aZLBI0121p Biologie I - přednáška

Lékařská fakulta
podzim 2016
Rozsah
1/0. 0 kr. Ukončení: z.
Vyučující
Mgr. Kateřina Cetkovská, Ph.D. (přednášející)
prof. Ing. Petr Dvořák, CSc. (přednášející)
doc. Mgr. Lumír Krejčí, Ph.D. (přednášející)
RNDr. Pavel Krejčí, Ph.D. (přednášející)
Mgr. Vladimír Rotrekl, Ph.D. (přednášející)
prof. MUDr. Iva Slaninová, Ph.D. (přednášející)
prof. MUDr. David Šmajs, Ph.D. (přednášející)
RNDr. Mário Špírek, PhD. (přednášející)
Mgr. Stjepan Uldrijan, CSc. (přednášející)
Mgr. Kateřina Vopěnková, Ph.D. (přednášející)
Jana Růžičková (pomocník)
Mgr. Kateřina Straková, Ph.D. (pomocník)
Mgr. Martina Vráblíková (pomocník)
Garance
prof. Ing. Petr Dvořák, CSc.
Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: Mgr. Kateřina Cetkovská, Ph.D.
Dodavatelské pracoviště: Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh
Čt 11:30–12:20 B11/334
Předpoklady
Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/anim/overview_ENG.qwarp) or similar, and knowledge of all previous lectures and practical classes of the subject. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Cíle předmětu
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Osnova
  • Week 1:
  • Introduction to medical biology - from understanding of cellular principle to modern biomedicine (prof. Ing. Petr Dvořák, CSc.)
  • Week 2:
  • Bacteria and viruses – characteristics, reproduction strategies and principles of treatment (Mgr. Kateřina Vopěnková, Ph.D.)
  • Week 3:
  • Structure, functions and function anomalies of eukaryotic cells (Mgr. Kateřina Cetkovská, Ph.D.)
  • Week 4:
  • Cells in the context of the entire organism – principles of cell adhesion and intercellular communication (Mgr. Kateřina Cetkovská, Ph.D.)
  • Week 5:
  • Cell signalling and the principle of cell differentiation (Mgr. Kateřina Vopěnková, Ph.D.)
  • Week 6:
  • Cell death – mechanisms and regulation of apoptosis and its significance for medicine (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 7:
  • The importance of genetic information – the journey from a gene to protein; DNA replication (RNDr. Mário Špírek, Ph.D.)
  • Week 8:
  • Cell cycle – molecular mechanisms of regulation and significance for oncology (Mgr. Stjepan Uldrijan, CSc.)
  • Week 9:
  • Mitotic division in normal and cancer cells (Mgr. Vladimír Rotrekl, Ph.D.)
  • Week 10:
  • substitution week - no lecture
  • Week 11:
  • Meiosis and the principle of genetic variability (Mgr. Vladimír Rotrekl, Ph.D.)
  • Week 12:
  • The basics of genetics, the nature of dominance and recessivity (Mgr. Kateřina Vopěnková, Ph.D.)
  • Week 13:
  • Genetics of human diseases – molecular principles of genetically determined diseases (doc. MUDr. Iva Slaninová, Ph.D.)
  • Week 14:
  • Epigenetics – the link between genes and environment (Mgr. Stjepan Uldrijan, CSc.)
  • Week 15:
  • substitution lecture
Literatura
    povinná literatura
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
    doporučená literatura
  • HARDIN, Jeff, Gregory BERTONI a Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter a Michael J. SIMMONS. Principles of genetics. 5th ed. Hoboken: John Wiley & Sons, Inc, 2009, xix, 823. ISBN 9780470388259. info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013, xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
  • CAMPBELL, Neil A. Biology. Edited by Jane B. Reece. 7th ed. San Francisco: Pearson/Benjamin Cummings, 2005, xl, 1231. ISBN 080537146X. info
Výukové metody
lecture
Metody hodnocení
Lecture attendance is optional. Students continue with following subjects without proof of this semester's knowledge. Biology I (aZLBI0121p) is followed by Biology II (aZLBI0222p) that is completed with a written examination test. The test is based on knowledge of all topics from both semesters (lectures, practices).
Vyučovací jazyk
Angličtina
Navazující předměty
Informace učitele
https://is.muni.cz/auth/el/1411/podzim2016/aZLBI0121p/index.qwarp
Students are obliged to follow the Interactive syllabus of the course where they can find all relevant information (schedule, substitutions, public holidays etc.), and also corresponding study literature for each week, and links to animations and videos relevant to the topic (https://is.muni.cz/auth/el/1411/podzim2016/aZLBI0121p/index.qwarp)
The two required text books can be borrowed from the Campus university library (https://kuk.muni.cz/?page=&lang=english). They are also available as an electronic books which can be read on computers in the university library:
Essential cell biology by Alberts to be found through e-prezencka (https://kuk.muni.cz/?page=9&lang=english)
Medical genetics at a glance by Pritchard to be found at http://discovery.muni.cz
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Předmět je vyučován každoročně.
Předmět je zařazen také v obdobích podzim 2015, podzim 2017, podzim 2018, podzim 2019, podzim 2020, podzim 2021, podzim 2022, podzim 2023.