VLKB091 Clinical biochemistry

Faculty of Medicine
Spring 2009
Extent and Intensity
0/2/0. 1 credit(s). Type of Completion: k (colloquium).
Teacher(s)
doc. MUDr. Milan Dastych, CSc., MBA (lecturer)
MUDr. Michaela Králíková, Ph.D. (lecturer)
prof. MUDr. Vladimír Palyza, CSc. (lecturer)
doc. MUDr. Jaromír Sláma, CSc. (lecturer)
prof. MUDr. Vladimír Soška, CSc. (lecturer)
Lenka Nerudová (assistant)
Mgr. Jiří Slanina, Ph.D. (assistant)
doc. RNDr. Josef Tomandl, Ph.D. (assistant)
Guaranteed by
prof. MUDr. Vladimír Palyza, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: Lenka Nerudová
Prerequisites (in Czech)
( VLFA0822p Pharmacology II - L || VLFA0722p Pharmacology - L ) && VLVL7X61c Internal medicine part 1
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Hlavním cílem je získat poznatky ze základních oblastí klinické biochemie, aplikované v klinické praxi.
Syllabus
  • 1. Assessment and monitoring of nutritional status. Blood plasma proteins. Acute-phase reactants. Adipokines. Principles of nutritional support, enteral and parenteral nutrition. Dietary constituents providing a sufficient energy intake. 2. Energy output, nitrogen balance. Indications for nutritional support. Oxygen, transport and metabolism, tissue hypoxia. 3. Disorders of lipid and lipoprotein metabolism. 4. Ischemic heart disease, congestive cardiac failure. Potassium and magnesium homeostasis. 5. Disturbances of water and sodium balance. Plasma and urine osmolality. Plasma electrolytes in acid-base disorders. 6. Assessment of acid-base balance. Investigating an acid-base status, indications for blood acid-base and oxygen measurements, interpretation of results. 7. Laboratory evaluation of kidney function. Biochemical monitoring of acute and chronic renal failure, and of patients receiving haemodialysis. Urine sediment. 8. Investigation of liver and biliary tract diseases. Signs of the liver injury, differentiating of hyperbilirubinaemias, syndrome of biliary obstruction. 9. Clinical biochemistry of the GIT. Gastric acid secretion, maldigestion and malabsorption, assessment of pancreatic function. 10. Disorders of saccharide metabolism, diabetes mellitus. 11. Uric acid, hyperuricaemia. Renal tract stones. 12. Iron and essential microelements metabolism. 13. Laboratory assessment of thyroid and adrenal functions. 14. Calcium and phosphate metabolism. Biochemical markers of bone metabolism (in the assessment of osteoporosis). 15. Tumour markers. 16. Biological causes of variation of test results, effects of drugs on chemical tests.
Literature
  • RACEK, Jaroslav. Klinická biochemie. 2., přeprac. vyd. Praha: Galén, 2006. 329 s. ISBN 8072623249. info
  • SCHNEIDERKA, Petr. Kapitoly z klinické biochemie. 1. vyd. V Praze: Karolinum, 2000. 284 s. ISBN 8024601400. info
  • Klinická biochemie. Edited by Jaroslav Racek. 1. vyd. Praha: Galén, 1999. 317 s. ISBN 80-7262-023-1. info
  • RACEK, Jaroslav. Klinická biochemie (Clinical chemistry). 1st ed. Praha: Galén, 1999. 316 pp. ISBN 80-7262-023-1. info
  • RACEK, Jaroslav. Klinická biochemie. 1. vyd. Praha: Galén, 1999. 317 s. ISBN 8071849715. info
Assessment methods
oral examination - colloquium
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: in blocks.
Information on course enrolment limitations: kromě studentů LF maximálně 3 studenti MU v jednom běhu
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Spring 2007, Autumn 2007, Spring 2008, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023.
  • Enrolment Statistics (Spring 2009, recent)
  • Permalink: https://is.muni.cz/course/med/spring2009/VLKB091