Bi8113 Microfluidics

Faculty of Science
Autumn 2015

The course is not taught in Autumn 2015

Extent and Intensity
2/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
prof. RNDr. Zbyněk Prokop, Ph.D. (lecturer)
Guaranteed by
prof. Mgr. Jiří Damborský, Dr.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Zbyněk Prokop, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Prerequisites
Bi1510 Mgr. state exam
Basic knowledge of chemistry, biochemistry and molecular biology.
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The objective of the course is to provide students with modern trends in the field of microfluidics, the basic methods of chip design and fabrication and its application in life sciences and biotechnology. Miniaturization and automation are key trends of modern experimental methods in life sciences and biomedicine. Microfluidics, one of the dominant technology in these trends, allows the handling of very small liquid volumes (nano-, pico- sometimes femto-liters) in micro channels with dimensions of tens of micrometers, comparable to the width of a human hair. These miniaturized laboratory systems - lab on a chip - allows for large number of individual experiments in a short time, with minimal sample requirement. Laboratory on a chip is the base of the latest technologies such as "Next Generation" sequencing or "Single Molecule" diagnosis. Like in the electronics industry, miniaturization and integration of electric circuits into a silicon chip boosted the revolution in computer technology, microfluidics and miniaturization of laboratory experiments to on chip micro-dimensions promote cutting-edge advances in life sciencies and biomedicine.
Syllabus
  • 1. Opening lecture / Organization of the course
  • 2. Introduction to microfluidics
  • 3. Key physical principles of microdomain
  • 4. Designing microfludic chip
  • 5. Chip fabrication technologies
  • 6. On Chip detection methods
  • 7. Continuous-flow microfluidics
  • 8. Droplet microfluidics
  • 9. Digital microfluidics
  • 10. Paper microfluidics
Literature
  • Introduction to microfluidics. Edited by P. Tabeling. New York: Oxford University Press, 2005, vii, 301p. ISBN 0198568649. info
Teaching methods
During lecturing, the PowerPoint presentations are used, PDF hand-out materials and selected articles are available before each course, short written tests at the beginning of selected lectures and short exercises and discussions during lectures are prepared.
Assessment methods
Short written tests will be prepared at the beginning of lectures No. 4, 6, 8 and 10. Each short written test will contain ten questions on the previous curriculum. Final evaluation of the course will be based on the cumulative results of these short written tests. In the case that (i) the student will not fulfill all short tests, (ii) will not be successful in the short tests, or (iii) is not satisfied with the result of the short testing, he or she will be evaluated by the general written test. Terms for the general written test will be listed in the current examination period, the test will contain 50 questions from overall course content, the time to complete the test will be 1 hour. The student receives a score according to the following criteria (success in test questions / evaluation: 100-91% / A; 90-76% / B, 75-61% / C, 60-46% / D, 45-31% / E; 30- 0% / F).
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
General note: Předmět není v akademickém roce 2015/2016 vypisován.
  • Permalink: https://is.muni.cz/course/sci/autumn2015/Bi8113