aVLBI0222p Biologie II - přednáška

Lékařská fakulta
jaro 2017
Rozsah
1/0. 4 kr. Ukončení: zk.
Vyučující
Mgr. Kateřina Cetkovská, Ph.D. (přednášející)
prof. Ing. Petr Dvořák, CSc. (přednášející)
doc. Mgr. Lumír Krejčí, Ph.D. (přednášející)
RNDr. Pavel Krejčí, Ph.D. (přednášející)
Mgr. Vladimír Rotrekl, Ph.D. (přednášející)
prof. MUDr. Iva Slaninová, Ph.D. (přednášející)
prof. MUDr. David Šmajs, Ph.D. (přednášející)
RNDr. Mário Špírek, PhD. (přednášející)
Mgr. Stjepan Uldrijan, CSc. (přednášející)
Mgr. Kateřina Vopěnková, Ph.D. (přednášející)
Jana Růžičková (pomocník)
Mgr. Kateřina Straková, Ph.D. (pomocník)
Mgr. Martina Vráblíková (pomocník)
Garance
prof. Ing. Petr Dvořák, CSc.
Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: Mgr. Kateřina Cetkovská, Ph.D.
Dodavatelské pracoviště: Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh
Po 22. 5. až Pá 26. 5. St 13:00–15:50 B09/324, Po 20. 2. až Pá 19. 5. St 13:05–13:55 B11/334; a St 24. 5. 13:05–13:55 B11/235
Předpoklady
aVLBI0121c Biologie I - cvičení && aVLBI0121s Biologie I - seminář
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Výstupy z učení
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Osnova
  • 1. week:
  • DNA damage and repair – from molecular mechanisms to clinical significance (doc. Mgr. Lumír Krejčí, Ph.D.)
  • 2. week:
  • Introduction to cancer biology (Mgr. Stjepan Uldrijan, CSc.)
  • 3. week:
  • Oncogenes and oncoviruses in cancer transformation (Mgr. Stjepan Uldrijan, CSc.)
  • 4. week:
  • Tumour suppressor genes and their significance for diagnostics and therapy (Mgr. Stjepan Uldrijan, CSc.)
  • 5. week:
  • Paradigm of cancer stem cells and implications for anti-cancer therapies (doc. MUDr. Iva Slaninová, Ph.D.)
  • 6. týden:
  • Gene therapy – targets and strategies of molecular therapies (doc. MUDr. Iva Slaninová, Ph.D.)
  • 7. week:
  • Stem cells and tissue engineering – prospects of regenerative medicine (prof. Ing. Petr Dvořák, CSc.)
  • 8. week:
  • From a single cell to human I – introduction to developmental biology (Mgr. Vladimír Rotrekl, Ph.D.)
  • 9. week:
  • From a single cell to human II – molecular basis of mammalian development in health and disease (Mgr. Pavel Krejčí, Ph.D.)
  • 10. week:
  • Human genome and genomics in current biomedicine (prof. MUDr. David Šmajs, Ph.D.)
  • 11. week:
  • Human microbiome (prof. MUDr. David Šmajs, Ph.D.)
  • 12. week:
  • Bioinformatics in medicine – from molecules to populations (Mgr. Vladimír Rotrekl, Ph.D.)
  • 13. week:
  • Modern approaches in studying macromolecules and their use in current biomedicine (Mgr. Vladimír Rotrekl, Ph.D.)
  • 14. week:
  • Substitution lecture
Literatura
    povinná literatura
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
    doporučená literatura
  • HARDIN, Jeff, Gregory BERTONI a Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter a Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009, xix, 823. ISBN 9780470388259. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013, xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
    neurčeno
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005, xl, 1231. ISBN 080537146X. info
Výukové metody
lecture
Metody hodnocení
The course Biology II builds on knowledge gained from subject Biology I - lecture (aVLBI0121p) and is completed with a written examination test taken on computers. It contains questions based on the topics discussed in the lectures and practices. The students are expected to be able to solve given problems on their own, and to derive the solutions by their own consideration based on the theory discussed in the course of both semesters and supplemented by the recommended reading.
Vyučovací jazyk
Angličtina
Informace učitele
https://is.muni.cz/auth/el/1411/jaro2017/aVLBI0222p/index.qwarp
Students are obliged to follow the Interactive syllabus of the course where they can find all relevant information (schedule, substitutions, public holidays etc.), and also corresponding study literature for each week, and links to animations and videos relevant to the topic (https://is.muni.cz/auth/el/1411/jaro2017/aVLBI0222p/index.qwarp)
The two required text books can be borrowed from the Campus university library (https://kuk.muni.cz/?page=&lang=english). They are also available as an electronic books which can be read on computers in the university library:
Essential cell biology by Alberts to be found through e-prezencka (https://kuk.muni.cz/?page=9&lang=english)
Medical genetics at a glance by Pritchard to be found at http://discovery.muni.cz
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