VLBI0121s Biology I - seminar

Faculty of Medicine
autumn 2020

The course is not taught in autumn 2020

Extent and Intensity
0/1/0. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Ondřej Slabý, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Prerequisites
Seminars revise the knowledge discussed at the Biology lectures - knowledge from the lectures is required.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- to revise and deepen the knowledge discussed at the respective Biology lecture
- to set this knowledge into a broader medical context
Learning outcomes
After completing the course the student will be able to:
- explain elementary processes taking place in cells and human body (gene expression, intercellular communication, cell differentiation, cell division, cell death) and their purposes
- express the basic coherence between malfunctioning cellular processes and development of diseases
- explain the general mechanism of pathogenesis in bacterial and viral diseases
- explain the general mechanism of pathogenesis of gene mutations and chromosome aberrations in humans, and illustrate it with examples
- explain the effects of therapies interacting with cellular processes; explain the principles of anti-bacterial, anti-viral and anti-mitotic treatment
Syllabus
  • Introduction to medical biology – from understanding the cellular principle to modern biomedicine
  • Bacteria and viruses – characteristics, reproduction strategies and principles of treatment
  • Structure, functions and function anomalies of eukaryotic cells
  • Cells in the context of the entire organism – principles of cell adhesion and intercellular communication
  • Cell signalling and the principle of cell differentiation
  • The importance of genetic information – the journey from a gene to protein; DNA replication
  • Cell cycle – molecular mechanisms of regulation and significance for oncology
  • Mitotic division in normal and cancer cells
  • Meiosis and the principle of genetic variability
  • The basics of genetics, the nature of dominance and recessivity
  • Genetics of human diseases – molecular principles of genetically determined disorders
  • Cell death – mechanisms and regulation of apoptosis and its significance for medicine
  • Epigenetics – the link between genes and environment
Literature
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
    not specified
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
Teaching methods
discussions, problem solving and interaction using a voting system
Assessment methods
Without examination - Biology I is continued with Biology II which is completed with a written examination test. Requirements for course completion: full attendance in the seminars.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 15.
Teacher's information
https://is.muni.cz/auth/el/1411/podzim2017/VLBI0121s/index.qwarp
The course is also listed under the following terms Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019.
  • Enrolment Statistics (autumn 2020, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2020/VLBI0121s