ZLFA0521p Pharmacology I - lecture

Faculty of Medicine
Autumn 2008
Extent and Intensity
1/0/0. 0 credit(s). Type of Completion: -.
Teacher(s)
prof. MUDr. Alexandra Šulcová, CSc. (lecturer)
prof. MUDr. Eva McCaskey Hadašová, CSc. (lecturer)
MUDr. Jana Nováková, Ph.D. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
doc. Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
MVDr. Dagmar Vršková, Ph.D. (lecturer)
Guaranteed by
prof. MUDr. Alexandra Šulcová, CSc.
Department of Pharmacology – Theoretical Departments – Faculty of Medicine
Contact Person: prof. MUDr. Alexandra Šulcová, CSc.
Prerequisites (in Czech)
ZLPA0521c Pathology I - practice && ZLPF0521c Pathophysiol.I - practice
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
From the course on pharmacology students are expected to obtain: a) from lectures and seminars: a clarification of integration in the field of biomedical subjects such as chemistry, physiology, molecular biology, pathology and pathological physiology enabling them to understand why, what mechanism by, and what conditions on, drugs and their combinations may elicit therapeutic, adverse, and toxic effects. They will acquire an orientation in drug classes according to their main therapeutic indications with an attention paid to common drug-drug interactions, too. Information on drug development process, rules of preclinical and clinical drug testing will also be given. b) from practicals: a training in practical skills in "pharmacological thinking" in cases of need to make a choice of drug, dosing regimen, route and techniques of administration, and an elimination of adverse interactions with drugs simultaneously given.
Syllabus
  • (1) Pharmacology of hypothalamus and hypophysis functioning. Drugs indicated in disorders of skeletal homeostasis.
  • (2) Antihypertensives. Diuretics, antiadrenergics, vasodilators, combinative pharmacotherapy.
  • (3) Anti-anginal agents (nitrites, beta-adrenergic blockers, calcium entry blockers). Lipid lowering agents.
  • (4) Pharmacotherapy of heart failure. Inotropic drugs (digitalis, amrinone, dobutamine). Pharmacotherapy of cardiac arrythmias. I.A - affecting membrane functions, quinidine-like effects; I.B - affecting mebrane functions with anesthetic effects; I.C - lorcainide, flecainide, propafenone; II. - beta-blockers; III. - increasing APD; IV. - calcium channel antagonists.
  • (5) Introduction to psychopharmacology. Neurotransmitter mechanisms and specific neurotransmitter systems.
  • (6) Antipsychotics, treatment of psychosis, adverse effects. Drugs for affective (mood) disorders, Ist - III. (IV.)rd generations of antidepressants, anti-manic drugs.
  • (7) Nootropics. Anti-Parkinson pharmacotherapy, (dopaminergic drugs, central anticholinergic drugs). Drugs used in Alzheimer`s disease and other states of dementia.
  • (8) Drug addiction, mechanisms, treatment and prevention.
  • (9) Basic principles of pharmacoeconomics, types of pharmacoeconomic analyses and their relevant use in clinical practice.
Literature
  • LINCOVÁ, Dagmar and Hassan FARGHALI. Základní a aplikovaná farmakologie. 2., dopl. a přeprac. vyd. Praha: Galén, 2007, xxiv, 672. ISBN 9788072623730. info
  • ZELENKOVÁ, Olga and Alexandra ŠULCOVÁ. Speciální stomatologická receptura pro praktická cvičení z farmakologie (Special stomatological prescriptions for practicals in pharmacology). 2. přepracované vydání. Brno: Masarykova univerzita v Brně, 2000, 30 pp. ISBN 80-210-2433-X. info
  • http://portal.med.muni.cz/clanek-461-farmakovigilance-a-propagace-leciv.html
  • DOSTÁLEK, Miroslav, Jan JUŘICA, Eva JANOŠTÍKOVÁ and Lucia ZAHRADNÍKOVÁ. Farmakokinetika (Pharmacokinetics). ČR: Grada, 2006, 220 pp. Farmacie a farmakologie. ISBN 80-247-1464-7. info
  • http://portal.med.muni.cz/modules.php?name=News&file=article&sid=367
  • RANG, H. P. Rang and Dale's pharmacology. 6th ed. [S.l.]: Churchill Livingstone, 2007, xiii, 829. ISBN 9780443069116. info
  • Lippincott's Illustrated Reviews : Pharmacology : Special Millennium Update Autor: Mary Julia Mycek M.J. Richard A. HarveyR.A., Champe P.C. 2000. ISBN: 0781724139
  • Pharmaceutical Practice. Winfield, A.J. & Richards, R.M.E., eds. Churchill Livingstone. , 3rd Ed. 2004. ISBN 0443 07206 X
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?id=7lNQpLuETq4C&printsec=frontcover&dq=farmakologie&lr=&as_brr=3#PPA4,M1
  • Vybrané kapitoly z učebnice: http://books.google.cz/books?ct=result&q=farmakologie&lr=&as_brr=3&sa=N&start=0
  • Ritter, James M. - Lewis, Lionel D. - Mant, Timothy G.K. - Ferro, Albert. A Textbook of Clinical Pharmacology and Therapeutics, 5th Ed., Hodder Arnold, 2008. 465 s. ISBN 978-0-340-90046-8
Assessment methods
During the studying the student has to prove active knowledge of pharmacology acquired to get the credit. The student has to pass the prescription test and the final written exam - multiple-choice test.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Autumn 2006, Autumn 2007.
  • Enrolment Statistics (recent)
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