Bi9325 Human Molecular Genetics

Faculty of Science
Autumn 2024
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
Mgr. Jan Smetana, Ph.D. (lecturer)
doc. RNDr. Petra Bořilová Linhartová, Ph.D., MBA (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Hana Zelená (assistant)
Guaranteed by
doc. RNDr. Petr Kuglík, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6401 Bc Thesis II || Bi3002 Bc thesis EMB 2 || Bi6491 Bachelor Thesis LGMD II || Bi6005 Bc. thesis II || Bi6006 Bc. thesis anim. phys. II || Bi6007 Bc. thesis || Bi6122 Bachelor thesis HB II || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 6 fields of study the course is directly associated with, display
Course objectives
The aim of this course is to provide a molecular-genetic insight into selected areas of human genetics.
Learning outcomes
At the end of this course, students should be able to describe the structure of the human genome; to apply the principles of methods used in analysis of human genome; to understand molecular principles of human genetic diseases (monogenic and polygenic); to formulate the principles of human pharmacogenetics and gene therapy; to be familiarised with base of forensic genetics.
Syllabus
  • 1. Human Genome Project 2. Mutations and polymorphisms of human DNA. Molecular aspects of monogenic diseases. 3. Structural genome variability and rare chromosomal diseases 4. Molecular patho(physio)logy 5. Genetics and complex diseases 6. Gene therapy 7. Pharmacogenetics 8. Genetics and cancer 9. Clinical molecular diagnosis 10. Genetics and forensic medicine 11. Educational excursion to Department of Forensic Medicine 12. News in Human Genetics - presentations of well-known experts
Literature
  • STRACHAN, T. and Andrew P. READ. Human molecular genetics. 4th ed. New York: Garland Science, 2011, xxv, 781. ISBN 9780815341499. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from the answers.
Language of instruction
Czech
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023.

Bi9325 Human Molecular Genetics

Faculty of Science
Autumn 2023
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
Mgr. Jan Smetana, Ph.D. (lecturer)
doc. RNDr. Petra Bořilová Linhartová, Ph.D., MBA (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Hana Zelená (assistant)
Guaranteed by
doc. RNDr. Petr Kuglík, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Tue 13:00–14:50 B11/305
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6401 Bc Thesis II || Bi3002 Bc thesis EMB 2 || Bi6491 Bachelor Thesis LGMD II || Bi6005 Bc. thesis II || Bi6006 Bc. thesis anim. phys. II || Bi6007 Bc. thesis || Bi6122 Bachelor thesis HB II || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 6 fields of study the course is directly associated with, display
Course objectives
The aim of this course is to provide a molecular-genetic insight into selected areas of human genetics.
Learning outcomes
At the end of this course, students should be able to describe the structure of the human genome; to apply the principles of methods used in analysis of human genome; to understand molecular principles of human genetic diseases (monogenic and polygenic); to formulate the principles of human pharmacogenetics and gene therapy; to be familiarised with base of forensic genetics.
Syllabus
  • 1. Human Genome Project 2. Mutations and polymorphisms of human DNA. Molecular aspects of monogenic diseases. 3. Structural genome variability and rare chromosomal diseases 4. Molecular patho(physio)logy 5. Genetics and complex diseases 6. Gene therapy 7. Pharmacogenetics 8. Genetics and cancer 9. Clinical molecular diagnosis 10. Genetics and forensic medicine 11. Educational excursion to Department of Forensic Medicine 12. News in Human Genetics - presentations of well-known experts
Literature
  • STRACHAN, T. and Andrew P. READ. Human molecular genetics. 4th ed. New York: Garland Science, 2011, xxv, 781. ISBN 9780815341499. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from the answers.
Language of instruction
Czech
Further Comments
Study Materials
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2024.

Bi9325 Human Molecular Genetics

Faculty of Science
Autumn 2022
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
doc. RNDr. Petra Bořilová Linhartová, Ph.D., MBA (lecturer)
Hana Zelená (assistant)
Guaranteed by
doc. RNDr. Petr Kuglík, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Tue 13:00–14:50 B11/305
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6401 Bc Thesis II || Bi3002 Bc thesis EMB 2 || Bi6491 Bachelor Thesis LGMD II || Bi6005 Bc. thesis II || Bi6006 Bc. thesis anim. phys. II || Bi6007 Bc. thesis || Bi6122 Bachelor thesis HB II || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 6 fields of study the course is directly associated with, display
Course objectives
The aim of this course is to provide a molecular-genetic insight into selected areas of human genetics.
Learning outcomes
At the end of this course, students should be able to describe the structure of the human genome; to apply the principles of methods used in analysis of human genome; to understand molecular principles of human genetic diseases (monogenic and polygenic); to formulate the principles of human pharmacogenetics and gene therapy; to be familiarised with base of forensic genetics.
Syllabus
  • 1. Human Genome Project 2. Mutations and polymorphisms of human DNA. Molecular aspects of monogenic diseases. 3. Structural genome variability and rare chromosomal diseases 4. Molecular patho(physio)logy 5. Genetics and complex diseases 6. Gene therapy 7. Pharmacogenetics 8. Genetics and cancer 9. Clinical molecular diagnosis 10. Genetics and forensic medicine 11. Educational excursion to Department of Forensic Medicine 12. News in Human Genetics - presentations of well-known experts
Literature
  • STRACHAN, T. and Andrew P. READ. Human molecular genetics. 4th ed. New York: Garland Science, 2011, xxv, 781. ISBN 9780815341499. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from the answers.
Language of instruction
Czech
Further Comments
Study Materials
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2023, Autumn 2024.

Bi9325 Human Molecular Genetics

Faculty of Science
autumn 2021
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
doc. RNDr. Petra Bořilová Linhartová, Ph.D., MBA (lecturer)
Hana Zelená (assistant)
Guaranteed by
doc. RNDr. Petr Kuglík, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Tue 13:00–14:50 B11/305
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6401 Bachelor Thesis II || Bi3002 Bc thesis EMB 2 || Bi6491 Bachelor Thesis LGMD II || Bi6005 Bc. thesis II || Bi6006 Bc. thesis anim. phys. II || Bi6007 Bc. thesis || Bi6122 Bachelor thesis HB II || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 6 fields of study the course is directly associated with, display
Course objectives
The aim of this course is to provide a molecular-genetic insight into selected areas of human genetics.
Learning outcomes
At the end of this course, students should be able to describe the structure of the human genome; to apply the principles of methods used in analysis of human genome; to understand molecular principles of human genetic diseases (monogenic and polygenic); to formulate the principles of human pharmacogenetics and gene therapy; to be familiarised with base of forensic genetics.
Syllabus
  • 1. Human Genome Project 2. Mutations and polymorphisms of human DNA. Molecular aspects of monogenic diseases. 3. Structural genome variability and rare chromosomal diseases 4. Molecular patho(physio)logy 5. Genetics and complex diseases 6. Gene therapy 7. Pharmacogenetics 8. Genetics and cancer 9. Clinical molecular diagnosis 10. Genetics and forensic medicine 11. Educational excursion to Department of Forensic Medicine 12. News in Human Genetics - presentations of well-known experts
Literature
  • STRACHAN, T. and Andrew P. READ. Human molecular genetics. 4th ed. New York: Garland Science, 2011, xxv, 781. ISBN 9780815341499. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from the answers.
Language of instruction
Czech
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human Molecular Genetics

Faculty of Science
Autumn 2020
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Taught online.
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
doc. RNDr. Petra Bořilová Linhartová, Ph.D., MBA (lecturer)
Hana Zelená (assistant)
Guaranteed by
doc. RNDr. Petr Kuglík, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Tue 13:00–14:50 prace doma
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of Special biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 6 fields of study the course is directly associated with, display
Course objectives
The aim of this course is to provide a molecular-genetic insight into selected areas of human genetics.
Learning outcomes
At the end of this course, students should be able to describe the structure of the human genome; to apply the principles of methods used in analysis of human genome; to understand molecular principles of human genetic diseases (monogenic and polygenic); to formulate the principles of human pharmacogenetics and gene therapy; to be familiarised with base of forensic genetics.
Syllabus
  • 1. Human Genome Project 2. Mutations and polymorphisms of human DNA. Molecular aspects of monogenic diseases. 3. Structural genome variability and rare chromosomal diseases 4. Molecular patho(physio)logy 5. Genetics and complex diseases 6. Gene therapy 7. Pharmacogenetics 8. Genetics and cancer 9. Clinical molecular diagnosis 10. Genetics and forensic medicine 11. Educational excursion to Department of Forensic Medicine 12. News in Human Genetics - presentations of well-known experts
Literature
  • STRACHAN, T. and Andrew P. READ. Human molecular genetics. 4th ed. New York: Garland Science, 2011, xxv, 781. ISBN 9780815341499. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from the answers.
Language of instruction
Czech
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human Molecular Genetics

Faculty of Science
Autumn 2019
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Hana Zelená (assistant)
Guaranteed by
doc. RNDr. Petr Kuglík, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Tue 13:00–14:50 B11/305
  • Timetable of Seminar Groups:
Bi9325/Exkurze_na_USL: No timetable has been entered into IS.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of Special biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 6 fields of study the course is directly associated with, display
Course objectives
The aim of this course is to provide a molecular-genetic insight into selected areas of human genetics.
Learning outcomes
At the end of this course, students should be able to describe the structure of the human genome; to apply the principles of methods used in analysis of human genome; to understand molecular principles of human genetic diseases (monogenic and polygenic); to formulate the principles of human pharmacogenetics and gene therapy; to be familiarised with base of forensic genetics.
Syllabus
  • 1. Human Genome Project 2. Mutations and polymorphisms of human DNA. Molecular aspects of monogenic diseases. 3. Structural genome variability and rare chromosomal diseases 4. Molecular patho(physio)logy 5. Genetics and complex diseases 6. Gene therapy 7. Pharmacogenetics 8. Genetics and cancer 9. Clinical molecular diagnosis 10. Genetics and forensic medicine 11. Educational excursion to Department of Forensic Medicine 12. News in Human Genetics - presentations of well-known experts
Literature
  • STRACHAN, T. and Andrew P. READ. Human molecular genetics. 4th ed. New York: Garland Science, 2011, xxv, 781. ISBN 9780815341499. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from the answers.
Language of instruction
Czech
Further Comments
Study Materials
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2018
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Hana Zelená (assistant)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Mon 24. 9. to Fri 14. 12. Tue 13:00–14:50 B11/305
  • Timetable of Seminar Groups:
Bi9325/Exkurze_USL: No timetable has been entered into IS.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of Special biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide a molecular-genetic insight into selected areas of human genetics.
Learning outcomes
At the end of this course, students should be able to describe the structure of the human genome; to apply the principles of methods used in analysis of human genome; to understand molecular principles of human genetic diseases (monogenic and polygenic); to formulate the principles of human pharmacogenetics and gene therapy; to be familiarised with base of forensic genetics.
Syllabus
  • 1. Genetics and cancer 2. Epigenetic proceses and DNA reparation 3. Molecular pathology 4. Gene therapy 5. Pharmacogenetics 6. Progress in prenatal diagnosis 7. Whole genome methods in preimplantation genetic diagnosis 8. NGS in human genetics 9. Genetics and complex diseases 10. Structural genome variability and rare chromosomal diseases 11. Genetics and forensic medicine 12. Genetic diseases in famous people
Literature
  • STRACHAN, T. and Andrew P. READ. Human molecular genetics. 4th ed. New York: Garland Science, 2011, xxv, 781. ISBN 9780815341499. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from the answers.
Language of instruction
Czech
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
autumn 2017
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Hana Zelená (assistant)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Mon 18. 9. to Fri 15. 12. Tue 13:00–14:50 B11/305
  • Timetable of Seminar Groups:
Bi9325/01: No timetable has been entered into IS.
Bi9325/02: No timetable has been entered into IS.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of Special biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the principles of human pharmacogenetics, gene therapy and forensic genetics.
Syllabus
  • Structure and expression of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2016
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Petr Kuglík, CSc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Hana Zelená (assistant)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Mon 19. 9. to Sun 18. 12. Tue 13:00–14:50 B11/235
  • Timetable of Seminar Groups:
Bi9325/Exkurze_USL_2016: No timetable has been entered into IS.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Medical genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of Special biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || Bi6088 Bc. state exam Klin.Gen.Diagn. || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the principles of human pharmacogenetics, gene therapy and forensic genetics.
Syllabus
  • Structure and expression of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2015
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Mgr. Aneta Mikulášová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Tue 13:00–14:50 B11/235
  • Timetable of Seminar Groups:
Bi9325/01: No timetable has been entered into IS. A. Mikulášová
Bi9325/02: No timetable has been entered into IS. A. Mikulášová
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of General biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the principles of human pharmacogenetics, gene therapy and forensic genetics.
Syllabus
  • Structure and expression of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2014
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Mgr. Aneta Mikulášová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Tue 14:00–15:50 B11/235
  • Timetable of Seminar Groups:
Bi9325/01: No timetable has been entered into IS. A. Mikulášová
Bi9325/02: No timetable has been entered into IS. A. Mikulášová
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of General biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the principles of human pharmacogenetics, gene therapy and forensic genetics.
Syllabus
  • Structure and expression of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2013
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Mgr. Aneta Mikulášová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Mon 16. 9. to Fri 6. 12. Tue 13:00–14:50 B11/235
  • Timetable of Seminar Groups:
Bi9325/01: No timetable has been entered into IS.
Bi9325/02: No timetable has been entered into IS.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of General biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the principles of human pharmacogenetics, gene therapy and forensic genetics.
Syllabus
  • Structure and expression of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2012
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Tue 13:00–14:50 B11/235
  • Timetable of Seminar Groups:
Bi9325/01: No timetable has been entered into IS. V. Vallová
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of General biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the priciples of human pharmacogenetics, gene therapy and forenzic genetics.
Syllabus
  • Structure and expresion of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2011
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
přednášející z LF MU (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Timetable
Tue 13:00–14:50 B11/235
  • Timetable of Seminar Groups:
Bi9325/01: No timetable has been entered into IS.
Bi9325/02: No timetable has been entered into IS.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of General biology || Bi6087 Bachelor sate exam of Cellular and molecular diagnostics || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the priciples of human pharmacogenetics, gene therapy and forenzic genetics.
Syllabus
  • Structure and expresion of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2010
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
přednášející z LF MU (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Timetable
Tue 13:00–14:50 B11/235
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of General biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the priciples of human pharmacogenetics, gene therapy and forenzic genetics.
Syllabus
  • Structure and expresion of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2009
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
přednášející z LF MU (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Timetable
Tue 15:00–16:50 BR2
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bakalářská státní závěrečná zkouška z Molekulární biologie a genetiky || Bi6082 Bakalářská státní závěrečná zkouška z Obecné biologie || Bi6087 Bakalářská státní závěrečná zkouška z Buněčné a molekulární diagnostiky || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the priciples of human pharmacogenetics, gene therapy and forenzic genetics.
Syllabus
  • Structure and expresion of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2008
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
prof. RNDr. Renata Veselská, Ph.D., M.Sc. (lecturer)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
přednášející z LF MU (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Renata Veselská, Ph.D., M.Sc.
Timetable
Mon 14:00–15:50 C03/117
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bakalářská státní závěrečná zkouška z Molekulární biologie a genetiky || Bi6082 Bakalářská státní závěrečná zkouška z Obecné biologie || Bi6087 Bakalářská státní závěrečná zkouška z Buněčné a molekulární diagnostiky || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into various areas of human genetics. At the end of this course, students should be familiar with the structure of the human genome and principles of methods used in its analysis, with the use of information gained under the Human Genome Project framework, and with molecular aspects of human evolution. They should also understand molecular principles of genetic diseases in human, as well as basics of pharmacogenetics and gene therapy.
Syllabus
  • Structure and expresion of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Complex diseases. Pharmacogenetics. Gene therapy.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Assessment methods
Presentations by professionals in the sectors. Written test.
Language of instruction
Czech
Further Comments
Study Materials
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2007
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
prof. RNDr. Renata Veselská, Ph.D., M.Sc. (lecturer)
LF MU (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Renata Veselská, Ph.D., M.Sc.
Timetable
Mon 14:00–15:50 107
Prerequisites (in Czech)
B7250 Human genetics || Bi7250 Human genetics
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Cílem přednášky je seznámit studenty se strukturou a expresí lidského genomu, s principy metod, které se používají při jeho analýze, s molekulárním základem genetických chorob a využitím poznatků získaných v Projektu lidský genom (HGP)
Syllabus
  • Projekt lidský genom, historie, principy mapování lidského genomu. Konstrukce fyzikálních, genetických a transkripčních map. Sekvencování lidského genomu a analýza sekvenčních dat. Organizace a exprese lidského genomu. Multigenové rodiny a repetitivní DNA. Mutace a nestability v lidském genomu. Identifikace genů podmiňujících lidské choroby. Molekulární patologie. Genetické testování jedinců a populací. Somatické mutace a rakovina. Komplexní choroby. Genová terapie.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Language of instruction
Czech
Further Comments
Study Materials
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2006
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
prof. RNDr. Renata Veselská, Ph.D., M.Sc. (lecturer)
LF MU (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Renata Veselská, Ph.D., M.Sc.
Timetable
Fri 9:00–10:50 BR1
Prerequisites (in Czech)
B7250 Human genetics || Bi7250 Human genetics
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Cílem přednášky je seznámit studenty se strukturou a expresí lidského genomu, s principy metod, které se používají při jeho analýze, s molekulárním základem genetických chorob a využitím poznatků získaných v Projektu lidský genom (HGP)
Syllabus
  • Projekt lidský genom, historie, principy mapování lidského genomu. Konstrukce fyzikálních, genetických a transkripčních map. Sekvencování lidského genomu a analýza sekvenčních dat. Organizace a exprese lidského genomu. Multigenové rodiny a repetitivní DNA. Mutace a nestability v lidském genomu. Identifikace genů podmiňujících lidské choroby. Molekulární patologie. Genetické testování jedinců a populací. Somatické mutace a rakovina. Komplexní choroby. Genová terapie.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Language of instruction
Czech
Further Comments
Study Materials
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2005
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer)
LF MU, BFÚ AV (lecturer)
prof. RNDr. Jiří Doškař, CSc. (lecturer)
prof. RNDr. Renata Veselská, Ph.D., M.Sc. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Jiří Doškař, CSc.
Timetable
Fri 10:00–11:50 B1,01004
Prerequisites (in Czech)
B7250 Human genetics || Bi7250 Human genetics
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Cílem přednášky je seznámit studenty se strukturou a expresí lidského genomu, s principy metod, které se používají při jeho analýze, s molekulárním základem genetických chorob a využitím poznatků získaných v Projektu lidský genom (HGP)
Syllabus
  • Projekt lidský genom, historie, principy mapování lidského genomu. Konstrukce fyzikálních, genetických a transkripčních map. Sekvencování lidského genomu a analýza sekvenčních dat. Organizace a exprese lidského genomu. Multigenové rodiny a repetitivní DNA. Mutace a nestability v lidském genomu. Identifikace genů podmiňujících lidské choroby. Molekulární patologie. Genetické testování jedinců a populací. Somatické mutace a rakovina. Komplexní choroby. Genová terapie.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Language of instruction
Czech
Further Comments
Study Materials
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2004
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
PřF a LF MU, BFÚ AV (lecturer)
prof. RNDr. Jiří Doškař, CSc. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Jiří Doškař, CSc.
Timetable
Fri 9:00–10:50 B1,01004
Prerequisites (in Czech)
B7250 Human genetics || Bi7250 Human genetics
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Cílem přednášky je seznámit studenty se strukturou a expresí lidského genomu, s principy metod, které se používají při jeho analýze, s molekulárním základem genetických chorob a využitím poznatků získaných v Projektu lidský genom (HGP)
Syllabus
  • Projekt lidský genom, historie, principy mapování lidského genomu. Konstrukce fyzikálních, genetických a transkripčních map. Sekvencování lidského genomu a analýza sekvenčních dat. Organizace a exprese lidského genomu. Multigenové rodiny a repetitivní DNA. Mutace a nestability v lidském genomu. Identifikace genů podmiňujících lidské choroby. Molekulární patologie. Genetické testování jedinců a populací. Somatické mutace a rakovina. Komplexní choroby. Genová terapie.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Language of instruction
Czech
Further Comments
Study Materials
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2003
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
PřF a LF MU, BFÚ AV (lecturer)
prof. RNDr. Jiří Doškař, CSc. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Jiří Doškař, CSc.
Prerequisites (in Czech)
B7250 Human genetics || Bi7250 Human genetics
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Cílem přednášky je seznámit studenty se strukturou a expresí lidského genomu, s principy metod, které se používají při jeho analýze, s molekulárním základem genetických chorob a využitím poznatků získaných v Projektu lidský genom (HGP)
Syllabus
  • Projekt lidský genom, historie, principy mapování lidského genomu. Konstrukce fyzikálních, genetických a transkripčních map. Sekvencování lidského genomu a analýza sekvenčních dat. Organizace a exprese lidského genomu. Multigenové rodiny a repetitivní DNA. Mutace a nestability v lidském genomu. Identifikace genů podmiňujících lidské choroby. Molekulární patologie. Genetické testování jedinců a populací. Somatické mutace a rakovina. Komplexní choroby. Genová terapie.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2002

The course is not taught in Autumn 2002

Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
LF a PřF MU, BFÚ AV (lecturer)
prof. RNDr. Jiří Doškař, CSc. (lecturer)
prof. RNDr. Jiřina Relichová, CSc. (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites (in Czech)
Bi7250 Human genetics
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Cílem přednášky je seznámit studenty se strukturou a expresí lidského genomu, s principy metod, které se používají při jeho analýze, s molekulárním základem genetických chorob a využitím poznatků získaných v Projektu lidský genom (HGP)
Syllabus
  • Projekt lidský genom, historie, principy mapování lidského genomu. Konstrukce fyzikálních, genetických a transkripčních map. Sekvencování lidského genomu a analýza sekvenčních dat. Organizace a exprese lidského genomu. Multigenové rodiny a repetitivní DNA. Mutace a nestability v lidském genomu. Identifikace genů podmiňujících lidské choroby. Molekulární patologie. Genetické testování jedinců a populací. Somatické mutace a rakovina. Komplexní choroby. Genová terapie.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Language of instruction
Czech
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2011 - acreditation

The information about the term Autumn 2011 - acreditation is not made public

Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
RNDr. Vladimíra Vallová, Ph.D. (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bachelor state exam of Molecular biology and genetics || Bi6082 Bachelor state exam of General biology || Bi6087 Bachelor state exam of Cellular and molecular diagnostics || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the priciples of human pharmacogenetics, gene therapy and forenzic genetics.
Syllabus
  • Structure and expresion of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2010 - only for the accreditation
Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
RNDr. Vladimíra Vallová, Ph.D. (lecturer)
přednášející z LF MU (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: RNDr. Vladimíra Vallová, Ph.D.
Prerequisites (in Czech)
( B7250 Human genetics || Bi7250 Human genetics ) && ( Bi6081 Bakalářská státní závěrečná zkouška z Molekulární biologie a genetiky || Bi6082 Bakalářská státní závěrečná zkouška z Obecné biologie || Bi6087 Bakalářská státní závěrečná zkouška z Buněčné a molekulární diagnostiky || SOUHLAS )
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of this course is to provide students a molecular-genetic insight into selected areas of human genetics. At the end of this course, students should be able to describe the structure of the human genome and apply the principles of methods used in its analysis. They should also understand the Human Genome Project (HGP) and interpret the use of information gained under HGP framework. They should also compose molecular aspects of human evolution and understand molecular principles of genetic diseases in human (monogenic and polygenic), as well as formulate the priciples of human pharmacogenetics, gene therapy and forenzic genetics.
Syllabus
  • Structure and expresion of human genome. Multigene families and repetitive DNA. Polymorphism in human DNA; detection and screening of mutation in human genome. Gene identification and isolation methods. Molecular aspects of human evolution. Human Genome Project, history and principles of human genome mapping. Somatic mutations and cancer. Molecular pathology. Complex diseases. Pharmacogenetics. Gene therapy. Forensic genetics.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Teaching methods
Presentations by experts in the sectors. The Powerpoint presentations are used.
Assessment methods
Written test. Student selects one or more possibility from 4 answers. To pass the exam, 60% of the points is required.
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.

Bi9325 Human molecular genetics

Faculty of Science
Autumn 2007 - for the purpose of the accreditation
Extent and Intensity
2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
Ferák (lecturer), prof. RNDr. Jiří Doškař, CSc. (deputy)
prof. RNDr. Renata Veselská, Ph.D., M.Sc. (lecturer)
LF MU (lecturer)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Renata Veselská, Ph.D., M.Sc.
Prerequisites (in Czech)
B7250 Human genetics || Bi7250 Human genetics
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Cílem přednášky je seznámit studenty se strukturou a expresí lidského genomu, s principy metod, které se používají při jeho analýze, s molekulárním základem genetických chorob a využitím poznatků získaných v Projektu lidský genom (HGP)
Syllabus
  • Projekt lidský genom, historie, principy mapování lidského genomu. Konstrukce fyzikálních, genetických a transkripčních map. Sekvencování lidského genomu a analýza sekvenčních dat. Organizace a exprese lidského genomu. Multigenové rodiny a repetitivní DNA. Mutace a nestability v lidském genomu. Identifikace genů podmiňujících lidské choroby. Molekulární patologie. Genetické testování jedinců a populací. Somatické mutace a rakovina. Komplexní choroby. Genová terapie.
Literature
  • Human molecular genetics. Edited by Tom Strachan - Andrew P. Read. 1st ed. Oxford: BIOS Scientific Publishers, 1997, xiv, 597 s. ISBN 1-872748-69-4. info
Language of instruction
Czech
Teacher's information
http://orion.sci.muni.cz/kgmb/student/9325.htm
The course is also listed under the following terms Autumn 2010 - only for the accreditation, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, autumn 2017, Autumn 2018, Autumn 2019, Autumn 2020, autumn 2021, Autumn 2022, Autumn 2023, Autumn 2024.