FaF:FALF1_13 Theory of Dosage Forms - Course Information
FALF1_13 Theory of Dosage Forms
Faculty of PharmacyAutumn 2021
- Extent and Intensity
- 2/1/0. 4 credit(s). Type of Completion: zk (examination).
Taught in person. - Teacher(s)
- prof. PharmDr. Mgr. David Vetchý, Ph.D. (lecturer)
doc. PharmDr. Jan Gajdziok, Ph.D. (lecturer)
PharmDr. Jan Elbl, Ph.D. (lecturer)
doc. Mgr. Jan Muselík, Ph.D. (seminar tutor)
prof. PharmDr. Mgr. David Vetchý, Ph.D. (seminar tutor) - Guaranteed by
- prof. PharmDr. Mgr. David Vetchý, Ph.D.
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy - Timetable
- Tue 15:10–16:50 posluchárna, 122
- Timetable of Seminar Groups:
- Prerequisites (in Czech)
- FAKULTA ( FaF ) || OBOR ( MUSFaF )
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Multidisciplinary studies at Faculty of Pharmacy (programme CST, KOS)
- Pharmacy (programme FaF, M-FARMA)
- Course objectives
- Obligatory subject presenting the basics in medicament formulation, methods and processes useful for their development, polymers suitable for medical form design, stability testing.
- Learning outcomes
- After completing the course, the student will be able to:
- identify and classify the dosage form into one of the three generations according to the nature of the drug release;
- describe procedures leading to increased bioavailability of drugs;
- describe the production and evaluation of mucoadhesive systems, ion exchangers and biological dosage forms;
- describe the principles of 3D printing for the preparation of dosage forms;
- describe in vitro-in vivo modelsv in drug development - Syllabus
- LECTURES:
- Introduction into the pharmaceutical technology, medical forms and drug delivery, the importance of biopharmacy and pharmacokinetics in formulation and development of pharmaceuticals. Generation of medical forms. Medical forms of the first generation.
- Medical forms of the second and the third generation.
- Physico-chemical factors influencing the effect of the drug.
- Biological factors influencing the effect of the drug.
- Preformulation studies, drug formulation, drug validation.
- Increasing bioavailability of poorly water soluble drugs by their modification.
- Increasing bioavailability of poorly water soluble drugs by technological methods facilitating drug dissolution.
- Lipophilic formulations for increasing bioavailability of poorly water-soluble drugs.
- Liquid-solid systems and their application in pharmacy. Medical forms based on these systems.
- Mucoadhesive systems and their application in pharmacy. Medical forms based on these systems.
- 3D printing and its application in pharmacy. Medical forms based on this technology.
- Ion exchangers and their application in pharmacy. Medical forms based on ion exchangers. Production of biological dosage forms.
- In vitro in vivo models in drug development.
PRACTICAL TRAINING: - Surface tension measurement by stalagmometric method.
- Preparation and evaluation of mucoadhesive oral films (MOF).
- Evaluation of aggregate state of suspension.
- Literature
- required literature
- Sinko, P.T., Singh, Y. Martin's Physical Pharmacy 2011. Online info
- Teaching methods
- lectures, laboratory exercises
- Assessment methods
- credit, oral exam
- Language of instruction
- English
- Further comments (probably available only in Czech)
- The course can also be completed outside the examination period.
- Teacher's information
- Lectures recommended due to lack of suitable literature. Participate in exercises in the full range given by the syllabus and properly prepare protocols from laboratory exercises. Demonstrate ongoing knowledge in the preparation for laboratory exercices. The condition for participation in the exam is to obtain a credit.
- Enrolment Statistics (Autumn 2021, recent)
- Permalink: https://is.muni.cz/course/pharm/autumn2021/FALF1_13