F1SB1_16 Structural Biology and Proteomics

Faculty of Pharmacy
Spring 2020
Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
RNDr. Jiří Jelínek, Ph.D. (lecturer)
prof. Ing. René Kizek, DrSc., MBA (lecturer)
Guaranteed by
RNDr. Jiří Jelínek, Ph.D.
Department of Molecular Pharmacy – Departments – Faculty of Pharmacy
Prerequisites
knowledge of subject in range of lectures
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Sequencing of human genome significantly extended scale for development
of new drugs. A structure-genomics has been created to help to determine
function of individual genes by high-throughput protein crystallography.
Experimentally determined structures of proteins and nucleic acids and
their complexes with inhibitors, substrates and drugs become the basis
for rational drug design. Big pharmaceutic corporations formed large and
expensive laboratories of structure biology. For this reason it is
necessary to introduce these progressive methods into pedagogic curriculum.
Syllabus
  • Lectures
    1. Structure of nucleic acids.
    2. General structure of proteins.
    3. Structure and function of cell organelles and compartments.
    4. Structure and function of selected cellular receptors.
    5. Structure and function of basic cytokines.
    6. Structure and function of immunoglobulins
    7. Methods of structure analysis
Literature
    recommended literature
  • &. Alberts et al.: Základy buněčné biologie. 2001, Espero Publishing, Ústí nad Labem. Nečas O a kol.: Obecná biologie. 2000, H a H, Jinočany. Šmarda J.: Genetika pro gymnázia. 2003, Fortuna Praha. &. info
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
The exam will be done in written form.
The course is also listed under the following terms Spring 2021, Spring 2022, Spring 2023.
  • Enrolment Statistics (Spring 2020, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2020/F1SB1_16