Bi8250 Developmental and Comparative Immunology

Faculty of Science
Spring 2011
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Teacher(s)
RNDr. Pavel Hyršl, Ph.D. (lecturer)
Supervisor
RNDr. Pavel Hyršl, Ph.D.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: RNDr. Pavel Hyršl, Ph.D.
Timetable
Thu 11:00–12:50 BR1
Prerequisites (in Czech)
Bi5220 Immunology
Course Enrollment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
Fields of study the course is directly associated with
  • General Biology (programme PřF, M-BI, specialization Physiology of Animals)
  • General Biology (programme PřF, N-BI, specialization Physiology of Animals)
Course objectives
At the end of this course, students should be able to: understand and be able to explain differences in immune system between main animal groups; compare immune system of invertebrates and vertebrates; interpret scientific articles about invertebrate and vertebrate immunology; determine differences in human immune system in contrast to other mammals;
Syllabus
  • 1. Introduction, defence mechanisms of organisms
  • 2. Invertebrate immunology - evolutionary diagram of immune reactions
  • 3. Porifera and Cnidaria (Diblastistica), Nemathelmintes, Nemertea
  • 4. Sipunculida, Annelida, Mollusca
  • 5. Antennata (mainly Insecta)
  • 6. Urochordata, Echinodermata, Cephalochordata
  • 7. Vertebrate immunology evolutionary diagram of immune reactions
  • 8. Fish (Pisces) immunity
  • 9. Amphibian (Amphibia) immunity
  • 10. Reptiles (Reptilia) immunity
  • 11. Birds (Aves) immunity
  • 12. Comparison with mammals immune system
Literature
  • BECKAGE, Nancy E. Insect immunology. 1st ed. Amsterdam: Elsevier, 2008. 348 s., [6. ISBN 978-0-12-373976. info
  • CRUSE, Julius M. and Robert Edwin LEWIS. Illustrated dictionary of immunology. Boca Raton: CRC Press, 1994. 327 s.,6 s. ISBN 0-8493-4557-X. info
  • Turner R. J.: Immunology: A Comparative Approach, John Wiley & Sons Inc. 1994.
  • Comparative immunology. info
Teaching methods
lectures, 2x per semestre class discussion - students should study in advance english literature, study materials available on IS
Assessment methods
final written test, oral exam
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Teacher's information
Přednáška navazuje na předmět imunologie, který se věnuje především obecným principům imunitní odpovědi se zaměřením na imunitní systém člověka. V~rámci přednášek bude probírána evoluce, anatomie a funkce imunitního systému bezobratlých a obratlovců. Všechny tyto parametry budou porovnávány s~imunitním systémem savců, důraz bude kladen hlavně na odlišnosti a specifika těchto systémů. Jednotlivé skupiny živočichů vyvinuly řadu účinných obranných reakcí, které jsou založeny hlavně na rozpoznání cizorodých struktur unvitř těla (přirozená imunita) a u~evolučně vyspělejších skupin také na imunologické paměti (adaptivní imunita). Úvodní přednáška bude věnována obecnému přehledu obranných mechanismů, navázáno bude kmenem Porifera (houbovci), kdy lze poprvé použít termín imunita (graft rejection) a dále bude pokračováno podle platného systému živočichů až k~třídě Mammalia (savci). Lectures will link to the course of immunology, which is based on general principles if immune responses with emphasis on human immune system mainly. Lectures from developmental and comparative immunology will be foccused on evolution, anatomy and function of invertebtate and vertebrate immune system (except mammals). All parameters will be compared with mammals immune system, the emphasis will be on differencies and specifics between these systems. Each group of animals developed several effective immune responses, which are based on non-self recognition mainly (innate immunity) and by evolutionary more developed animals by immunilogical memmory (adaptive immunity). Lectures will start by general overview of immune reactions and will follow with Porifera (Sponges), where we can firstly use the term immunity (graft rejection). In the rest of lectures will be discussed evolutionary higher organisms till Mammalia (Mammals).
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, spring 2012, spring 2012 - acreditation, spring 2013, spring 2014.
  • Enrollment Statistics (Spring 2011, recent)
  • Permalink: https://is.muni.cz/course/sci/spring2011/Bi8250

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