Information System of Masaryk University 

Course Information

C6230 Clinical Biochemistry - laboratory course

Faculty of Science
autumn 2011

Extent and Intensity

0/4/0. 4 credit(s). Type of Completion: z (credit).

Teacher(s)

doc. RNDr. Michaela Wimmerová, Ph.D. (lecturer)
Mgr. Lenka Adamová (seminar tutor)
Mgr. Jan Komárek (seminar tutor)
Mgr. Jana Mrázková (seminar tutor)
Mgr. Petra Sýkorová (seminar tutor)

Supervisor

doc. RNDr. Michaela Wimmerová, Ph.D.
Department of Biochemistry - Chemistry Section - Faculty of Science
Contact Person: doc. RNDr. Michaela Wimmerová, Ph.D.

Timetable of Seminar Groups

C6230/01 Tue 9:00–12:50 A15-212
C6230/02 Tue 13:00–16:50 A15-212

Prerequisites (in Czech)

NOW ( C6220 Clinical Biochemistry ) && SOUHLAS
Předpokladem zápisu je současné absolvování předmětu klinická biochemie (C6230). K zápisu je potřeba požádat o výjimku-souhlas učitele. Souhlas bude udělován v pořadí: Aplikovaná biochemie (předmět je povinný), Biochemie (předmět je povinně volitelný), ostatní.

Course Enrollment Limitations

The course is also offered to the students of the fields other than those the course is directly associated with.
The capacity limit for the course is 50 student(s).
Current registration and enrollment status: enrolled: 10/50, only registered: 0/50, only registered with preference (fields directly associated with the programme): 0/50

Fields of study the course is directly associated with

there are 9 fields of study the course is directly associated with, display

Course objectives

The laboratory course is designed to introduce the student to the principles and practices of clinical chemistry. Through laboratory experiences the student will develop the necessary skills to perform analytical procedures and evaluate laboratory data. The exercises familiarize the student with the performance of simple laboratory tests common in health care centers.Advanced part is focused to some special methods in laboratory diagnostics.

At the end of the course students should be able to:
understand basic principles of basic analytical parameters determination in blood serum and urine;
determine basic biochemical parameters in serum and urine;
interpret measured results in context of potential health/disease

Syllabus

• Basic course
• Chemical examination of urine
• Glucose, hemoglobin
• Alkaline phosphatase, lipids, cholesterol
• Nonprotein nitrogenous compounds in serum
• Liver biochemistry; enzymes, bilirubin
• Different approaches in isoenzyme diagnostics: creatine kinase and lactate dehydrogenase models
• Advanced course
• HPLC - assay of ascorbic acid
• LC-MS analysis and identification of a BSA proteolytic digest
• Enzyme biosensors in clinical diagnostics
• Uric acid assay using capillary zone electrophoresis
• Immunochemistry-ELISA
• Excursion to hospital and private laboratory of clinical biochemistry

Literature

• RACEK, Jaroslav. Klinická biochemie. 2., přeprac. vyd. Praha: Galén, 2006. 329 s. ISBN 80-7262-324-9. info
• Klinická biochemie :požadování a hodnocení biochemických vyšetření. Edited by Jaroslav Masopust. 1. vyd. Praha: Karolinum, 1998. 429 s. ISBN 80-7184-648-1. info

Teaching methods

home preparation, laboratory courses

Assessment methods

class discussion, written protocols, credit

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

http://orion.chemi.muni.cz/michaw/teaching.htm
Předpokladem zápisu je současné absolvování předmětu klinická biochemie (C6230). K zápisu je potřeba požádat o výjimku/souhlas učitele. Souhlas bude udělován v pořadí: Aplikovaná biochemie (předmět je povinný), Biochemie (předmět je povinně volitelný), ostatní.

The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2011 - only for the accreditation, Spring 2001, Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2011, Autumn 2011 - acreditation, autumn 2012, autumn 2013.

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• Enrollment Statistics (autumn 2011, recent)
  
• Permalink: https://is.muni.cz/course/sci/autumn2011/C6230

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