C7999 Advanced Methods of NMR Spectroscopy

Faculty of Science
Autumn 2003
Extent and Intensity
0/0/2. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: k (colloquium). Other types of completion: zk (examination), z (credit).
Teacher(s)
RNDr. Dalibor Dastych, Dr. (seminar tutor)
prof. RNDr. Radek Marek, Ph.D. (seminar tutor)
prof. RNDr. Jiří Pinkas, Ph.D. (seminar tutor)
Guaranteed by
prof. RNDr. Radek Marek, Ph.D.
Chemistry Section – Faculty of Science
Contact Person: prof. RNDr. Radek Marek, Ph.D.
Prerequisites (in Czech)
Kurz je určen studentům kateder anorganické a organické chemie. Podmínkou účasti je absolvování jedné z následujících přednášek: NMR - Strukturní analýza C8950, Multinukleární NMR spektroskopie C 6800 nebo Fyzikálně chemické základy NMR C5320
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 14 fields of study the course is directly associated with, display
Course objectives
Advanced methods of 1D and 2D NMR spectroscopy of small molecules.
Syllabus
  • 1. Basic 1D NMR spectra, pulse sequence, acquisition parameters, pulse calibration (direct and indirect), probehead exchange 2. Processing and parameters, temperature measurement 3. Homonuclear 2D chemical shift correlation experiments: 1H-1H COSY, 31P-31P COSY, MQF-COSY, NOESY 4. Heteronuclear 2D chemical shift correlation experiments: 31P-19F HETCOR, COLOC 5. Inverse (proton) detection HSQC, HMQC, HMBC, pulsed-field gradients 6. Measurement of 15N nucleus (direct and indirect detection), nucleus with spin > 1/2 (14N, 17O), 29Si, 77Se, 111 a 113Cd, 117 a 119Sn, 195Pt 7. Selective and shaped pulses, selective NOE, combined (hybrid) experiments - HSQC-TOCSY
Literature
  • Claridge, Timothy D.W. High-Resolution NMR Techniques in Organic Chemistry, Amsterdam, Pergamon, 1999, ISBN 0-08-042798-7
  • Braun, S. - Kalinowski, H.O. - Berger, S. 100 and More Basic NMR Experiments, Weinheim, VCH, 1996, ISBN 3-527-29091-5
Assessment methods (in Czech)
Výuka probíhá u spektrometru v NMR laboratoři. Zápočet bude udělen po zpracování samostatného projektu (měření a interpretace neznámého vzorku).
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Autumn 2007 - for the purpose of the accreditation, Autumn 2010 - only for the accreditation, Autumn 2002, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2011 - acreditation, Autumn 2012.
  • Enrolment Statistics (Autumn 2003, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2003/C7999