FARF1_13 Radiopharmaceuticals

Faculty of Pharmacy
Spring 2020
Extent and Intensity
1/1/0. 3 credit(s). Type of Completion: zk (examination).
Guaranteed by
PharmDr. Michal Budinský
Department of Pharmaceutical Technology – Departments – Faculty of Pharmacy
Prerequisites

Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Short synopsis outlining contents and aim of the subject:
Aim of subject: Subject focused on special requirements for handling the radioactive substances in manufacturing of medicinal preparation in required dosage form and on relevant control procedures. Subject introduces into usage of these drugs in diagnostics and therapy.
Syllabus
  • Lectures:
    1st seminar: 28-Feb-20 13:45-15:15 Introduction into practical training from Radiopharmaceuticals, effect of radiation on organism, radiation protection and its application in practice. (Dr. Budinský)
    1st lecture: 28-Feb-20 15:15-16:45 Preparation of radiopharmaceuticals and their quality evaluation, dosage forms of radiopharmaceuticals. Radiopharmaceuticals in therapy. (Dr. Budinský)
    2nd lecture: 13-Mar-20 13:45-15:15 Kinetic of radiopharmaceuticals. Radioactivity use in chemistry. (Dr. Macků)
    3rd lecture: 13-Mar-20 15:15-16:45 Legislation in radiopharmacy, production and distribution of radiopharmaceuticals. (Dr. Růžičková)
    4th lecture: ___ Apr. 2020 13:45-15:15 Investigation of patient at nuclear medicine departement, SPECT, PET, hybride systems, PET and protone therapy. (Ing. Bartl)
    5th lecture: ___May 2020 13:45-16:00 Clinical use of radiopharmaceuticals in diagnosis. New radiopharmaceuticals. (Dr. Budinský)
    Terms of lectures will be specified at the beginning of semester.

    Practice:
    radiation protection principles.
    personnel, documentation.
    preparation and QC of radiopharmaceuticals
    preparation of 99mTc and 111In radiopharmaceuticals in SPECT dg.
    preparation of 18F radiopharmaceuticals in PET dg.
    oncological and non-oncological radiopharmaceuticals in diagnosis and therapy.

    For every practice two students are maximum, 60 minutes.
    Terms: the whole summer semester 2020.
Literature
    recommended literature
  • Komárek, P., Rabišková, M. Technologie léků. Galén, Praha. ISBN 80-7262-423-7. 2006. info
  • Gopal B. Saha,. Fundamentals of Nuclear Pharmacy. Springer-Verlag New York. ISBN 0-387-40360-4. 2004. info
Teaching methods (in Czech)
Přednášení
Monologická (výklad, přednáška, instruktáž)
Assessment methods (in Czech)
Písemná zkouška
Language of instruction
English
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
Credit:
involvement in seminar and practice, radiation protection test
Exam:
written test

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