, J. Dostál
    VLBC0422s/10: Thu 13:00–15:30 A16/215, J. Gregorová
    VLBC0422s/11: Mon 11:00–13:30 A16/213, H. Paulová, E. Táborská
    VLBC0422s/12: Mon 11:00–13:30 A16/213, H. Paulová, E. Táborská
    VLBC0422s/13: Tue 16:00–18:30 A16/215, M. Tomandlová
    VLBC0422s/14: Tue 16:00–18:30 A16/215, M. Tomandlová
    VLBC0422s/15: Tue 16:00–18:30 A16/213, H. Paulová, E. Táborská
    VLBC0422s/16: Tue 16:00–18:30 A16/213, H. Paulová, E. Táborská
    Prerequisites (in Czech)
    ( VLBI0222p Biology II-lect. || VSBI0222p Biology II-lect. ) && VLBF011p Biophysics-lect. && VLBC0321s Biochemistry I sem && VLBC0321c Biochemistry I && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
    Course Enrolment Limitations
    The course is only offered to the students of the study fields the course is directly associated with.
    fields of study / plans the course is directly associated with
    Course objectives
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Learning outcomes
    The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
    Syllabus
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods).
    • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion.
    • Blood glucose (sources, consumption, regulation). Diabetes mellitus.
    • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation.
    • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity.
    • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia.
    • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol.
    • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders.
    • Major functions of the kidney. Glomerular filtration.
    • Tubular resorption and secretion.
    • Neurotransmitters and hormone receptors. The most common signal pathways.
    • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism.
    • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin.
    • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literature
      required literature
    • Podklady pro semináře jsou ve studijních materiálech předmětu VSBC041s. The seminar files are available in IS, Study materials VSBC041s.
    Teaching methods
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Assessment methods
    course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.
    Language of instruction
    Czech
    Further comments (probably available only in Czech)
    Study Materials
    The course is taught annually.
    Information on the extent and intensity of the course: 45.
    Teacher's information
    http://www.med.muni.cz/toCP1250.cs/biochem/vyuka.html
    The course is also listed under the following terms Spring 2017, Spring 2018, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024.

    VLBC0422s Biochemistry I - seminar

    Faculty of Medicine
    Spring 2018
    Extent and Intensity
    0/3/0. 2 credit(s). Type of Completion: z (credit).
    Teacher(s)
    Ing. Martina Čarnecká, Ph.D. (seminar tutor)
    doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
    Mgr. Jana Gregorová, Ph.D. (seminar tutor)
    MUDr. Michaela Králíková, Ph.D. (seminar tutor)
    RNDr. Hana Paulová, CSc. (seminar tutor)
    doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
    Mgr. Jiří Slanina, Ph.D. (seminar tutor)
    prof. RNDr. Eva Táborská, CSc. (seminar tutor)
    doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
    Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
    MUDr. Lenka Gescheidtová, Ph.D. (assistant)
    MUDr. Miroslava Hlaváčová, Ph.D. (assistant)
    PharmDr. Katarína Kostolanská (assistant)
    Lenka Nerudová (assistant)
    Mgr. Lucie Novotná (assistant)
    Mgr. Anna Pleskačová, Ph.D. (assistant)
    MUDr. RNDr. Michal Řiháček, Ph.D., EuSpLM (assistant)
    Mgr. Roman Sándor, Ph.D. (assistant)
    Mgr. Jindra Smutná, Ph.D. (assistant)
    Mgr. Ondřej Wiewiorka, Ph.D. (assistant)
    Guaranteed by
    prof. RNDr. Eva Táborská, CSc.
    Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Timetable of Seminar Groups
    VLBC0422s/01: Thu 13:30–16:00 A16/213, J. Gregorová
    VLBC0422s/02: Thu 13:30–16:00 A16/213, J. Gregorová
    VLBC0422s/03: Thu 13:30–16:00 A16/213, J. Slanina
    VLBC0422s/04: Thu 13:30–16:00 A16/213, J. Slanina
    VLBC0422s/05: Thu 16:10–18:40 A16/213, J. Tomandl
    VLBC0422s/06: Thu 16:10–18:40 A16/213, J. Tomandl
    VLBC0422s/07: Thu 16:10–18:40 A16/213, J. Dostál
    VLBC0422s/08: Mon 7:30–10:00 A16/213, H. Paulová
    VLBC0422s/09: Mon 10:30–13:00 A16/213, M. Králíková
    VLBC0422s/10: Mon 10:30–13:00 A16/213, M. Králíková
    VLBC0422s/11: Mon 11:20–13:50 A16/213, J. Slanina
    VLBC0422s/12: Mon 11:20–13:50 A16/213, J. Slanina
    VLBC0422s/13: Mon 7:30–10:00 A16/213, H. Paulová
    VLBC0422s/14: Tue 15:00–17:30 A16/213, M. Tomandlová
    VLBC0422s/15: Tue 15:00–17:30 A16/213, M. Tomandlová
    VLBC0422s/16: Thu 16:10–18:40 A16/213, J. Dostál
    VLBC0422s/17: Fri 14:00–16:30 A16/213, E. Táborská
    VLBC0422s/18: Fri 14:00–16:30 A16/213, E. Táborská
    Prerequisites (in Czech)
    ( VLBI0222p Biology II-lect. || VSBI0222p Biology II-lect. ) && VLBF011p Biophysics-lect. && VLBC0321s Biochemistry I sem && VLBC0321c Biochemistry I && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
    Course Enrolment Limitations
    The course is only offered to the students of the study fields the course is directly associated with.
    fields of study / plans the course is directly associated with
    Course objectives
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Learning outcomes
    The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
    Syllabus
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods).
    • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion.
    • Blood glucose (sources, consumption, regulation). Diabetes mellitus.
    • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation.
    • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity.
    • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia.
    • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol.
    • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders.
    • Major functions of the kidney. Glomerular filtration.
    • Tubular resorption and secretion.
    • Neurotransmitters and hormone receptors. The most common signal pathways.
    • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism.
    • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin.
    • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literature
      required literature
    • Podklady pro semináře jsou ve studijních materiálech předmětu VSBC041s. The seminar files are available in IS, Study materials VSBC041s.
    Teaching methods
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Assessment methods
    course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.
    Language of instruction
    Czech
    Further Comments
    Study Materials
    The course is taught annually.
    Teacher's information
    http://www.med.muni.cz/toCP1250.cs/biochem/vyuka.html
    The course is also listed under the following terms Spring 2017, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024.

    VLBC0422s Biochemistry I - seminar

    Faculty of Medicine
    Spring 2017
    Extent and Intensity
    0/3/0. 2 credit(s). Type of Completion: z (credit).
    Teacher(s)
    Ing. Martina Čarnecká, Ph.D. (seminar tutor)
    doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
    MUDr. Lenka Gescheidtová, Ph.D. (seminar tutor)
    Mgr. Jana Gregorová, Ph.D. (seminar tutor)
    MUDr. Miroslava Hlaváčová, Ph.D. (seminar tutor)
    PharmDr. Katarína Kostolanská (seminar tutor)
    MUDr. Michaela Králíková, Ph.D. (seminar tutor)
    Mgr. Lucie Novotná (seminar tutor)
    RNDr. Hana Paulová, CSc. (seminar tutor)
    doc. Mgr. Ondřej Peš, Ph.D. (seminar tutor)
    Mgr. Anna Pleskačová, Ph.D. (seminar tutor)
    MUDr. RNDr. Michal Řiháček, Ph.D., EuSpLM (seminar tutor)
    Mgr. Roman Sándor, Ph.D. (seminar tutor)
    Mgr. Jiří Slanina, Ph.D. (seminar tutor)
    prof. RNDr. Eva Táborská, CSc. (seminar tutor)
    doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
    Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
    Lenka Nerudová (assistant)
    Guaranteed by
    prof. RNDr. Eva Táborská, CSc.
    Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
    Timetable of Seminar Groups
    VLBC0422s/01: Thu 13:30–16:00 A16/213, M. Králíková
    VLBC0422s/02: Thu 13:30–16:00 A16/213, M. Králíková
    VLBC0422s/03: Thu 13:30–16:00 A16/213, E. Táborská
    VLBC0422s/04: Thu 13:30–16:00 A16/213, E. Táborská
    VLBC0422s/05: Thu 16:10–18:40 A16/213, J. Slanina
    VLBC0422s/06: Thu 16:10–18:40 A16/213, J. Slanina
    VLBC0422s/07: Thu 16:10–18:40 A16/213, J. Dostál
    VLBC0422s/08: Mon 7:30–10:00 A16/213, H. Paulová
    VLBC0422s/09: Mon 10:30–13:00 A16/213, M. Králíková
    VLBC0422s/10: Mon 10:30–13:00 A16/213, M. Králíková
    VLBC0422s/11: Mon 11:20–13:50 A16/213, J. Tomandl
    VLBC0422s/12: Mon 11:20–13:50 A16/213, J. Tomandl
    VLBC0422s/13: Mon 7:30–10:00 A16/213, H. Paulová
    VLBC0422s/14: Tue 15:00–17:30 A16/213, M. Tomandlová
    VLBC0422s/15: Tue 15:00–17:30 A16/213, M. Tomandlová
    VLBC0422s/16: Thu 16:10–18:40 A16/213, J. Dostál
    VLBC0422s/17: Fri 13:30–16:00 A16/213, E. Táborská
    VLBC0422s/18: Fri 13:30–16:00 A16/213, E. Táborská
    Prerequisites (in Czech)
    ( VLBI0222p Biology II-lect. || VSBI0222p Biology II-lect. ) && VLBF011p Biophysics-lect. && VLBC0321s Biochemistry I sem && VLBC0321c Biochemistry I && VLFY0321c Physiology I - practice && VLFY0321s Physiology I - seminar
    Course Enrolment Limitations
    The course is only offered to the students of the study fields the course is directly associated with.
    fields of study / plans the course is directly associated with
    Course objectives
    Seminars are complementary to Biochemistry II lecture (VLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
    Learning outcomes
    The student is able to explain the interrelationship between the metabolism of nutrients under different states of the organism. Describes the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases. Understands and discusses principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations It discusses the composition of body fluids and their disorders in connection with the principles of homeostasis. It explains the principles of metabolism regulation at all levels.
    Syllabus
    • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods).
    • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion.
    • Blood glucose (sources, consumption, regulation). Diabetes mellitus.
    • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation.
    • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity.
    • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia.
    • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol.
    • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders.
    • Major functions of the kidney. Glomerular filtration.
    • Tubular resorption and secretion.
    • Neurotransmitters and hormone receptors. The most common signal pathways.
    • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism.
    • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin.
    • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
    Literature
      required literature
    • Podklady pro semináře jsou ve studijních materiálech předmětu VSBC041s. The seminar files are available in IS, Study materials VSBC041s.
    Teaching methods
    Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
    Assessment methods
    course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry I.
    Language of instruction
    Czech
    Further Comments
    The course is taught annually.
    Teacher's information
    http://www.med.muni.cz/toCP1250.cs/biochem/vyuka.html
    The course is also listed under the following terms Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024.
    • Enrolment Statistics (recent)