F1OC1_15 Organic Chemistry

Faculty of Pharmacy
Spring 2020
Extent and Intensity
5/4/0. 10 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Pavel Bobáľ, CSc. (lecturer)
doc. Ing. Pavel Bobáľ, CSc. (seminar tutor)
Mgr. Aleš Kroutil, Ph.D. (seminar tutor)
Mgr. Petr Mokrý, Ph.D. (seminar tutor)
PharmDr. Jan Otevřel, Ph.D. (seminar tutor)
Mgr. Hana Pížová, Ph.D. (seminar tutor)
Guaranteed by
doc. Ing. Pavel Bobáľ, CSc.
Department of Chemical Drugs – Departments – Faculty of Pharmacy
Prerequisites
The knowledge of basics of inorganic chemistry.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Organic chemistry gives students information about the fundamentals of organic compounds structure, their reactions, and underling reaction mechanism. Organic chemistry is essential for many other disciplines, such as biochemistry, analytical chemistry, pharmaceutical chemistry, physiology, pharmacology and other health and biological studies. Close attention is paid to the interrelation between organic chemistry and these disciplines.
Learning outcomes
Understanding of fundamentals of organic chemistry, understanding of structure and reactivity of organic compounds, knowledge of the basis of IUPAC nomenclature of organic compounds and principals of stereochemistry.
Syllabus
  • 1 Structure and Bonding
    2 Polar Covalent Bonds, Acids and Bases
    3 Organic Compounds: Alkanes and Their Stereochemistry
    4 Organic Compounds: Cycloalkanes and Their Stereochemistry
    5 An Overview of Organic Reactions
    6 Alkenes: Structure, Reactivity, and reactions
    7 Alkynes: An Introduction to Organic Synthesis
    8 Stereochemistry at Tetrahedral Centers
    9 Organohalides, Reactions of Alkyl Halides: Nucleophilic Substitutions and Eliminations
    10 Structure Determination: MS, IR, and NMR
    11 Conjugated Compounds and Ultraviolet Spectroscopy
    12 Benzene and Aromaticity, Chemistry of Benzene: Electrophilic Aromatic Substitution
    13 Alcohols and Phenols
    14 Ethers and Epoxides, Thiols and Sulfides
    15 Carbonyl Compounds, Aldehydes and Ketones: Nucleophilic Addition Reactions
    16 Carboxylic Acids and Nitriles
    17 Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
    18 Carbonyl Alpha-Substitution Reactions, Carbonyl Condensation Reactions
    19. Carbonic acid derivatives
    20 Nitrogen Compounds
    21 Organometallic Compounds
    22 Heterocycles: 3-,4-,7- and more membered
    23 Heterocycles: 5- and 6-membered
    24 Photochemistry, Orbitals and Organic Chemistry: Pericyclic Reactions
    25 Biomolecules: Carbohydrates
    26 Biomolecules: Amino Acids, Peptides, and Proteins
    27 Biomolecules: Lipids
    28 Biomolecules: Nucleic Acids
    29 Synthetic Polymers
    30 Nomenclature of Organic Compounds
Literature
    required literature
  • Bobáľ, P., Otevřel, J. Návody k laboratorním cvičením z organické chemie. Veterinární a farmaceutická univerzita Brno, 2014. ISBN 978-80-7305-747-3. info
  • Bobáľ, P., Pížová, H. Organická chemie - pracovní sešit. Veterinární a farmaceutická univerzita Brno, 2014. ISBN 978-80-7305-746-6. info
  • McMurry, S. Studijní příručka a řešené příklady k 6. vydání učebnice J. McMurry "Organická chemie". VŠCHT Praha, 2009. ISBN 978-80-7080-723-1. info
  • Liška F. Konstituce, konformace, konfigurace v názvech organických sloučenin. Vydavatelství V$CHT Praha, 2008. ISBN 978-80-7080-640-1. info
  • McMurry, J. Organická chemie. VŠCHT Praha, 2007. ISBN 978-80-7080-637-1. info
    recommended literature
  • FIKR, J., KAHOVEC, J. Názvosloví organické chemie. Rubico Olomouc, 2002. ISBN 80-85839-71-7. info
  • DEVÍNSKÝ, F. a kol. ORGANICKÁ CHÉMIA pre farmaceutov. Osveta Martin, 2001. ISBN 80-8063-056-9. info
  • Akademie věd ČR. PRŮVODCE NÁZVOSLOVÍM ORGANICKÝCH SLOUČENIN podle IUPAC - doporučení 1993. Academia Praha, 2000. ISBN 80-200-0724-5. info
  • POTÁČEK, M. ORGANICKÁ CHEMIE pro biology. MU Brno, 1995. ISBN 80-210-1125-4. info
  • ČERVINKA, O., DĚDEK, V., FERLES, M. ORGANICKÁ CHEMIE. Informatorium Praha, 1991. info
  • ČELADNÍK, M. a kol. ORGANICKÁ CHEMIE. Avicenum Praha, 1990. ISBN 08-088-90. info
    not specified
  • ČELECHOVSKÁ, O. ORGANICKÁ CHEMIE I. - Stručné základy názvosloví. VFU, 2003. ISBN 80-7305-468-X. info
  • ČELECHOVSKÁ, O. Návody k laboratornímu cvičení z organické chemie. VFU Brno, 1999. ISBN 80-85114-46-1. info
  • WAISSER, K. ORGANICKÁ CHEMIE I. A II. Karolinum, 1999. ISBN 80-7184-874-3. info
  • WAISSER, K. BIOORGANICKÁ CHEMIE. Karolinum, 1998. ISBN 80-7184-547-7. info
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
Teacher's information
https://amos.vfu.cz/moodle/course/view.php?id=856
Students are required to complete a credit in laboratory practicals and to achieve minimum 60 % of total points of all tests.
To pass the exam student must receive more than 60 % of points of written exam.
The course is also listed under the following terms Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (Spring 2020, recent)
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