Information System of Masaryk University 

Course Information

C6220 Clinical Biochemistry

Faculty of Science
autumn 2012

Extent and Intensity

4/0/0. 4 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Alternate Types of Completion: k (colloquium).

Teacher(s)

doc. RNDr. Michaela Wimmerová, Ph.D. (lecturer)

Supervisor

doc. RNDr. Michaela Wimmerová, Ph.D.
Department of Biochemistry - Chemistry Section - Faculty of Science
Contact Person: doc. RNDr. Michaela Wimmerová, Ph.D.
Dodavatelské pracoviště: Department of Biochemistry - Chemistry Section - Faculty of Science

Timetable

Thu 10:00–13:50 A11/205

Prerequisites (in Czech)

C4182 Biochemistry II || C3580 Biochemistry || C5720 Biochemistry
předpokládá se absolvování základní přednášky z biochemie a znalost základních metabolických drah na úrovni buňky.

Course Enrollment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.

Fields of study the course is directly associated with

• Cellular and Molecular Diagnostics (programme PřF, B-BI)
• Biochemistry (programme PřF, N-CH)

Course objectives

The goal of this course is to provide general basic knowledge about biochemical and molecular aspects of pathobiological processes and use of biochemical tests to obtain diagnostic information. The course consisted from two part, pathobiochemistry and methods in clinical biochemistry.

At the end of the course students should be able to:
understand to basic physiological events in healthy human organism;
understand and explain relationships between analytical parameters determined in clical biochemistry laboratories ans their diagnostic indication;
interpret basic non-physiological results and give them into a context of the potential disease

Syllabus

• SECTION ONE: Laboratory techniques
• Basic laboratory principles and calculations
• Collection and handling of patient specimens
• Methods in clinical biochemistry
• Analysis of metabolites, proteins and enzymes
• Automation
• Laboratory statistics, reference values, quality control
• Evaluation of methods
• Section TWO: Pathobiochemistry
• Body water and electrolytes
• Renal function
• Acid-base control and acid-base disorders
• Liver function
• Diabetes mellitus
• Disorders of lipid and lipoprotein metabolism
• Gastrointestinal function, pancreatic function, digestive disease
• Bone disease
• Biochemistry of muscle
• Inborn errors of metabolism
• Endocrine function
• Tumor markers

Literature

• Laboratorní diagnostika. Edited by Tomáš Zima. 1. vyd. Praha: Galén, 2003. xxxii, 728. ISBN 80-7262-201-3. info
• RACEK, Jaroslav. Klinická biochemie (Clinical chemistry). 1. vyd. Praha: Galén, 1999. 316 pp. ISBN 80-7262-023-1. info
• Clinical biochemistry :metabolic and clinical aspects. Edited by S. K. Bangert - William J. Marshall. New York: Churchill Livingstone, 1995. xi, 854 s. ISBN 0-443-04341-8. info
• MASOPUST, Jaroslav. Klinická biochemie. Požadování a hodnocení biochemických vyšetření. (Clinical chemistry.). 1. vyd. Praha: Karolinum, 1998. 832 pp. část I. a část II. ISBN 80-7184-649-3. info
• Clinical guide to laboratory tests. Edited by Norbert W. Tietz. 3rd ed. Philadelphia: W.B. Saunders Company, 1995. xxxix, 109. ISBN 0-7216-5035-. info
• KARLSON, Peter, Wolfgang GEROK and W. GROSS. Pathobiochemie. 1. vyd. Praha: Academia, 1987. 480 s. info
• RACEK, Jaroslav. Klinická biochemie. 2., přeprac. vyd. Praha: Galén, 2006. 329 s. ISBN 80-7262-324-9. info

Teaching methods

lectures several courses a held by professionals coming from external hospital clinical biochemistry laboratories

Assessment methods

written and oral exam

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Listed among pre-requisites of other courses

• C6230 Clinical Biochemistry - laboratory course
  NOW(C6220) && SOUHLAS  

Teacher's information

http://orion.chemi.muni.cz/michaw/teaching.htm
Souběžně s přednáškou je možno absolvovat cvičení z klinické biochemie (C6230). Doprovodný materiál je možno získat na webové stránce: URL>http://orion.chemi.muni.cz/michaw/vyuka/blany.htm

The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2000, Spring 2001, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, autumn 2011, Autumn 2011 - acreditation, autumn 2013.

---

• Enrollment Statistics (recent)
  
• Permalink: https://is.muni.cz/course/sci/autumn2012/C6220

---