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Course Information

BVZF0521p Basics of Pharmacology I - lecture

Faculty of Medicine
Autumn 2008

Extent and Intensity

1/0/0. 1 credit(s). Type of Completion: z (credit).

Teacher(s)

prof. MUDr. Alexandra Šulcová, CSc. (lecturer)
prof. MUDr. Eva McCaskey Hadašová, CSc. (lecturer)
MUDr. Jana Nováková, Ph.D. (lecturer)
MUDr. Jana Pistovčáková, Ph.D. (lecturer)
Mgr. MVDr. Leoš Landa, Ph.D. (lecturer)
PharmDr. Jan Juřica, Ph.D. (lecturer)
PharmDr. Ondřej Zendulka, Ph.D. (lecturer)
MUDr. Mgr. Karel Šlais, Ph.D. (lecturer)
MVDr. Dagmar Vršková, Ph.D. (lecturer)

Supervisor

prof. MUDr. Alexandra Šulcová, CSc.
Department of Pharmacology - Theoretical Departments - Faculty of Medicine
Contact Person: Renata Bláblová

Timetable

each even Thursday 13:00–14:40 P31

Prerequisites (in Czech)

( BVBC0322p Nutritional Biochemistry II-l || BVBC0444p Biochemistry IV -lec. ) && BVTO041c Toxicology -p. && BVTO041p Toxicology -lec.

Course Enrollment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

Fields of study the course is directly associated with

• Human Nutrition (programme LF, B-SZ)

Course objectives

From the course on pharmacology students are expected to obtain: a) from lectures and seminars: a clarification of integration in the field of biomedical subjects such as chemistry, physiology, molecular biology, pathology and pathological physiology enabling them to understand why, what mechanism by, and what conditions on, drugs and their combinations may elicit therapeutic, adverse, and toxic effects. They will acquire an orientation in drug classes according to their main therapeutic indications with an attention paid to common drug-drug interactions. Information on drug development process, rules of preclinical and clinical drug testing will also be given. b) from practicals: a training in practical skills in "pharmacological thinking" in cases of need to make a choice of drug, dosing regimen, route and techniques of administration, and an elimination of adverse interactions with drugs simultaneously given.

Syllabus

• 1.LECTURE: Introduction to pharmacology. Basic pharmacological terms, definitions. Drug dosage forms and application routes. Legislative of drug prescription and drugs of abuse.
• 2.LECTURE: Drug interactions. Preclinical and clinical examination and evaluation.
• 3.LECTURE: Drug classification. Mechanisms of drug effects. Basics of pharmacokinetics.
• 4.LECTURE: Adverse drug effects. General management of poisoning. Drug dependence. Rational Pharmacotherapy.
• 5.LECTURE: Autonomic nervous systems, mediators, overview. Adrenergic mediation, alfa and beta sympatomimetics.
• 6.LECTURE: Allergy and therapy. Histamine and antihistaminic agents.
• 7.LECTURE: Pharmacotherapy of cancer. Immunomodulation. Immunosuppressants.

Literature

• Farmakologie pro studenty zdravotnických oborů. Edited by Jiřina Martínková. 1. vyd. Praha: Grada, 2007. 379 s. ISBN 978-80-247-1356. info
• MACH, Ivan. Doplňky stravy na našem trhu. Vyd. 1. Praha: Svoboda Servis, 2006. 118 s. ISBN 80-86320-46-4. info
• PERLÍK, František. Základy farmakologie :klinická a speciální farmakologie /. 1. vyd. Praha: Karolinum, 2005. 190 s. ISBN 80-246-1139-2. info
• LÜLLMANN, Heinz. Barevný atlas farmakologie. Translated by Elfrída Mühlbachová. 2. přeprac. a dopl. vyd. Praha: Grada Publishing, 2001. 382 s. ISBN 80-7169-973-X. info
• HYNIE, Sixtus. Farmakologie v kostce. 2. přepr. vyd. Praha: Triton, 2001. 520 s. ISBN 80-7254-181-1. info
• HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996. 272 s. ISBN 80-7184-184-6. info
• HYNIE, Sixtus. Farmakologie pro bakalářské studium. 2. přeprac. vyd. Praha: Karolinum, 1996. s. i-x, 27. ISBN 80-7184-185-4. info
• Vybrané kapitoly z učebnice: http://books.google.cz/books?id=7lNQpLuETq4C&printsec=frontcover&dq=farmakologie&lr=&as_brr=3#PPA4,M1
• Vybrané kapitoly z učebnice: http://books.google.cz/books?ct=result&q=farmakologie&lr=&as_brr=3&sa=N&start=0

Assessment methods

During the studying the student has to prove active knowledge of pharmacology acquired to get the credit. The student has to pass the final written multiple-choice test.

Further comments (probably available only in Czech)

The course is taught annually.

Teacher's information

Přednášky ve čtvrtek {18.9.2008}, 2.10.2008, 16.10.2008, 30.10.2008, 13.11.2008, 27.11.2008, 11.12.2008 - 13.00 - 14.40 hod: Joštova 10, Brno - místnost P31.

Cvičení ve čtvrtek 25.9.2008, 9.10.2008, 23.10.2008, 6.11.2008, 20.11.2008, 4.12.2008, 18.12.2008 - 13.00 - 14.40 hod: Farmakologický ústav, Tomešova 12, Brno.

Úřední hodiny sekretariátu Farmakologického ústavu, Tomešova 12, denně 13.00 - 14.00 h, tel.: 54949 3070.

The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007.

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