aVLBC0422s Biochemie II - seminář

Lékařská fakulta
jaro 2019
Rozsah
0/3/0. 45. 2 kr. Ukončení: z.
Vyučující
Ing. Martina Čarnecká, Ph.D. (cvičící)
doc. RNDr. Jiří Dostál, CSc. (cvičící)
MUDr. Michaela Králíková, Ph.D. (cvičící)
RNDr. Hana Paulová, CSc. (cvičící)
Mgr. Jiří Slanina, Ph.D. (cvičící)
prof. RNDr. Eva Táborská, CSc. (cvičící)
doc. RNDr. Josef Tomandl, Ph.D. (cvičící)
Mgr. Marie Tomandlová, Ph.D. (cvičící)
MUDr. Miroslava Hlaváčová, Ph.D. (pomocník)
PharmDr. Katarína Kostolanská (pomocník)
Lenka Nerudová (pomocník)
Garance
prof. RNDr. Eva Táborská, CSc.
Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
Dodavatelské pracoviště: Biochemický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh seminárních/paralelních skupin
aVLBC0422s/30: St 16:00–18:30 A16/213, J. Tomandl
aVLBC0422s/31: Po 16:00–18:30 A16/213, J. Dostál
aVLBC0422s/32: Po 10:00–12:30 A16/215, J. Tomandl
aVLBC0422s/33: Po 10:00–12:30 A16/215, J. Tomandl
aVLBC0422s/34: Po 16:00–18:30 A16/215, E. Táborská
aVLBC0422s/35: Po 16:00–18:30 A16/213, J. Dostál
aVLBC0422s/36: Út 11:00–13:30 A16/215, E. Táborská
aVLBC0422s/37: Po 16:00–18:30 A16/215, E. Táborská
aVLBC0422s/38: St 16:00–18:30 A16/213, J. Tomandl
Předpoklady
aVLBI0222p Biologie II - přednáška && aVLBF011p Biophysics - lecture && aVLBC0321s Biochemie I - sem. && aVLBC0321c Biochemie I - cvičení && aVLFY0321c Fyziologie I - cv. && aVLFY0321s Fyziologie I - sem.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
Seminars are complementary to Biochemistry II lecture (aVLBC0422p). At the end of the course students undestand principles of intermediary metabolism, characteristic features of metabolism of individual organs and tissues and metabolism at various conditions of organism (well fed state, fasting, starvation, metabolic stress, obesity, metabolic syndrome).
Výstupy z učení
The student is able:
- to explain the interrelationship between the metabolism of nutrients under different states of the organism.
- to describe the metabolic characteristics of major organs and tissues and major disorders, discusses their association with diseases.
- to understand and discuss principles of maintaining homeostasis and acid-base balance in the organism, including modeling situations
- to discuss the composition of body fluids and their disorders in connection with the principles of homeostasis.
- to explain the principles of metabolism regulation at all levels.
Osnova
  • Enzyme assays in clinical diagnostics. Methods in clinical biochemistry (photometry, electrophoretic methods). • Plasma lipoproteins, interconversions of lipoproteins. Cholesterol transport, balance of cholesterol intake and excretion. • Blood glucose (sources, consumption, regulation). Diabetes mellitus. • Proteins in nutrition. Absorption of amino acids, utilization of amino acids in tissues, blood transport of ammonia, the glutamine cycle. Hormonal regulation. • Integration of metabolism of nutrients: relationships among the major metabolic pathways in the fed state, post-absorptive state, prolonged starvation, obesity. • The liver functions – the role in metabolism of nutrients. Catabolism of haemoglobin, urobilinoids, the types of hyperbilirubinemia. • The liver functions – the role in metabolism of hormones, and vitamins. Metabolism of Fe. Biotransformation of xenobiotics. Metabolism of ethanol. • Water and mineral metabolism. Sodium and water homeostasis, osmolality and volume of water, regulation, disorders. Blood acid-base parameters. Transport of O2 a CO2. Metabolic processes producing and consuming H+. Buffer bases. Acid base disorders. • Major functions of the kidney. Glomerular filtration. • Tubular resorption and secretion. • Neurotransmitters and hormone receptors. The most common signal pathways. • Metabolism of Ca, Mg, P, F, I. Hormones important for their metabolism. • Metabolism of connective tissue. Extracellular matrix. Mineralisation of bone tissue, regulation. Biochemical markers of bone metabolism. Cartilage and skin. • Biochemistry of muscle work (skeletal, cardiac, smooth). Effect of NO.Energetics of muscle work.
Literatura
    povinná literatura
  • Seminar texts available in Information system
Výukové metody
Course is based on group discusion to the given topics. The outlines of discusion are in the recommended textbook. Complementary materials are available in section Study materials.
Metody hodnocení
course-unit credit. Conditions for giving the course-unit credit. Full attendance in all lessons. Three short tests are written during the semester. Students that will obtain 52/75 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. The limit for passing the credit test is 14 points. All absences must be made before writing the credit test. Students are allowed to repeat the test once. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Biochemistry II.
Vyučovací jazyk
Angličtina
Další komentáře
Předmět je vyučován každoročně.
Nachází se v prerekvizitách jiných předmětů
Předmět je zařazen také v obdobích jaro 2017, jaro 2018, jaro 2020, jaro 2021, jaro 2022, jaro 2023, jaro 2024.