CG030 Structure and function of protein complexes

Faculty of Science
spring 2018
Extent and Intensity
2/0/0. 2 credit(s) (plus 2 credits for an exam). Type of Completion: zk (examination).
Teacher(s)
doc. Mgr. Jan Paleček, Dr. rer. nat. (lecturer)
doc. RNDr. Jaromír Marek, Ph.D. (lecturer)
Guaranteed by
doc. Mgr. Jan Paleček, Dr. rer. nat.
National Centre for Biomolecular Research – Faculty of Science
Supplier department: National Centre for Biomolecular Research – Faculty of Science
Timetable
Thu 11:00–12:50 C02/211
Prerequisites
Knowledge in molecular biology, biochemistry.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
introduce various protein complexes (from simple complexes to molecular machines). explain relationships between composition, structure and function of selected protein complexes.
Learning outcomes
Students will acquire information about proteins and protein complexes. They will understand architecture and function of the best known molecular complexes.
Syllabus
  • Structure and analytical approaches to protein complexes. Posttranslational modifications of proteins. Protein-protein interactions. Assembly and functions of the best known protein complexes. Chromatin protein complexes. Evolution of proteins and protein complexes.
Literature
    recommended literature
  • 3. Uetz P. and Finley RL Jr.: From protein networks to biological systems, FEBS Lett. 2005, 21;579(8):1821-7
  • 1. Textbook of Structural Biology, A. Liljas, L. Liljas, J. Piskur, G. Lindblom, P. Nissen, M. Kjeldgaard: World Scientific Publishing Co., Singapore, 2009
  • 2. Protein-protein interactions. Edited by E.A. Golemis and P.D. Adams. 2nd ed. Cold Spring Harbor, New York, N.Y.: Cold Spring Harbor Laboratory Press, 2005
Teaching methods
Reading, lectures from specialists
Assessment methods
presentation and discussion of selected topics, test
Language of instruction
Czech
Follow-Up Courses
Further Comments
Study Materials
The course is taught annually.
Teacher's information
http://genpro.sci.muni.cz/
The course is also listed under the following terms Autumn 2010 - only for the accreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2019, Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024, Spring 2025.
  • Enrolment Statistics (spring 2018, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2018/CG030